Seneca Hotel Guide - Hotels with Spa in Seneca, South Carolina

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Check availability on Seneca Hotels with Spa

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Seneca Hotels with Spa

No exact matches found, but these alternatives could be just right

Recommended hotels in Seneca

Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 star property
Seneca
9.0 out of 10, Wonderful, (1001)
"Overall great stay."
United States
Daniel
The price is €116
includes taxes & fees
19 Dec - 20 Dec
Lakeside Lodge Clemson
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 star property
Seneca
8.4 out of 10, Very good, (638)
"The stay was amazing "
United States
Tabatha
The price is €88
includes taxes & fees
20 Dec - 21 Dec
Best Western Seneca-Clemson
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very good, (664)
"Friendly check in, clean room."
United States
connie
The price is €75
includes taxes & fees
14 Dec - 15 Dec
Quality Inn Seneca Clemson Area US-123
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (49)
"The place was absolutely magnificent."
United States
David
The price is €122
includes taxes & fees
10 Dec - 11 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 star property
Seneca
9.2 out of 10, Wonderful, (788)
"Staff was very friendly. Everything was very clean. Very quite in room"
United States
Dianna
The price is €90
includes taxes & fees
26 Dec - 27 Dec
Tru by Hilton Seneca Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is €109
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites Seneca Clemson Univ Area
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
Seneca
9.2 out of 10, Wonderful, (660)
"Great place to stay"
United States
Jose
The price is €98
includes taxes & fees
25 Dec - 26 Dec
Hampton Inn & Suites Seneca-Clemson Area
Property grounds
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Seneca
10.0 out of 10, Exceptional, (12)
"Great hidden gem in Seneca for a Clemson football weekend. Property was amazing, loved the animals…..we will be back! "
United States
Allison H.
The price is €183
includes taxes & fees
7 Dec - 8 Dec
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Smart TV, fireplace
Enjoy one of our RV units son less of a headache for you this vacation!

Enjoy one of our RV units son less of a headache for you this vacation!

Seneca
7.0 out of 10, Good, (2)
"Very nice camper in a good location close to Clemson. Perfect for attending games. Took us 10-15 minites to get to stadium. All on back roads.Host was responsive to messages and requests. Only thing I would recommend to host is to reach out a couple days before just to give you check in details. Check in was very simple, but i had to reach to them to get the details. Would definitely stay here again!!"
United States
Hunter P.
Enjoy one of our RV units son less of a headache for you this vacation!
Fridge, microwave, oven, stovetop
Tucker Farm Cottage on Century Farm

Tucker Farm Cottage on Century Farm

Seneca
10.0 out of 10, Exceptional, (31)
"Excellent stay, beautiful area!"
United States
Barbara W.
Tucker Farm Cottage on Century Farm
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"X"
Stephen 3-night trip
Posted 7 days ago
Hampton Inn & Suites Seneca-Clemson Area

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Frequently asked questions

Looking for a spa hotel in Seneca?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Discover the lakeside setting in Seneca—worth a picture or two! Make sure you enjoy the coffee shops during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Seneca?
Take in the sights and attractions that Seneca offers with a visit to Seneca Historic District, Lake Keowee and Keowee Key Golf Course. If you have extra time while you're in the area, you might want to see Lake Hartwell and The Gauntlet.
What is a Seneca spa hotel?
Spa hotels in Seneca provide lodging and have an on-site spa offering services such as therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.