Serra Mesa Holidays
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Price found within the past 48 hours. Click for updated prices.
Embassy Suites by Hilton San Diego La Jolla
University City
€699
per person
19 Nov - 23 Nov
found 1 day ago
Return flight included
New York (JFK) to San Diego (SAN)
8.8/10 Excellent! (2,084 reviews)
The breakfast here is really good in comparison to other hotels (fresh made omelets are always a win) even if the rest of the fare was the average you get anywhere else. Service was good. Our room was clean and spacious, and although a big dated (older furniture, older mini-fridge, old style bathroom, the hand-rest of the sofa was peeling) it was a comfortable stay (except for the pillows that were not great).
Reviewed on 19 Oct 2026
Hotel Republic San Diego, Autograph Collection
Downtown San Diego
€653
per person
19 Nov - 23 Nov
found 1 day ago
Return flight included
New York (JFK) to San Diego (SAN)
9/10 Wonderful! (1,042 reviews)
Nice property in downtown San Diego, when I return I’ll book there, convenient to the airport, within walking distance to many restaurants, staff was exceptional, we checked out and they stored our bags for the day until we returned later that evening
Reviewed on 18 Oct 2026
Holiday Inn Express San Diego Downtown by IHG
Downtown San Diego
€640
per person
19 Nov - 23 Nov
found 1 day ago
Return flight included
New York (JFK) to San Diego (SAN)
8.4/10 Very good! (1,722 reviews)
The room was clean, staff very helpful, breakfast was great. The pool area was under construction (only miss). Hotel is at the top of a steep inclined road.
Reviewed on 19 Oct 2026
Where to stay in Serra Mesa
Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
Downtown San Diego
3 out of top 10 points of interest in this area
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Mission Bay
1 out of top 10 points of interest in this area
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
Top hotels in Serra Mesa
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
€188
22 Oct - 23 Oct
includes taxes & fees
Handlery Hotel
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
€102
15 Nov - 16 Nov
includes taxes & fees
8.4/10 Very good! (3,010 reviews)
"The parking was a little confusing on my first time there. Scanning room card at the proper area of the machine."
Reviewed on 19 Oct 2026
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
€144
28 Oct - 29 Oct
includes taxes & fees
9.2/10 Wonderful! (4,032 reviews)
"Our room was great with a nice private balcony looking out into the bay. The pool was great and the food and drinks spot on. We will be back!"
Reviewed on 19 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Serra Mesa holiday package cost?
Be ready to book, because a trip to Serra Mesa starts from just €617. When you bundle your hotels, flights and car rentals into a package, you'll land the lowest prices.
How do I get a cheap travel package to Serra Mesa?
One of the simplest ways to save dollars (and time) is to bundle your bookings with Expedia. Flights, hotels, activities and rental cars — we've got everything you need. Pick the combination that best suits you and watch your savings pile up. Of course, a travel package is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options worldwide, which lets you customize your Serra Mesa holiday.
Where should I stay in Serra Mesa?
Most visitors to Serra Mesa put both San Diego Zoo and Balboa Park on their itineraries. Why not go for a hotel that's close to these fantastic attractions?
What are the top hotels in Serra Mesa?
Get your escape off to an excellent start by locking in a room at Central Location - 3br/2ba. Stay Weekly. Clean. It's one of most sought-after properties in Serra Mesa. Another comfortable option is Newly Remodeled Beautiful Beach Bound And Centrally Located San Diego Home.
How far in advance should I book my Serra Mesa holiday?
It's difficult to pick the best time for airfares, but we normally say the earlier, the better. Most international flights on Expedia become available up to 12 months in advance. If you're booking late, fear not. Budget prices appear from time to time just weeks before departure dates.
What does an Expedia Serra Mesa travel package include?
From flights and hotels to rental cars, Expedia can help you craft a Serra Mesa package that's perfect for you. Holidaying for a few weeks? Consider a flight, hotel and rental car bundle. If your break is short, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a cinch to plan and save.
What should I know before booking a Serra Mesa travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, you can add on things like day tours or experiences. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a Serra Mesa Expedia holiday package?
With a holiday package, you're the one in charge. Whether you'd like to fly to Serra Mesa in economy or first class, simply choose from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Serra Mesa holiday package?
Plans can change in the blink of an eye, so yes. You may be able to cancel or alter your Serra Mesa holiday package at no cost if you've booked in the last 24 hours. For bookings made more than 24 hours ago, you can still make the necessary changes, but your car rental company, hotel or airline may impose a charge. Want more information? Check out our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
Stay near popular Serra Mesa attractions
Stadium Golf Center & Batting Cages
Enjoy a round of golf in San Diego at Stadium Golf Center & Batting Cages. Attend a sporting event or discover the beautiful sunsets in this walkable area.
Things to do
San Diego: Mission Bay Sunset Cruise
€38
per adult
84% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.