
Serra Mesa Holidays
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Where to stay in Serra Mesa
Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa

Downtown San Diego
4 out of top 10 points of interest in this area
4.5/5(138 area reviews)
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Top hotels in Serra Mesa

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is €197 per night from 1 Mar to 2 Mar
€197
1 Mar - 2 Mar
includes taxes & fees
8.8/10 Excellent! (2,430 reviews)
Great family place to stay.
Reviewed on 25 Feb 2026

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is €122 per night from 1 Mar to 2 Mar
€122
1 Mar - 2 Mar
includes taxes & fees
9.2/10 Wonderful! (3,424 reviews)
Staff was very friendly and warm. Room was very nice.
Reviewed on 26 Feb 2026

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is €279 per night from 11 Mar to 12 Mar
€279
11 Mar - 12 Mar
includes taxes & fees
9/10 Wonderful! (3,354 reviews)
Room was clean but the view, the view was amazing. I so appreciate the concierge accommodating my request to be moved up to the 10th floor. It was an absolute game changer.
Reviewed on 26 Feb 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

San Diego Zoo
Come and see the power and beauty of nature up close at one of the biggest and best zoos in America.

Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Mission Beach
Enjoy the old-world charm of this seaside suburb where the beautiful people live, close to central San Diego.
Things to do

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
€84
per adult
90% of travellers recommend

San Diego: Museum of Illusions Entry Ticket
€29
per adult
84% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.




