Name: Hotel Doña Maria
Price range: €87

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)

Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

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Things to do

a narrow dirt road leading to a town in Spain

White Villages & Ronda Day Trip from Seville

€79

per adult

92% of travellers recommend

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

€39

per adult

88% of travellers recommend

Landscape of Guadalquivir river area with several buildings in view.

Guadalquivir River Criuse Tour

€19

per adult

80% of travellers recommend

Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

€110

per adult

94% of travellers recommend

Seville: Guadalquivir River Cruise

€18

per adult

80% of travellers recommend

Seville Cathedral and Giralda Guided Tour (Skip-The-Line Ticket Included)

€35

per adult

72% of travellers recommend

See all activities in Seville

Top hotels in Santa Cruz

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville

€109

1 Dec - 2 Dec

includes taxes & fees

Stay at this spa hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

9.2/10 Wonderful! (1,033 reviews)

"The drinks in the minibar are 4Euro a piece, but down the street they are cheaper in the stores. That being said if your flight comes in late (like ours did) they are cold and wonderful lol. The coffee maker amd tea maker/kettle thing was awesome! Wish there was a small microwave for bread and butter/oil ..."

Reviewed on 11 Nov 2026

Hotel Amadeus Sevilla

Calle Farnesio 6 Seville Seville

€96

9 Dec - 10 Dec

includes taxes & fees

Stay at this boutique hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the breakfast and the bar in their reviews. ...

9.6/10 Exceptional! (1,307 reviews)

"Peerfectly kept with beautiful details. this hotel is a jewel in the center of the town!"

Reviewed on 10 Nov 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2 Seville Seville

Fully refundableReserve now, pay when you stay

€406

10 Dec - 11 Dec

includes taxes & fees

Stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff in their reviews. ...

9.4/10 Exceptional! (1,000 reviews)

"Na"

Reviewed on 8 Nov 2026

Hotel Fernando III

San Jose 21 Seville Seville

€119

8 Dec - 9 Dec

includes taxes & fees

Stay at this business-friendly hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their ...

9.6/10 Exceptional! (1,378 reviews)

"이 호텔은 구시가지에 위치하고 있어서 관광을 하기에 매우 편리합니다 시설도 훌륭하여 세비야를 즐기는데 큰 도움이 되었어요"

Reviewed on 11 Nov 2026

Hotel Rey Alfonso X

Calle Ximenez De Enciso, 35 Seville Seville

€119

8 Dec - 9 Dec

includes taxes & fees

Stay at this hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...

Hotel Doña Maria

Don Remondo 19 Seville Seville

€87

15 Dec - 16 Dec

includes taxes & fees

Stay at this historic hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the helpful staff in their reviews. Popular ...

See all 2,672 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check Santa Cruz hotel availability

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

A bustling urban street lined with historic buildings and trees.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

A river with boats, a historic tower, and a cityscape with trees and buildings.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

A modern architectural structure with a unique, wave-like design.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

A large, illuminated bridge with circular arches over a calm river.

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

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