Southern Indiana Hotel Guide - Business Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana Business Hotels

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Southern Indiana business-friendly hotels

Exterior
Holiday Inn Express & Suites Evansville North by IHG

Holiday Inn Express & Suites Evansville North by IHG

Holiday Inn Express & Suites Evansville North by IHG
2.5 star property
Evansville
8.6 out of 10, Excellent, (584)
"We stayed one night - it was perfect, clean and convenient- will definitely stay here again "
United States
Jaclyn
The price is €84
includes taxes & fees
23 Jan - 24 Jan 2026
Holiday Inn Express & Suites Evansville North by IHG
Exterior
Comfort Inn Madison near Clifty Falls

Comfort Inn Madison near Clifty Falls

Comfort Inn Madison near Clifty Falls
2.5 star property
Madison
8.8 out of 10, Excellent, (665)
"Great stay, clean, and comfy bed!"
United States
cheryl
The price is €90
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Inn Madison near Clifty Falls
Lobby
Comfort Inn Ferdinand

Comfort Inn Ferdinand

Comfort Inn Ferdinand
2.5 star property
Ferdinand
8.4 out of 10, Very good, (602)
"The manager is AMAZING he went out of his way to make sure our stay was awesome can not recommend this place enough!"
United States
Jessica
The price is €81
includes taxes & fees
21 Jan - 22 Jan 2026
Comfort Inn Ferdinand
Free daily on-the-go breakfast
Hampton Inn Corydon

Hampton Inn Corydon

Hampton Inn Corydon
2.5 star property
Corydon
8.8 out of 10, Excellent, (602)
"Courteous staff, clean room"
United States
Steven
The price is €100
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn Corydon
Lobby
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North
2.5 star property
Sellersburg
8.4 out of 10, Very good, (1008)
"Friendly service, clean rooms, comfortable beds, "
United States
Debra
The price is €69
includes taxes & fees
28 Dec - 29 Dec
Ramada by Wyndham Sellersburg/Louisville North
Exterior
Garner Hotel Evansville East by IHG

Garner Hotel Evansville East by IHG

Garner Hotel Evansville East by IHG
3.0 star property
Evansville
8.8 out of 10, Excellent, (81)
"Peaceful place to stay."
United States
Deborah
The price is €74
includes taxes & fees
28 Dec - 29 Dec
Garner Hotel Evansville East by IHG
Exterior
Hyatt Place Evansville

Hyatt Place Evansville

Hyatt Place Evansville
3.0 star property
Downtown Evansville
9.4 out of 10, Exceptional, (1000)
"Wonderful accommodations"
United States
Renee
The price is €111
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Place Evansville
Water park
Fairfield Inn By Marriott Evansville East

Fairfield Inn By Marriott Evansville East

Fairfield Inn By Marriott Evansville East
2.5 star property
Evansville
8.8 out of 10, Excellent, (459)
"Clean rooms friendly staff "
United States
Aleshia
The price is €82
includes taxes & fees
30 Dec - 31 Dec
Fairfield Inn By Marriott Evansville East
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (830)
"Clean, quiet and great location "
United States
Kristine
The price is €102
includes taxes & fees
11 Jan - 12 Jan 2026
Tempo By Hilton Louisville Downtown Nulu
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3881)
"Great place to stay! "
United States
Rochelle
The price is €133
includes taxes & fees
5 Jan - 6 Jan 2026
Galt House Hotel Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Indiana Hotel Reviews

Radisson Hotel Louisville North

Radisson Hotel Louisville North

10/10 Excellent
"Friendly staff. Great amenities. Easy access from Louisville via 2nd Street bridge. Nice clean rooms with plenty of pillows for maximum comfort. Even though I didn’t use the pool it is a nice size pool with plenty of room to just sit and relax. "
Brian 2-night trip
Posted 1 day ago
Radisson Hotel Louisville North

Frequently asked questions

How much do business-friendly hotels in Southern Indiana cost?
Business-friendly hotels in Southern Indiana range between €69 and €133 per night. This means you can book a property with welcome amenities like workspaces and conference rooms at a price that fits your work budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Indiana?
Southern Indiana offers multiple business-friendly hotels with a total average guest review rating of 8.7. Have a work event in Louisville? Residence Inn by Marriott Louisville East/Oxmoor is a 3-stars stay that's highly recommended by corporate travellers and features a barbecue grill and a swimming pool. Another popular pick for a business trip is Hilton Garden Inn Louisville Mall of St. Matthews. Also in Louisville, it has a 3-stars rating and conveniences such as an electric car charging station and a terrace.
How many business-friendly hotels are there in Southern Indiana?
When your next meeting or conference takes you someplace in Southern Indiana, you'll have 132 business-friendly hotels to pick from.
What are the best cheap business-friendly hotels in Southern Indiana?
When work is taking you out of town in Southern Indiana, Expedia will help you find the perfect business-friendly hotel. Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel is a sought-after budget option in Louisville. Hypo-allergenic bedding and an electric car charging station are among its many amenities. Seeking affordable stays in Evansville? Hampton Inn Evansville/Airport is the first choice for many corporate guests. It has conveniences that make it easy to both work and feel at home, such as pillow top mattresses and a swimming pool. Business-friendly hotels in Southern Indiana start at only €69 a night. There are tons of fabulous and free things to do wherever you're visiting in Southern Indiana. If your business trip is taking you to Louisville, try to find time in your schedule for Louisville Waterfront Park. You can also see the sights without spending a penny in Evansville. Bally's Evansville Casino is a popular free thing to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Southern Indiana?
Welcoming and affordable, motels are an ideal choice for your next business trip in Southern Indiana. If your job is taking you to Louisville, check out Days Inn by Wyndham Louisville Airport Fair and Expo Centre. It's around 11 kilometres south of the downtown area and includes amenities like individually decorated rooms and WiFi. Super 8 by Wyndham Louisville Airport also caters to the needs of corporate travellers. It has a nearby casino and WiFi and is located about 10 kilometres south of the centre of Louisville.Looking for epic things to do during your spare time in Louisville? Louisville Slugger Museum and Kentucky Kingdom are just two of the enticing attractions that'll capture your imagination.
Are there any family-friendly hotels in Southern Indiana that are also business friendly?
Absolutely. You'll find some great family-friendly hotels that are also business friendly in Southern Indiana. If you're travelling to Louisville, look up Residence Inn by Marriott Louisville East/Oxmoor. It includes amenities like complimentary breakfast and a barbecue grill and has a 3-stars rating. Another option worth considering is Hilton Garden Inn Louisville Mall of St. Matthews. This 3-stars stay in Louisville is ideal for both leisure and business travellers and features WiFi, laundry facilities and plenty more. You'll discover plenty of awesome things to do with your team in Louisville. Louisville Slugger Museum and Kentucky Kingdom deliver a great day out.
Are there any 5-star business-friendly hotels in Southern Indiana?
While there aren't any 5-star business-friendly hotels in Southern Indiana, there's still a selection of stylish properties to choose from. Visiting Louisville for work? Hotel Distil, Autograph Collection is a popular option that has everything you need and more when you're on a business trip. Amenities at this 4-star property include pillow top mattresses and dining romance packages. Omni Louisville Hotel is another great pick that caters to corporate guests in Louisville. Also with a 4-star rating and featuring spa facilities and massage services, you'll find plenty to love about this hotel.
Why book your business-friendly hotel in Southern Indiana with Expedia?
Expedia is here to help you find an ideal business-friendly hotel for your upcoming work trip. From conference spaces and room service to on-site cafés and more, our stays have all the amenities you'll need to get the job done.
How can I find cheap business-friendly hotels in Southern Indiana?
Select the "business friendly" filter, located under the "traveller experience" heading, to find cheap business-friendly hotels in Southern Indiana. Then narrow your search by your per-night budget. Choosing a stay away from the centre is another way to save.
What is there to do in Southern Indiana near my business-friendly hotel?
One of the most important travel accessories for your Southern Indiana business visit is a well-thought-out itinerary for when you have some free time! Louisville Slugger Museum, Louisville Waterfront Park and Louisville Palace are some of the most popular sights if you're making your way to Louisville. Evansville also offers lots of impressive attractions, such as Mesker Park Zoo, Evansville Museum of Arts, History & Science and Koch Family Children's Museum of Evansville.