Upstate South Carolina Guest Houses

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Upstate South Carolina guest houses

Private Suite in Downtown Simpsonville

Simpsonville

Jeanne M.

Outpost Inn

Highlands

Carol

includes taxes & fees

28 Jun - 29 Jun

Fletcher NC Getaway

Fletcher

Pamela R.

Cozy Mountain Cottage Near Downtown

Highlands

Katherine V.

includes taxes & fees

15 Jun - 16 Jun

Lakefront Mountain Cabin on Lake Glenville, NC

Glenville

"The property was beautiful and the hosts were very helpful! It was the perfect spot for a getaway with friends! The location was perfect as it was a short drive from town and right on a gorgeous lake, where we had access to canoes and kayaks. We went on a few gorgeous hikes around the area (Whiteside Mountain, High Falls, and Rainbow Fallls at Gorges National Park). I highly recommend staying here, and I can’t wait to book my next trip!"

Caroline L.

includes taxes & fees

17 Jun - 18 Jun

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Upstate South Carolina Hotel Reviews

Mint House Greenville Downtown by Kasa

6/10 Okay

"The room was very clean with one exception. We found cockroaches in the bathroom the first night. Management responded that they would treat the problem the next day. They did not. They did offer a 10% discount on another stay. Money off this stay would have been more appropriate. It’s unfortunate because the location was great. Probably would not return due to the pest issue not being resolved."

Lakeside Lodge Clemson

10/10 Excellent

"Pool was great, close to town. Room was well stocked with kitchen stuff. Loved the gym as well. One of the front desk employees was not very nice to a guest coming in. Room wasn't ready and he wasn't happy. She told him she couldn't help that staff had called in sick and they were short staffed. She had an ear bud in the whole time which is extremely rude."

Aloft by Marriott Greenville Downtown

8/10 Good

"Great location. Friendly helpful staff. Loved staying there. My only two negatives are the coffee served was very bitter so we went elsewhere every morning and in the evenings they had a DJ playing in the lobby/bar area which has a lot of hard surfaces that made it echo badly. Coming from a music & event background I’d suggest adding some sound absorbing elements to cut down on the cacophony."

Best Western Plus Clemson Hotel & Conference Center

6/10 Okay

"We were visiting the area for a college campus tour. The lobby and dining areas were clean and updated. Our room was not updated and the carpet was damp. The bathroom was very small. We had a hard time navigating the space with two people trying to get ready at the same time. The price was good, but I think we will stay elsewhere next time."

Find out more about Upstate South Carolina