Upstate South Carolina Hotels from €56 - Fully Refundable Options

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A pool area with lounge chairs and a sign for Best Western Plus.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

1. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

€76

includes taxes & fees

25 Oct - 26 Oct

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A golf course with multiple golf carts parked in a line.

Electric vehicle charging stations along a sidewalk with a building in the background.

An outdoor patio area with tables and chairs, a covered seating area, and a building in the background labeled "Embassy Suites."

2. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

€107

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio area with a fire feature, wicker furniture, and potted plants.

A Hilton Garden Inn with a central entrance, multiple floors, and a brick facade.

A row of Tesla electric vehicle charging stations.

3. Hilton Garden Inn Greenville

Greenville

Leroy

€99

includes taxes & fees

31 Oct - 1 Nov

A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.

A hotel room with a bed, a television, a window with curtains, and a wardrobe.

A compact living space with a kitchenette, a flat-screen TV, a sofa, and a bed with a patterned cover.

A room with a wall-mounted ATM, decorative wall panels, a window with red curtains, and a tiled floor.

4. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Greenville

Terry

€70

includes taxes & fees

1 Nov - 2 Nov

A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

A modern living room with a fireplace, a flat-screen TV, and comfortable seating.

A modern kitchen with a refrigerator, coffee machine, and various food items.

5. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Greenville

Lissette

€103

includes taxes & fees

15 Oct - 16 Oct

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A modern lobby with a blue sofa, a round coffee table, and a brown armchair.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A hotel room with two beds, a desk, a TV, and a patterned carpet.

6. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Jonathan

€87

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with hanging light fixtures and bar seating.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

A modern bar area with a central island, bar stools, and overhead lighting.

7. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jessica

€120

includes taxes & fees

1 Nov - 2 Nov

A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.

A snack bar with a variety of packaged foods and beverages, a refrigerated display case, and a counter with a sign that reads 'This and that and then some.'

A modern lobby with a blue sofa, teal armchairs, hanging lights, and a seating area with round chairs.

8. Tru by Hilton Greenville Woodruff Road

Greenville

semhar

€105

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

9. Drury Inn & Suites Greenville

Greenville

David

€113

includes taxes & fees

1 Nov - 2 Nov

A Comfort Suites hotel with a symmetrical facade, multiple windows, and a central entrance.

A hotel room with a bed, a sofa, two ottomans, a lamp, and three framed pictures on the wall.

An indoor swimming pool with clear lane markings, a sunroof, and lounge chairs along the poolside.

A spacious lobby with multiple seating areas, including sofas and chairs, and a reception desk.

10. Comfort Suites Piedmont - Greenville South

Piedmont

Stephanie

€91

includes taxes & fees

31 Oct - 1 Nov

A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.

A hotel room with a large bed, a television on a dresser, a nightstand with a lamp, and a window with curtains.

A cafe with a checkered floor, wooden cabinets, and hanging pendant lights.

A hotel pool area with lounge chairs, a flag, and a sunset view.

11. Hampton Inn Greenville I-385 - Woodruff Rd.

Greenville

Joseph

€103

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk, a chair, a wall-mounted lamp, and a painting.

A modern lobby with a reception desk, seating area, and a flat-screen TV mounted on the wall.

A hotel with a blue roof, palm trees, and a sign for the Clarion Inn.

A modern conference room with a long table, several chairs, a coffee station, and a kitchenette area.

12. Clarion Inn

Greenville

Mohamed Ayman

€72

includes taxes & fees

19 Oct - 20 Oct

A modern hotel room with a large bed, a separate bathroom with a bathtub, a nightstand, a lamp, and a wall-mounted artwork.

A reception area with two beige armchairs, a glass-top table, and a vibrant geometric wall art.

A spacious dining area with a central table and chairs, a kitchen in the background, and a sign indicating a breakfast area.

A reception desk with a stone facade, a peacock wall decoration, and a large potted plant.

13. Days Inn by Wyndham Greenville South/Mauldin

Mauldin

Terrence

€72

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A hotel lobby with a reception desk, computers, and a seating area.

A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.

14. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

George

€98

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, desk, chair, TV, and a wall with a framed picture.

A small, well-lit bathroom with a sink, mirror, and vanity. There is a towel rack on the wall and an air conditioning unit mounted above the mirror. The floor is tiled with a patterned design.

A small room with a round table, two chairs, a desk with a computer, a cabinet, and a framed picture on the wall.

A bathroom with a glass shower enclosure, a toilet, and a sink area.

15. Deluxe Inn

Mauldin

Amanda

€56

includes taxes & fees

28 Oct - 29 Oct

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A modern bar area with a wooden counter, a digital menu board, and a variety of liquor bottles.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

A modern lounge area with comfortable seating, a round table, and a large screen.

16. Courtyard by Marriott Greenville Mauldin

Greenville

Leticia

€108

includes taxes & fees

18 Oct - 19 Oct

A spacious hotel lobby with a central bar area, seating arrangements, and large windows providing natural light.

A conference room with a large flat-screen TV, multiple tables with chairs, and water bottles on each table.

A modern lounge area with green upholstered seating, a coffee table, and pendant lighting.

A modern kitchen with a bar area, a seating area with a sofa and chairs, and a television mounted on the wall.

17. Holiday Inn Greenville - Woodruff Road by IHG

Greenville

Diane

€108

includes taxes & fees

18 Oct - 19 Oct

A circular outdoor seating area with a fire pit, surrounded by sofas and chairs, in front of a multi-story building.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and landscaped garden.

A modern bar area with a curved counter, bar stools, and a wine glass.

A modern bar area with seating arrangements, a counter with various beverages, and a sports screen.

18. Courtyard by Marriott Greenville Haywood Mall

Greenville

Kimberly

€120

includes taxes & fees

25 Oct - 26 Oct

A spacious living area with a staircase, a sofa, a coffee table, and a desk with a chair.

A hotel room with a bed, a nightstand, a mirror, a sink, and framed pictures on the wall.

A hotel reception area with a wooden reception desk, a black rug, and a blue sofa.

19. Sleep Inn at Greenville Convention Cente

Greenville

Debra

€67

includes taxes & fees

8 Nov - 9 Nov

A covered outdoor area with a stone facade, a bench, and a truck parked nearby.

A modern office space with desks, chairs, a refrigerator stocked with beverages, and snack shelves.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a modern design and a fence.

A hotel reception area with a counter, computers, chairs, and a display case with pastries.

20. Comfort Inn Greenville - Haywood Mall

Greenville

Paul

€87

includes taxes & fees

18 Oct - 19 Oct

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Holiday Rentals in Upstate South Carolina

Aparthotel

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Aparthotel

A modern building with outdoor seating and a garden.

A row of modern, two-story buildings with a covered patio area.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A bed with a white quilted cover, flanked by two wall-mounted nightstands with lamps.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A kitchen with a wooden countertop, a sink, a coffee maker, a toaster, and a window with a view of trees.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cabin

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Beautiful cabin, attentive hosts, and an overall great stay. I would definitely go back."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Cottage

A playground with a swing set and a ladder.

A backyard with a gazebo, a fire pit, and a covered seating area.

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

A two-story house with a front porch, a small garden, and a wooden fence.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Apartment

A large house with a spacious driveway and a pond in the background.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

A modern kitchen with a central island, wooden cabinets, and a dining area with bar stools.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A round table with a white tablecloth, surrounded by chairs, set up for a meal.

A kitchen with granite countertops, stainless steel appliances, and dark wooden cabinets.

A spacious dining area with a large wooden table, surrounded by chairs, and a chandelier.

A living room with a fireplace, a television, a leather sofa, a red armchair, and a desk with drawers.

Stay at Jos Taylor Retreat: 9 Mi to Greenville!

Taylors

"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A modern kitchen with white cabinets, stainless steel appliances, and a patterned rug.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A white house with a sloped roof, surrounded by trees and a garden.

Clemson Game Day Cottage w/ Fire Pit

Clemson

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

8/10 Good

"Great stay… good full breakfast, comfortable room. Excellent, nice welcoming staff at front desk!"

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"My wife and I enjoyed our stay here. 10/10 experience."

Hyatt Place Greenville/Haywood

8/10 Good

"Room was good size and clean. Staff were helpful and welcoming. Construction was ongoing and they did their best to accommodate in spite of all the activity. It was a busy weekend and their elevators couldn't keep up. Overall not bad."

Hyatt Place Greenville Downtown

10/10 Excellent

"Excellent stay and great location downtown."

Clemson University's James F. Martin Inn

8/10 Good

"We had a nice brief stay at the inn the night before our tour at Clemson. There was a bit of an issue with parking due to there being an event at the center while we were staying there. Other than that, it was super convenient to the admissions/tour location and I would recommend it for anyone who was going for a tour at the University."

Aloft by Marriott Greenville Downtown

10/10 Excellent

"Super friendly staff! Great location to enjoy downtown Greenville."

Hotel Hartness

10/10 Excellent

"Beautiful property. Exceeded my expectations."

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

€70

1 Nov - 2 Nov

includes taxes & fees

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

€76

25 Oct - 26 Oct

includes taxes & fees

9.2/10 Wonderful! (1,593 reviews)

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

€87

18 Oct - 19 Oct

includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

€104

14 Oct - 15 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

€109

2 Nov - 3 Nov

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

€121

13 Oct - 14 Oct

includes taxes & fees

Explore a world of travel with Expedia

Greenville Holiday Rentals

Upstate South Carolina Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Best Western Plus Greenville I-385 Inn & Suites

2. Embassy Suites Greenville Golf Resort & Conference Center

3. Hilton Garden Inn Greenville

4. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

5. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

6. Fairfield Inn & Suites by Marriott Greenville Simpsonville

7. DoubleTree by Hilton Greenville Woodruff Road

8. Tru by Hilton Greenville Woodruff Road

9. Drury Inn & Suites Greenville

10. Comfort Suites Piedmont - Greenville South

11. Hampton Inn Greenville I-385 - Woodruff Rd.

12. Clarion Inn

13. Days Inn by Wyndham Greenville South/Mauldin

14. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

15. Deluxe Inn

16. Courtyard by Marriott Greenville Mauldin

17. Holiday Inn Greenville - Woodruff Road by IHG

18. Courtyard by Marriott Greenville Haywood Mall

19. Sleep Inn at Greenville Convention Cente

20. Comfort Inn Greenville - Haywood Mall

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

The Station by Compo Hotels

Carolina Camp Cedar

Claires Cottage ~ 4 Mi to Downtown Greenville!

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Clemson Memorabilia House

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greer Guest House < 1 Mi to Park & Downtown Area!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Stay at Jos Taylor Retreat: 9 Mi to Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Clemson Game Day Cottage w/ Fire Pit

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Hyatt Place Greenville/Haywood

Hyatt Place Greenville Downtown

Clemson University's James F. Martin Inn

Aloft by Marriott Greenville Downtown

Hotel Hartness

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

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