Upstate South Carolina Holidays

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville which includes autumn colours, a park and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Top hotels in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is €94 per night from 11 Jan to 12 Jan
€94
11 Jan - 12 Jan
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
Good

Reviewed on 2 Jan 2026

Hilton Greenville
Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown

3 out of 5
950 South Main Street Greenville SC
Fully refundableReserve now, pay when you stay
The price is €126 per night from 11 Jan to 12 Jan
€126
11 Jan - 12 Jan
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
The ladies in charge of breakfast (Michelle and Dana) are amazing and keep it stocked. Essence at the front desk really cares and checked in with us several times during our three-night stay.

Reviewed on 1 Jan 2026

Homewood Suites by Hilton Greenville Downtown
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
The price is €92 per night from 11 Jan to 12 Jan
€92
11 Jan - 12 Jan
includes taxes & fees
9/10 Wonderful! (1,023 reviews)
This is my 3rd stay and each time has been great. Excellent breakfast!

Reviewed on 4 Jan 2026

Embassy Suites Greenville Golf Resort & Conference Center
See all 2,930 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Falls Park on the Reedy

Falls Park on the Reedy

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

Falls Park on the Reedy
Fred W. Symmes Chapel

Fred W. Symmes Chapel

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the acclaimed theatre scene in this family-friendly area.

Bon Secours Wellness Arena

What to do in Upstate South Carolina

Epic City Scavenger Hunt in Garden Grove by Operation City Quest

Epic City Scavenger Hunt in Garden Grove by Operation City Quest

€9
per adult
Epic City Scavenger Hunt in Garden Grove by Operation City Quest
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

€30
per adult
Paranormal Walking Tour by Greenville Ghost Tours
See all activities in Upstate South Carolina

Frequently asked questions

Can I cancel my flight booking to Upstate South Carolina due to COVID-19?
Head to our Customer Service Portal for important information about changing or cancelling flights due to COVID-19. Make sure you also read through the terms and conditions of your chosen airline before booking your fare to Upstate South Carolina.
What's the best way to find cheap flights to Upstate South Carolina that have flexible change policies?
We understand that travel plans can change in the blink of an eye, so reserving a flexible ticket with Expedia is a sensible idea. Simply tick the "No change fee" box under the "Flexible change policies" filter. Your low-cost, flexible flight to Upstate South Carolina is just a few clicks away.
What are some of the general tips for travellers to Upstate South Carolina during the COVID-19 outbreak?
COVID-19 has affected how the world works in endless ways, and travel has changed with it. These tips will help you navigate these new challenges and prepare you for your trip to Upstate South Carolina:
  • Before booking anything, see if any travel bans or restrictions apply — in both your origin and destination. Get up-to-date information by reviewing government and travel websites.
  • Wear a face mask even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, place your pass on the scanner and then hold it up for inspection.
  • One container of liquid hand sanitizer is now allowed in your carry-on luggage. It must not be larger than 12 oz (350 ml), and you'll need to remove it from your bag for screening.
  • To reduce handling during screening, place items such as your phone and loose change into your carry-on rather than the bins.
  • Separate any food you're carrying for X-ray screening. Placing it in a clear plastic bag and into a bin reduces the need for a TSA officer to touch and inspect your belongings.

Which airlines fly to Upstate South Carolina?
Secure your ticket with American Airlines and then start piecing together your Upstate South Carolina itinerary. This leading carrier offers 19932 flights each month to Charlotte-Douglas Intl. Airport (CLT), a key gateway.
How can I find cheap tickets to Upstate South Carolina?
You'll always nab a fabulous deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred flight date, then check the flexible dates box above to see a list of prices for nearby days. was the lowest price for a flight to Upstate South Carolina in the last seven days.
How much is a flight to Upstate South Carolina?
One-way trips departing from () sold for as little as in the last seven days. During this period, the price of a round-trip fare to Upstate South Carolina ranged between and . If you find a bargain ticket, book as fast as you can — these prices don't stick around.
What are the most popular airports to fly into in Upstate South Carolina?
Book your flight to Charlotte-Douglas Intl. Airport (CLT) and experience everything that Upstate South Carolina has to offer. As the region's primary entry point, about 21666 flights touch down here every month.
When is the cheapest time to fly to Upstate South Carolina?
If you'd prefer to spend your hard-earned holiday money experiencing the delights of Upstate South Carolina rather than on your trip there, leave early in the week. The most affordable day to travel is normally Tuesday, with Monday coming in second. With many people travelling over the weekend, Saturday often has the costliest fares.
How much is a plane ticket to Upstate South Carolina?
Plane fares ranged anywhere from to in the last seven days. When you're ready to book, we'll help you find a low-cost flight to Upstate South Carolina.
Which airlines with flights to Upstate South Carolina employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, many airlines have introduced new rules and standards to help everybody get back in the skies. These carriers include:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.