Upstate South Carolina Holidays
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Where to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Nicholtown
If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.
West End
Visitors to West End like its restaurants and waterfalls, and Bi Lo Center is a sight worth a stop.
Overbrook Historic District
While Overbrook Historic District may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Beattie House and Bon Secours Wellness Arena.
Hampton-Pinckney Historic District
Hampton-Pinckney Historic District is well liked for its historical sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center.
Top hotels in Upstate South Carolina
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
€86
3 Sept - 4 Sept
includes taxes & fees
8.6/10 Excellent! (1,009 reviews)
"Tiny room, bathrooms were bland and not updated. Really 2 star quality , motel 6. Breakfast not included. The only good thing about this hotel is the large lobby. Front desk staff was not pleasant either"
Reviewed on 17 Aug 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
€78
31 Aug - 1 Sept
includes taxes & fees
8/10 Very good! (1,007 reviews)
"Great experience , staff was helpful and friendly"
Reviewed on 19 Aug 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
€149
6 Sept - 7 Sept
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
Photo by Karyn Thompson
Fred W. Symmes Chapel
9.8/10 (29 reviews)
You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
What to do in Upstate South Carolina
Paranormal Walking Tour by Greenville Ghost Tours
€30
per adult
Frequently asked questions
How much does a Upstate South Carolina holiday package cost?
From as low as . Yes, you read that right. Our Upstate South Carolina holiday packages are the best way to stretch your budget. Bundle your preferred hotels, flights and rental car and get to know this top destination.
How do I get a cheap travel package to Upstate South Carolina?
Our Upstate South Carolina holiday packages mean plenty of savings for the savvy explorer. For the best deal, simply combine your hotel, flights and extras (such as activities) into one neat package. But great bargains are only the start of your next awesome adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotels around the world to choose from. No matter your style, there's a package with your name on it.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the key things that draws people to Upstate South Carolina, so it makes perfect sense that many opt to stay in Greenville.
What are the top hotels in Upstate South Carolina?
When it comes to hotels in Greenville, Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall are two terrific options. If you're heading to Seneca, Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson will make you feel at home.
How far in advance should I book my Upstate South Carolina holiday?
While prices fluctuate, we generally suggest booking your seats as soon as possible. Most international airfares are available on Expedia up to 12 months in advance. If circumstances have left you booking late, you might still be in luck. Cheap journeys to Upstate South Carolina occasionally appear just weeks before departure.
What does an Expedia Upstate South Carolina travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your ideal Upstate South Carolina travel package. Once you've made your booking, you can add on the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the more dollars you'll save!
What should I know before booking a Upstate South Carolina travel package?
Design deals that suit your budget with an Expedia package. Hotels, flights, rental cars — we're a one-stop shop for all of them. You'll save big bucks just by bundling your bookings. Whether you're embarking on an adventure in the snow or getting some sun on a warm beach, your dream getaway is just a few clicks away.
Can I choose my airline with a Upstate South Carolina Expedia holiday package?
Yes — that's one of the best things about an Expedia holiday package. You can mix and match your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have lots of choice when putting together your Upstate South Carolina getaway.
If I'm not able to travel, can I cancel my Upstate South Carolina holiday package?
Yes, you can cancel your Upstate South Carolina booking if your plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
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- Flights to Greenville - Spartanburg
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- Flights from Greenville Downtown
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- Flights from Asheville (AVL) to Greenville (GMU)
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- 295 Sports Complex
- Anderson Holidays
- Bell Plaza Shopping Center
- Bon Secours Wellness Arena
- Cedar Lane Shopping Center
- Centre West Shopping Center
- Clemson Holidays
- Easley Skate Center
- Visit Easley
- Falls Park on the Reedy
- Fred W. Symmes Chapel
- Golden Lanes and Golden Skate
- Visit Greenville - Spartanburg
- Visit Greenville
- Hillandale Golf Course
- Honea Path Holidays
- Liberty Holidays
- Poinsett Bridge
- Roper Mountain Science Center
- Runway Park at GMU
- Starr Holidays
- Wade Hampton Mall Shopping Center
- Welcome Holidays
- Woodfin Ridge Golf Club
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
