Cheap Flights from Minneapolis - St. Paul to San Diego

View €86 flight on Tue, 2 Dec 2025Opens in a new window

Popular airlines from Minneapolis to San Diego

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Minneapolis - St. Paul to San Diego (MSP-SAN)

Prices were available within the past 7 days and start at €86 for one-way flights and €190 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€190 Return, found 1 day ago
€190
Return
found 1 day ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €190 found 1 day ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
CLD
Carlsbad
€216 Return, found 1 day ago
€216
Return
found 1 day ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to Carlsbad, returning Thu, 11 Sep, priced at €216 found 1 day ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€216 Return, found 1 day ago
€216
Return
found 1 day ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €216 found 1 day ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€242 Return, found 1 day ago
€242
Return
found 1 day ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €242 found 1 day ago
Delta
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€259 Return, found 1 day ago
€259
Return
found 1 day ago
Select Delta flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €259 found 1 day ago
United
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€275 Return, found 1 day ago
€275
Return
found 1 day ago
Select United flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €275 found 1 day ago

Find the cheapest month to fly from Minneapolis (MSP) to San Diego (SAN)

September is typically the cheapest month to fly

From €102 - €184 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.