Cheap Flights from Minneapolis - St. Paul to San Diego

View €127 flight on Fri, 5 Sep 2025Opens in a new window

Popular airlines from Minneapolis to San Diego

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Minneapolis - St. Paul to San Diego (MSP-SAN)

Prices were available within the past 7 days and start at €127 for one-way flights and €171 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€171 Return, found 5 days ago
€171
Return
found 5 days ago
Select Delta flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €171 found 5 days ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
CLD
Carlsbad
€187 Return, found 5 days ago
€187
Return
found 5 days ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to Carlsbad, returning Thu, 11 Sep, priced at €187 found 5 days ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€187 Return, found 5 days ago
€187
Return
found 5 days ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €187 found 5 days ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€213 Return, found 5 days ago
€213
Return
found 5 days ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €213 found 5 days ago
American Airlines
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€238 Return, found 5 days ago
€238
Return
found 5 days ago
Select American Airlines flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €238 found 5 days ago
United
Fri, 5 Sep - Thu, 11 Sep
MSP
Minneapolis
SAN
San Diego
€417 Return, found 5 days ago
€417
Return
found 5 days ago
Select United flight, departing Fri, 5 Sep from Minneapolis to San Diego, returning Thu, 11 Sep, priced at €417 found 5 days ago

Find the cheapest month to fly from Minneapolis (MSP) to San Diego (SAN)

September is typically the cheapest month to fly

From €102 - €180 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.