Cheap Flights from Prague to Southampton

View €183 flight on Mon, 18 Aug 2025Opens in a new window

Popular airlines from Prague to Southampton

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Prague to Southampton (PRG-SOU)

Prices were available within the past 7 days and start at €183 for one-way flights and €317 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Sun, 13 Jul - Thu, 17 Jul
PRG
Prague
SOU
Southampton
€317 Return, found 3 hours ago
€317
Return
found 3 hours ago
Select KLM flight, departing Sun, 13 Jul from Prague to Southampton, returning Thu, 17 Jul, priced at €317 found 3 hours ago
KLM
Sun, 13 Jul - Thu, 17 Jul
PRG
Prague
SOU
Southampton
€331 Return, found 3 hours ago
€331
Return
found 3 hours ago
Select KLM flight, departing Sun, 13 Jul from Prague to Southampton, returning Thu, 17 Jul, priced at €331 found 3 hours ago
KLM
Thu, 10 Jul - Mon, 14 Jul
PRG
Prague
SOU
Southampton
€346 Return, found 3 days ago
€346
Return
found 3 days ago
Select KLM flight, departing Thu, 10 Jul from Prague to Southampton, returning Mon, 14 Jul, priced at €346 found 3 days ago
KLM
Thu, 10 Jul - Mon, 14 Jul
PRG
Prague
SOU
Southampton
€362 Return, found 3 days ago
€362
Return
found 3 days ago
Select KLM flight, departing Thu, 10 Jul from Prague to Southampton, returning Mon, 14 Jul, priced at €362 found 3 days ago
KLM
Sun, 13 Jul - Thu, 17 Jul
PRG
Prague
SOU
Southampton
€372 Return, found 3 hours ago
€372
Return
found 3 hours ago
Select KLM flight, departing Sun, 13 Jul from Prague to Southampton, returning Thu, 17 Jul, priced at €372 found 3 hours ago
Aer Lingus
Thu, 10 Jul - Mon, 14 Jul
PRG
Prague
SOU
Southampton
€723 Return, found 3 days ago
€723
Return
found 3 days ago
Select Aer Lingus flight, departing Thu, 10 Jul from Prague to Southampton, returning Mon, 14 Jul, priced at €723 found 3 days ago
*Available to Expedia members.