Cheap flights from Santiago Metropolitan Region starting at €54

View €54 flight on Sun, 26 Oct 2025Opens in a new window

Popular airlines from Santiago Metropolitan Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Avianca

    Avianca

  • Sky Airlines

    Sky Airlines

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Aerolineas Argentinas

    Aerolineas Argentinas

  • B & H Airlines

    B & H Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Santiago Metropolitan Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Thu, 2 Oct - Wed, 8 Oct
SCL
Santiago
PUQ
Punta Arenas
€108 Return, found 4 days ago
€108
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 2 Oct from Santiago to Punta Arenas, returning Wed, 8 Oct, priced at €108 found 4 days ago
LATAM Airlines Group
Mon, 18 Aug - Mon, 25 Aug
SCL
Santiago
LIM
Lima
€140 Return, found 2 days ago
€140
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, 18 Aug from Santiago to Lima, returning Mon, 25 Aug, priced at €140 found 2 days ago
LATAM Airlines Group
Thu, 28 Aug - Sun, 31 Aug
SCL
Santiago
EZE
Buenos Aires
€182 Return, found 2 days ago
€182
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, 28 Aug from Santiago to Buenos Aires, returning Sun, 31 Aug, priced at €182 found 2 days ago
LATAM Airlines Group
Thu, 28 Aug - Sun, 31 Aug
SCL
Santiago
AEP
Buenos Aires
€186 Return, found 2 days ago
€186
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, 28 Aug from Santiago to Buenos Aires, returning Sun, 31 Aug, priced at €186 found 2 days ago
Aerolineas Argentinas
Sat, 20 Dec - Tue, 23 Dec
SCL
Santiago
EZE
Buenos Aires
€207 Return, found 4 days ago
€207
Return
found 4 days ago
Select Aerolineas Argentinas flight, departing Sat, 20 Dec from Santiago to Buenos Aires, returning Tue, 23 Dec, priced at €207 found 4 days ago
LATAM Airlines Group
Tue, 17 Mar - Wed, 25 Mar
SCL
Santiago
GRU
Sao Paulo
€220 Return, just found
€220
Return
just found
Select LATAM Airlines Group flight, departing Tue, 17 Mar from Santiago to Sao Paulo, returning Wed, 25 Mar, priced at €220 just found
Turkish Airlines
Fri, 26 Sep - Sun, 28 Sep
SCL
Santiago
GRU
Sao Paulo
€224 Return, found 4 days ago
€224
Return
found 4 days ago
Select Turkish Airlines flight, departing Fri, 26 Sep from Santiago to Sao Paulo, returning Sun, 28 Sep, priced at €224 found 4 days ago
KLM
Thu, 28 Aug - Sun, 31 Aug
SCL
Santiago
EZE
Buenos Aires
€256 Return, found 2 days ago
€256
Return
found 2 days ago
Select KLM flight, departing Thu, 28 Aug from Santiago to Buenos Aires, returning Sun, 31 Aug, priced at €256 found 2 days ago
Delta
Mon, 1 Sep - Sun, 14 Sep
SCL
Santiago
MIA
Miami
€403 Return, found 2 days ago
€403
Return
found 2 days ago
Select Delta flight, departing Mon, 1 Sep from Santiago to Miami, returning Sun, 14 Sep, priced at €403 found 2 days ago
Copa
Mon, 1 Sep - Sun, 14 Sep
SCL
Santiago
MIA
Miami
€467 Return, found 2 days ago
€467
Return
found 2 days ago
Select Copa flight, departing Mon, 1 Sep from Santiago to Miami, returning Sun, 14 Sep, priced at €467 found 2 days ago
*Available to Expedia members.