Cheap flights from Santa Cruz starting at €249

View €249 flight on Thu, 5 Feb 2026Opens in a new window

Popular airlines from Santa Cruz

  • Avianca

    Avianca

  • LATAM Airlines Group

    LATAM Airlines Group

  • Boliviana De Aviacion

    Boliviana De Aviacion

  • Copa

    Copa

  • GOL Linhas Aereas S.A.

    GOL Linhas Aereas S.A.

  • United

    United

  • Air Europa

    Air Europa

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Cheapest flights from Santa Cruz

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Fri, 9 Jan - Fri, 16 Jan
VVI
Santa Cruz
PTY
Panama City
€869 Return, found 19 hours ago
€869
Return
found 19 hours ago
Select avianca flight, departing Fri, 9 Jan from Santa Cruz to Panama City, returning Fri, 16 Jan, priced at €869 found 19 hours ago
avianca
Fri, 9 Jan - Fri, 16 Jan
VVI
Santa Cruz
PTY
Panama City
€929 Return, found 19 hours ago
€929
Return
found 19 hours ago
Select avianca flight, departing Fri, 9 Jan from Santa Cruz to Panama City, returning Fri, 16 Jan, priced at €929 found 19 hours ago
Air Europa
Sat, 11 Apr - Sat, 25 Apr
VVI
Santa Cruz
MAD
Madrid
€954 Return, found 3 days ago
€954
Return
found 3 days ago
Select Air Europa flight, departing Sat, 11 Apr from Santa Cruz to Madrid, returning Sat, 25 Apr, priced at €954 found 3 days ago
avianca
Fri, 9 Jan - Fri, 16 Jan
VVI
Santa Cruz
PTY
Panama City
€967 Return, found 19 hours ago
€967
Return
found 19 hours ago
Select avianca flight, departing Fri, 9 Jan from Santa Cruz to Panama City, returning Fri, 16 Jan, priced at €967 found 19 hours ago
Boliviana De Aviacion
Sat, 11 Apr - Sat, 25 Apr
VVI
Santa Cruz
MAD
Madrid
€1,007 Return, found 3 days ago
€1,007
Return
found 3 days ago
Select Boliviana De Aviacion flight, departing Sat, 11 Apr from Santa Cruz to Madrid, returning Sat, 25 Apr, priced at €1,007 found 3 days ago
avianca
Fri, 9 Jan - Fri, 16 Jan
VVI
Santa Cruz
PTY
Panama City
€1,027 Return, found 19 hours ago
€1,027
Return
found 19 hours ago
Select avianca flight, departing Fri, 9 Jan from Santa Cruz to Panama City, returning Fri, 16 Jan, priced at €1,027 found 19 hours ago
Air Europa
Sat, 11 Apr - Sat, 25 Apr
VVI
Santa Cruz
MAD
Madrid
€1,062 Return, found 3 days ago
€1,062
Return
found 3 days ago
Select Air Europa flight, departing Sat, 11 Apr from Santa Cruz to Madrid, returning Sat, 25 Apr, priced at €1,062 found 3 days ago
Boliviana De Aviacion
Sat, 11 Apr - Sat, 25 Apr
VVI
Santa Cruz
MAD
Madrid
€1,062 Return, found 3 days ago
€1,062
Return
found 3 days ago
Select Boliviana De Aviacion flight, departing Sat, 11 Apr from Santa Cruz to Madrid, returning Sat, 25 Apr, priced at €1,062 found 3 days ago
Boliviana De Aviacion
Sat, 11 Apr - Sat, 25 Apr
VVI
Santa Cruz
MAD
Madrid
€1,098 Return, found 3 days ago
€1,098
Return
found 3 days ago
Select Boliviana De Aviacion flight, departing Sat, 11 Apr from Santa Cruz to Madrid, returning Sat, 25 Apr, priced at €1,098 found 3 days ago
Copa
Fri, 9 Jan - Fri, 16 Jan
VVI
Santa Cruz
PTY
Panama City
€1,118 Return, found 19 hours ago
€1,118
Return
found 19 hours ago
Select Copa flight, departing Fri, 9 Jan from Santa Cruz to Panama City, returning Fri, 16 Jan, priced at €1,118 found 19 hours ago

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