Photo by Krystalene Clough

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to McGhee Tyson Airport (TYS)
- American Airlines
American Airlines
- Delta
Delta
- United
United
- Frontier Airlines
Frontier Airlines
- Plan, book, fly with confidence
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Cheap flights from Buffalo to Knoxville (BUF-TYS)
Prices were available within the past 7 days and start at €206 for one-way flights and €265 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€265 Return, found 4 hours ago
€265
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€291 Return, found 4 hours ago
€291
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€312 Return, found 4 hours ago
€312
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€315 Return, found 4 hours ago
€315
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€325 Return, found 4 hours ago
€325
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€332 Return, found 4 hours ago
€332
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€338 Return, found 4 hours ago
€338
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€342 Return, found 4 hours ago
€342
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€351 Return, found 4 hours ago
€351
Return
found 4 hours ago

Fri, 7 Nov - Mon, 17 Nov
BUF
Buffalo
TYS
Knoxville
€620 Return, found 4 hours ago
€620
Return
found 4 hours ago
Origin airport | Buffalo Niagara Intl. |
Destination airport | McGhee Tyson |
Airlines serving | American Airlines, Delta, United |
Return price | €264 |
Distance | 906 km |
Perfect flights from Buffalo to Knoxville
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Buffalo to Knoxville. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible Buffalo Niagara Intl. to McGhee Tyson ticket options cater to your travel preferences, with incredible one-way fares from €206 and roundtrip prices from €265. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at McGhee Tyson and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Knoxville.
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