€292 Cheap Flights Panama City to Santa Cruz (PTY-VVI)

View €292 flight on Sat, 23 May 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Santa Cruz (VVI-Viru Viru Intl.)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 15% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Panama City to Santa Cruz (PTY-VVI)

Prices were available within the past 7 days and start at €292 for one-way flights and €572 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€572 Return, found 5 days ago
€572
Return
found 5 days ago
Select avianca flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €572 found 5 days ago
avianca
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€575 Return, found 3 days ago
€575
Return
found 3 days ago
Select avianca flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €575 found 3 days ago
Copa
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€591 Return, found 5 days ago
€591
Return
found 5 days ago
Select Copa flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €591 found 5 days ago
Copa
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€686 Return, found 3 days ago
€686
Return
found 3 days ago
Select Copa flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €686 found 3 days ago
avianca
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€718 Return, found 5 days ago
€718
Return
found 5 days ago
Select avianca flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €718 found 5 days ago
avianca
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€720 Return, found 3 days ago
€720
Return
found 3 days ago
Select avianca flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €720 found 3 days ago
Copa
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€727 Return, found 5 days ago
€727
Return
found 5 days ago
Select Copa flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €727 found 5 days ago
avianca
Wed, 23 Dec - Sun, 14 Feb
PTY
Panama City
VVI
Santa Cruz
€766 Return, found 2 days ago
€766
Return
found 2 days ago
Select avianca flight, departing Wed, 23 Dec from Panama City to Santa Cruz, returning Sun, 14 Feb, priced at €766 found 2 days ago
Copa
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€823 Return, found 3 days ago
€823
Return
found 3 days ago
Select Copa flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €823 found 3 days ago
Copa
Wed, 23 Dec - Sun, 14 Feb
PTY
Panama City
VVI
Santa Cruz
€869 Return, found 2 days ago
€869
Return
found 2 days ago
Select Copa flight, departing Wed, 23 Dec from Panama City to Santa Cruz, returning Sun, 14 Feb, priced at €869 found 2 days ago
avianca
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€966 Return, found 5 days ago
€966
Return
found 5 days ago
Select avianca flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €966 found 5 days ago
avianca
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€968 Return, found 3 days ago
€968
Return
found 3 days ago
Select avianca flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €968 found 3 days ago
Copa
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€1,022 Return, found 5 days ago
€1,022
Return
found 5 days ago
Select Copa flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €1,022 found 5 days ago
Copa
Mon, 22 Jun - Sun, 28 Jun
PTY
Panama City
VVI
Santa Cruz
€1,025 Return, found 3 days ago
€1,025
Return
found 3 days ago
Select Copa flight, departing Mon, 22 Jun from Panama City to Santa Cruz, returning Sun, 28 Jun, priced at €1,025 found 3 days ago
Copa
Wed, 23 Dec - Sun, 14 Feb
PTY
Panama City
VVI
Santa Cruz
€1,074 Return, found 2 days ago
€1,074
Return
found 2 days ago
Select Copa flight, departing Wed, 23 Dec from Panama City to Santa Cruz, returning Sun, 14 Feb, priced at €1,074 found 2 days ago
Copa
Sat, 23 May - Fri, 29 May
PTY
Panama City
VVI
Santa Cruz
€1,089 Return, found 5 days ago
€1,089
Return
found 5 days ago
Select Copa flight, departing Sat, 23 May from Panama City to Santa Cruz, returning Fri, 29 May, priced at €1,089 found 5 days ago

Frequently asked questions

How much is a flight from Panama Airport to Viru Viru Intl. Airport (VVI)?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price available for a round-trip journey from PTY to Viru Viru was €572. Fares this cheap don't hang around, so book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Tocumen Intl. Airport (PTY) to VVI?
Every air carrier has its own terms and conditions. If you do decide to cancel, follow the easy instructions on our Customer Service Portal.
How do I find cheap flights from Tocumen Intl. Airport (PTY) to VVI that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to VVI flights, you'll see a "no change fees" filter for you to select.
How far is the flight from PTY to Viru Viru?
It's around 3,500 kilometres between Tocumen and Santa Cruz, so expect to be flying for a while. Keep yourself occupied with things like playing cards (if you're travelling with friends) or the latest bestseller.
Which airlines fly direct from PTY to VVI?
If you want to fly directly from PTY to VVI, Copa Airlines (CM) is a great option. It operates 47 flights every month between Tocumen and Santa Cruz.
Are Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) flight tickets cheaper when they're purchased at the last minute?
It is possible to find an awesome last-minute deal from PTY to VVI, but it's also possible to miss out entirely! As many airlines release prices up to a year in advance, it's worth keeping an eye on fares early and being ready to pounce when you see a good bargain. Expedia compares air carrier prices and updates flight deals frequently, so you can feel confident knowing you're always getting the latest offers.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Viru Viru Intl.
Return price
€572
Distance
3445 km
Average flight time
5 hours 59 mins

Explore a world of travel with Expedia

*Available to Expedia members.