€295 Cheap Flights Rome to San Francisco (ROM-SFO)

View €295 flight on Tue, 2 Sep 2025Opens in a new window

Popular airlines from Rome to San Francisco, CA (SFO-San Francisco Intl.)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Rome to San Francisco (ROM-SFO)

Prices were available within the past 7 days and start at €295 for one-way flights and €418 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Fri, 13 Feb - Fri, 20 Feb
FCO
Rome
SFO
San Francisco
€418 Return, found 5 days ago
€418
Return
found 5 days ago
Select TAP Portugal flight, departing Fri, 13 Feb from Rome to San Francisco, returning Fri, 20 Feb, priced at €418 found 5 days ago
Condor
Mon, 8 Sep - Tue, 23 Sep
FCO
Rome
SFO
San Francisco
€420 Return, found 3 days ago
€420
Return
found 3 days ago
Select Condor flight, departing Mon, 8 Sep from Rome to San Francisco, returning Tue, 23 Sep, priced at €420 found 3 days ago
ITA Airways
Mon, 8 Sep - Tue, 23 Sep
FCO
Rome
SFO
San Francisco
€539 Return, found 3 days ago
€539
Return
found 3 days ago
Select ITA Airways flight, departing Mon, 8 Sep from Rome to San Francisco, returning Tue, 23 Sep, priced at €539 found 3 days ago
United
Tue, 7 Oct - Sun, 12 Oct
FCO
Rome
SFO
San Francisco
€570 Return, found 8 hours ago
€570
Return
found 8 hours ago
Select United flight, departing Tue, 7 Oct from Rome to San Francisco, returning Sun, 12 Oct, priced at €570 found 8 hours ago
Lufthansa
Tue, 7 Oct - Sun, 12 Oct
FCO
Rome
SFO
San Francisco
€570 Return, found 8 hours ago
€570
Return
found 8 hours ago
Select Lufthansa flight, departing Tue, 7 Oct from Rome to San Francisco, returning Sun, 12 Oct, priced at €570 found 8 hours ago
Scandinavian Airlines
Mon, 8 Sep - Tue, 23 Sep
FCO
Rome
SFO
San Francisco
€571 Return, found 3 days ago
€571
Return
found 3 days ago
Select Scandinavian Airlines flight, departing Mon, 8 Sep from Rome to San Francisco, returning Tue, 23 Sep, priced at €571 found 3 days ago
Swiss International Air Lines
Tue, 7 Oct - Sun, 12 Oct
FCO
Rome
SFO
San Francisco
€580 Return, found 8 hours ago
€580
Return
found 8 hours ago
Select Swiss International Air Lines flight, departing Tue, 7 Oct from Rome to San Francisco, returning Sun, 12 Oct, priced at €580 found 8 hours ago
Air Canada
Tue, 7 Oct - Sun, 12 Oct
FCO
Rome
SFO
San Francisco
€583 Return, found 8 hours ago
€583
Return
found 8 hours ago
Select Air Canada flight, departing Tue, 7 Oct from Rome to San Francisco, returning Sun, 12 Oct, priced at €583 found 8 hours ago
Aer Lingus
Tue, 7 Oct - Sun, 12 Oct
FCO
Rome
SFO
San Francisco
€585 Return, found 8 hours ago
€585
Return
found 8 hours ago
Select Aer Lingus flight, departing Tue, 7 Oct from Rome to San Francisco, returning Sun, 12 Oct, priced at €585 found 8 hours ago
American Airlines
Thu, 28 Aug - Sat, 13 Sep
FCO
Rome
SFO
San Francisco
€588 Return, found 1 day ago
€588
Return
found 1 day ago
Select American Airlines flight, departing Thu, 28 Aug from Rome to San Francisco, returning Sat, 13 Sep, priced at €588 found 1 day ago

Find the cheapest month to fly from Rome (ROM) to San Francisco (SFO)

January is typically the cheapest month to fly

From €390 - €916 per traveller.

Graph displaying average flight prices per month

Rome to San Francisco route information
Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Condor, Delta, Emirates, Finnair, ITA Airways, Iberia, KLM, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Turkish Airlines, United
Return price
€418
Distance
10000 km

Lazio to San Francisco Flights

When looking for plane tickets from Lazio to San Francisco, the ease and convenience of using Expedia simply can’t be beat. With tons of departure points and flights options from the top airline carriers, Expedia gives you the widest array of cheap flights to San Francisco. Look for ROM to SFO airfare with the assurance that you have the largest online travel agency working for you.

Expedia lets you search across the largest number of airlines and San Francisco flights, which means that you’ll be able to find a great flight deal at the perfect travel date and time. Our simple-to-use booking engine makes looking for terrific bargains easy and hassle-free; just enter your travel dates and departure city, and let Expedia do the rest! Adjust your travel dates and explore connecting flights to find an even better deal on your Lazio San Francisco flight!

Browse through dozens of options and rest assured that you’re seeing the best price guaranteed! Our friendly customer service representatives are here to serve you 24 hours day to provide assistance and answer any questions that you may have about booking your Lazio to San Francisco trip. There’s simply no substitute for great prices suited to your travel needs and backed by excellent customer support.

Combine your San Francisco flight with a hotel and/or car rental for a package deal designed to save you even more money! Discover additional savings by booking in advance or find a last minute deal. There are tons of ways to save on your flights from Lazio to San Francisco with Expedia. Use us as your stop travel destination and have the confidence that you’re getting a bargain!

Frequently asked questions

How much is a flight from Rome (ROM-All Airports) to San Francisco Intl. Airport (SFO)?
The lowest price advertised for a round-trip journey between Rome (ROM-All Airports) and San Francisco Intl. Airport (SFO) is €418. But you better act soon. This figure is based on fares listed within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Rome (ROM-All Airports) to San Francisco Airport?
We understand that things crop up unexpectedly, so we've made it as simple as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.
How do I find cheap flights from Rome (ROM-All Airports) to San Francisco Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Rome (ROM-All Airports) to SFO flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Rome (ROM-All Airports) to San Francisco Intl. Airport (SFO)?
Province of Rome to San Francisco is around 10,100 kilometres, so get ready to spend quite a while in the air. Don't forget to pack all the essentials, from your toothbrush to your hairbrush. Toss in some snacks to nibble on throughout your flight too.
Which airlines fly direct from Rome (ROM-All Airports) to SFO?
Flying directly between Rome (ROM-All Airports) and San Francisco Intl. Airport (SFO) isn't possible at present. However, you'll still be able to book a flight to San Francisco with at least one stop.
Are Rome (ROM-All Airports) to SFO flight tickets cheaper when they're purchased at the last minute?
It is possible to get great last-minute deals from Rome (ROM-All Airports) to San Francisco Airport, but there's no guarantee. As many airlines publish prices up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to pounce when you spot a good bargain. Expedia compares carrier prices and updates flight deals all the time, so you can rest easy knowing you're always seeing the latest offers.

Explore a world of travel with Expedia

*Available to Expedia members.