4 Star Hotels in Big Pine Key, Florida

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Top Big Pine Key 4 Star Hotels

Tranquility Bay Beachfront Hotel and Resort

4.0 star property
Marathon
8.8 out of 10, Excellent, (1006)
"Lives up to its name. Very relaxing and low key. Had a lovely stay with friendly staff."
United States
Elizabeth
The price is €288
includes taxes & fees
1 Dec - 2 Dec
Tranquility Bay Beachfront Hotel and Resort

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4.0 star property
Marathon
8.8 out of 10, Excellent, (1276)
"Great place to stay, extremely pet friendly for those like me who want to travel with their pets. "
United States
James
The price is €172
includes taxes & fees
17 Nov - 18 Nov
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Marlin Bay Resort & Marina

4.0 star property
Marathon
Marlin Bay Resort & Marina

The Reef at Marathon, Florida Keys

4.0 star property
Marathon
9.4 out of 10, Exceptional, (8)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."
United States
Michelle
The Reef at Marathon, Florida Keys

Key Colony Beach Paradise

4.0 star property
Coury
10.0 out of 10, Exceptional, (4)
"We loved this property. The boat dock is so large and we really appreciate the bumpers to protect the boat. Plenty of seating around the pool. The afternoon sun really heats that side of the street so the pool was very warm - still refreshing. The beds are super comfortable and the house is laid out very well with plenty of room. We loved our stay!!!"
United States
Rachel T.
Key Colony Beach Paradise

Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

4.0 star property
Key Colony Beach
Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

4.0 star property
Pine Channel Estates
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

4.0 star property
Marathon Shores
Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

Indigo Reef Marina Homes by Pack and Relax

4.0 star property
Marathon
Indigo Reef Marina Homes by Pack and Relax

Indigo Reef Marina Pet Friendly Homes by Pack and Relax

4.0 star property
Marathon
Indigo Reef Marina Pet Friendly Homes by Pack and Relax
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard, MM 47, Marathon, FL
The price is €313 per night from 18 Nov to 19 Nov
€313
18 Nov - 19 Nov
includes taxes & fees
9/10 Wonderful! (1,049 reviews)
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Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

Bahia Honda State Park showing general coastal views, a bridge and a beach

Top Big Pine Key Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Big Pine Key?
Create unforgettable holiday memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. A favourite with our guests, this 4-star hotel offers loads of conveniences for a relaxing and comfortable stay.
How much does it cost to stay in a 4-star hotel in Big Pine Key?
To find a 4-star hotel in Big Pine Key that fits your budget, use Expedia's handy filters. Take a look at the available options during your holiday dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly stay first.

  • Search for the lowest price from €313

What's the difference between 5-star and 4-star hotels in Big Pine Key?
Treat yourself to luxury living during your Big Pine Key getaway by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are usually packed with amenities like large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and unforgettable one. 24-hour concierge assistance, elegant furnishings and world-class dining are only the start of the exclusive services and conveniences you'll likely have access to.