4 Star Hotels in Big Pine Key, Florida

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Top Big Pine Key 4 Star Hotels

Our top choices for Big Pine Key 4-star hotels

Tranquility Bay Beachfront Hotel and Resort

4.0 star property
8.8 out of 10, Excellent, (1001)
"Amazing stay, our second time here and we love it, never fails when you need a relaxing and quiet get away! "
The price is €254
includes taxes & fees
15 Oct - 16 Oct
Tranquility Bay Beachfront Hotel and Resort

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4.0 star property
8.8 out of 10, Excellent, (1278)
"Great stay "
The price is €178
includes taxes & fees
1 Oct - 2 Oct
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Marlin Bay Resort & Marina

4.0 star property
Marlin Bay Resort & Marina

The Reef at Marathon, Florida Keys

4.0 star property
9.4 out of 10, Exceptional, (8)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."
The Reef at Marathon, Florida Keys

Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

4.0 star property
Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

Key Colony Beach Paradise

4.0 star property
10.0 out of 10, Exceptional, (4)
Key Colony Beach Paradise

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

4.0 star property
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

4.0 star property
Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

Indigo Reef Marina Homes by Pack and Relax

4.0 star property
Indigo Reef Marina Homes by Pack and Relax

Indigo Reef Marina Pet Friendly Homes by Pack and Relax

4.0 star property
Indigo Reef Marina Pet Friendly Homes by Pack and Relax
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard, MM 47, Marathon, FL
The price is €272 per night from 28 Sept to 29 Sept
€272
28 Sept - 29 Sept
includes taxes & fees
9/10 Wonderful! (1,063 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Meet the local wildlife, splash in the shallows and enjoy the calm of the quieter Keys on this stretch of serene waterfront and wetlands.

Big Pine Key which includes general coastal views, a bay or harbour and a coastal town

Top Big Pine Key Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Big Pine Key?
Create unforgettable holiday memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. A favourite with our guests, this 4-star hotel offers loads of conveniences for a relaxing and comfortable stay.
How much does it cost to stay in a 4-star hotel in Big Pine Key?
To find a 4-star hotel in Big Pine Key that fits your budget, use Expedia's handy filters. Take a look at the available options during your holiday dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly stay first.

  • Search for the lowest price from €272

What's the difference between 5-star and 4-star hotels in Big Pine Key?
Treat yourself to luxury living during your Big Pine Key getaway by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are usually packed with amenities like large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and unforgettable one. 24-hour concierge assistance, elegant furnishings and world-class dining are only the start of the exclusive services and conveniences you'll likely have access to.