4 Star Hotels in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
7 Aug - 8 Aug
Tomorrow
8 Aug - 9 Aug
This weekend
8 Aug - 10 Aug
Next weekend
15 Aug - 17 Aug

Top Upstate South Carolina 4 Star Hotels

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (369)
"The property have an incredible view to the river. "
The price is €228
includes taxes & fees
1 Sept - 2 Sept
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville
Meeting facility

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Location is probably the best in the city "
The price is €169
includes taxes & fees
17 Aug - 18 Aug
The Westin Poinsett Greenville
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (653)
"This was a phenomenal place to stay in downtown Clemson. We will definitely be back! "
The price is €170
includes taxes & fees
1 Sept - 2 Sept
The Shepherd Hotel Downtown Clemson
Hotel Hartness
Restaurant

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (575)
"Beautiful property and attentive staff. "
The price is €197
includes taxes & fees
10 Aug - 11 Aug
Hotel Hartness
Greenville Marriott
1 bedroom, premium bedding, down duvets, pillow-top beds

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (584)
"The staff was excellent and the facility was user friendly"
The price is €125
includes taxes & fees
17 Aug - 18 Aug
Greenville Marriott
Mint House Greenville - Downtown
Apartment, 2 Bedrooms

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (708)
"Will definitely stay again!"
The price is €104
includes taxes & fees
17 Aug - 18 Aug
Mint House Greenville - Downtown
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (537)
"Big rooms, convenient parking, quiet. I would stay again in a heartbeat! "
The Abernathy of Clemson
Park Place Apartments by Landing
Apartment, 2 Bedrooms | Living area

Park Place Apartments by Landing

4.0 star property
7.8 out of 10, Good, (37)
"The concept is nice, but the execution/completion would make it nicer. Power went out for over 32 hrs (not sure if it was longer because I left for better accomodations), alarms went off, there is no alternative to the steep stairs due to the elevators not being complete. It was cool for the few hours I had power. "
Park Place Apartments by Landing
Liberty Hall Bed and Breakfast
Restaurant

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (68)
"Wonderful experience all around! Breakfast was amazing each morning Host was attentive and friendly, going above and beyond to find out a little about us to make our stay extra special. "
The price is €164
includes taxes & fees
22 Aug - 23 Aug
Liberty Hall Bed and Breakfast
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (8)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is €257
includes taxes & fees
10 Aug - 11 Aug
The Station by Compo Hotels
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is €395
includes taxes & fees
24 Aug - 25 Aug
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is €390
includes taxes & fees
10 Aug - 11 Aug
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Terrace/patio

Belvedere

4.0 star property
8.0 out of 10, Very good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
34 Allen St
Stovetop, dishwasher, coffee/tea maker, toaster

34 Allen St

4.0 star property
34 Allen St
Randall St , 202/204
House (202 / 204 Randall St Full Duplex) | Private kitchen

Randall St , 202/204

4.0 star property
Randall St , 202/204
140 Catlin Circle
House | Exterior

140 Catlin Circle

4.0 star property
140 Catlin Circle
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg featuring mountains, views and a sunset
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"This property was as close to flawless as could be. Comfortable at every nook while also having so much in the way of art."
Ashley 1-night trip
Posted 3 days ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.