4 Star Hotels in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina 4 Star Hotels

Top Upstate South Carolina 4 Star Hotels

Our top choices for Upstate South Carolina 4-star hotels

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (378)
"We had a great stay. Beautiful lodge and walkable setting. "
The price is €227
includes taxes & fees
14 Sept - 15 Sept
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville
Meeting facility

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Beautiful old hotel. Liked that it was downtown in a nice neighborhood for strolling. Friendly and very helpful management. "
The price is €177
includes taxes & fees
7 Sept - 8 Sept
The Westin Poinsett Greenville
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (667)
"Fantastic high-end hotel with great amenities, service and convenience!"
The price is €170
includes taxes & fees
1 Sept - 2 Sept
The Shepherd Hotel Downtown Clemson
Greenville Marriott
1 bedroom, premium bedding, down duvets, pillow-top beds

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (587)
"The staff was excellent and the facility was user friendly"
The price is €124
includes taxes & fees
31 Aug - 1 Sept
Greenville Marriott
Mint House Greenville - Downtown
Apartment, 2 Bedrooms

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (720)
"Highly recommend this place…it’s especially great for families or groups. "
The price is €112
includes taxes & fees
14 Sept - 15 Sept
Mint House Greenville - Downtown
Hotel Hartness
Restaurant

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (579)
"Beautiful property and attentive staff. "
The price is €188
includes taxes & fees
31 Aug - 1 Sept
Hotel Hartness
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (539)
"Customer service was above and beyond, whenever we travel through Clemson again, we will only stay at The Abernathy!"
The Abernathy of Clemson
Park Place Apartments by Landing
Apartment, 2 Bedrooms | Living area

Park Place Apartments by Landing

4.0 star property
7.8 out of 10, Good, (37)
"Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge. "
Park Place Apartments by Landing
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (12)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is €255
includes taxes & fees
28 Aug - 29 Aug
The Station by Compo Hotels
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is €431
includes taxes & fees
2 Sept - 3 Sept
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
34 Allen St
Stovetop, dishwasher, coffee/tea maker, toaster

34 Allen St

4.0 star property
34 Allen St
140 Catlin Circle
House | Exterior

140 Catlin Circle

4.0 star property
140 Catlin Circle
Randall St , 202/204
House (202 / 204 Randall St Full Duplex) | Private kitchen

Randall St , 202/204

4.0 star property
Randall St , 202/204
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg featuring mountains, views and a sunset
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

Explore a world of travel with Expedia

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Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from €112

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.