Photo by Michelle Hendrix

4 Star Hotels in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
24 Nov - 25 Nov
Tomorrow
25 Nov - 26 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Upstate South Carolina 4 Star Hotels

Lobby
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (409)
"The staff were really sweet and responsive. The views from the rooms are breathtaking! "
United States
Krystal
The price is €264
includes taxes & fees
30 Nov - 1 Dec
Grand Bohemian Lodge Greenville, Autograph Collection
Meeting facility
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1003)
"Room was much smaller than other Westin's but great location and friendly staff"
United States
Aanal
The price is €161
includes taxes & fees
24 Dec - 25 Dec
The Westin Poinsett Greenville
In-room safe, blackout curtains, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4.0 star property
Clemson
9.8 out of 10, Exceptional, (728)
"Wonderful staff, great location"
United States
Shelly
The price is €163
includes taxes & fees
8 Dec - 9 Dec
The Shepherd Hotel Downtown Clemson
Restaurant
Hotel Hartness

Hotel Hartness

4.0 star property
Greenville
9.8 out of 10, Exceptional, (617)
"Excellent staff and facilities. Very clean, comfortable and welcoming atmosphere and very enjoyable stay"
United States
Craig
Hotel Hartness
Premium bedding, down duvets, pillow-top beds, in-room safe
Greenville Marriott

Greenville Marriott

4.0 star property
Greenville
8.6 out of 10, Excellent, (606)
"we enjoyed the bar"
United States
Elizabeth
The price is €100
includes taxes & fees
7 Dec - 8 Dec
Greenville Marriott
Two Bedroom Suite
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (768)
"Excellent stay as always! "
United States
Elena
The price is €105
includes taxes & fees
14 Dec - 15 Dec
Mint House Greenville - Downtown
Meeting facility
The Abernathy of Clemson

The Abernathy of Clemson

4.0 star property
Clemson
9.6 out of 10, Exceptional, (553)
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Apartment, 2 Bedrooms | Living area
Park Place Apartments by Landing

Park Place Apartments by Landing

4.0 star property
Greenville
7.6 out of 10, Good, (41)
"Great place for a different experience Enjoyed the train "
United States
Edward
Park Place Apartments by Landing
Trailside Wedge Cottage | Terrace/patio
The Station by Compo Hotels

The Station by Compo Hotels

4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (14)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is €279
includes taxes & fees
30 Nov - 1 Dec
The Station by Compo Hotels
Bar (on property)
Hotel Domestique

Hotel Domestique

4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is €391
includes taxes & fees
25 Nov - 26 Nov
Hotel Domestique
Restaurant
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4.0 star property
Pendleton
10.0 out of 10, Exceptional, (76)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is €165
includes taxes & fees
25 Nov - 26 Nov
Liberty Hall Bed and Breakfast
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
The view from Caesars Head after a storm
Photo by Michelle Hendrix
Open Photo by Michelle Hendrix

Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"Loved the location, attention to design details in all spaces, complimentary cocktails and delicious lunch in hotel restaurant. Really used the swamp rabbit trail right outside…"
marcy 2-night trip
Posted 20 hours ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from €100

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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