Are there any 5-star holiday rentals in Big Pine Key?

Although there aren't any 5-star holiday rentals in Big Pine Key on our site, we have a range of retreats that promise a fantastic getaway. Find one that suits your needs by searching our holiday rentals in Big Pine Key .

Big Pine Key which includes general coastal views, a bay or harbour and a coastal town

5 Star Hotels in Big Pine Key, Florida

Change your mind

Book hotels with free cancellation

Treat yourself

Be picky

Search almost a million properties worldwide

Check availability on Big Pine Key 5 Star Hotels

Tonight

Tomorrow

This weekend

Next weekend

Top Big Pine Key 5 Star Hotels

"Had a great stay"

includes taxes & fees

3 Aug - 4 Aug

Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon, FL

€297

29 Jul - 30 Jul

includes taxes & fees

8.8/10 Excellent! (1,004 reviews)

Still don't see what you're looking for?

See all properties in Big Pine Key.

You can also use these popular filters to refine your search.

Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key

Recent Reviews in Big Pine Key

5/5 Excellent

"Great midway location to relax and visit the FL Keys. The property is extremely clean, nice well maintained. The resort feels very secluded yet has easy access to Highway 1. Our room was large, comfortable, and clean with a nice furnished balcony facing the ocean. The food was excellent - it is on the pricey side so keep this in mind when you visit. They also have a large marketplace which offers less expensive food options and specialty coffees and beverages. There is a large family pool with menu service as well as three other smaller pools (plus a beach) if you prefer a more quiet location to swim and soak up the sun. We saw people in every age group including couples/familes/extended families. We loved the resort and highly recommend if you’re looking for a more upscale and pampered environment while visiting the Keys. "

A verified traveller stayed at Isla Bella Beach Resort & Spa

Posted 10 days ago

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Areas of Big Pine Key

Whispering Pines Hotels

Near an Attraction

Recommended cities for you

More top Big Pine Key Hotels

See a list of all hotels in Big Pine Key

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?

You'll find a variety of pricing options for 5-star hotels in Big Pine Key on Expedia. The amount you pay will depend on when you want to travel, trip length and other factors. Compare all of the available accommodation for your chosen dates and make use of our pricing and other filters to find the ideal high-end stay.

Search for the lowest price per night from €195

What makes a hotel 5 stars in Big Pine Key?

Flawless guest service chatacterises every 5-star hotel in Big Pine Key. From the moment you enter the lobby, staff attend to your every whim, whether recommending activities or providing a turn-down service. Also, hotels have to offer superior conveniences to obtain a 5-star rating. These can include luxury bath products, saunas or spas, swimming pools, gastronomic restaurants and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in Big Pine Key?

Use our handy filters to find an upscale retreat in Big Pine Key where most of what you need is included. Next, narrow your results for properties that have 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.

Members save 10% or more on over 100,000 hotels worldwide when you’re signed in