5 Star Hotels in Big Pine Key, Florida

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Big Pine Key 5 Star Hotels

Top Big Pine Key 5 Star Hotels

Our top choices for Big Pine Key 5-star hotels

Isla Bella Beach Resort & Spa
Property grounds

Isla Bella Beach Resort & Spa

5.0 star property
9.2 out of 10, Wonderful, (1039)
"Beautiful hotel with fantastic facilities and stunning views. Great spot for some family downtime - the kids loved the pools and the linked fishing charters were awesome "
The price is €276
includes taxes & fees
9 Sept - 10 Sept
Isla Bella Beach Resort & Spa
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

1996 Overseas Highway, Marathon, FL
The price is €181 per night from 2 Sept to 3 Sept
€181
2 Sept - 3 Sept
includes taxes & fees
8.8/10 Excellent! (1,287 reviews)
Still don't see what you're looking for?
See all properties in Big Pine Key.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Explore romantic Big Pine Key: its fishing, beaches, natural setting and more!

See all hotels in Big Pine Key
Big Pine Key which includes general coastal views, a bay or harbour and a coastal town

Top Big Pine Key Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?
You'll find a variety of pricing options for 5-star hotels in Big Pine Key on Expedia. The amount you pay will depend on when you want to travel, trip length and other factors. Compare all of the available accommodation for your chosen dates and make use of our pricing and other filters to find the ideal high-end stay.

  • Search for the lowest price per night from €181

What makes a hotel 5 stars in Big Pine Key?
Flawless guest service chatacterises every 5-star hotel in Big Pine Key. From the moment you enter the lobby, staff attend to your every whim, whether recommending activities or providing a turn-down service. Also, hotels have to offer superior conveniences to obtain a 5-star rating. These can include luxury bath products, saunas or spas, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Big Pine Key?
Use our handy filters to find an upscale retreat in Big Pine Key where most of what you need is included. Next, narrow your results for properties that have 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.