5 Star Hotels in Big Pine Key, Florida

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Check availability on Big Pine Key 5 Star Hotels

Top Big Pine Key 5 Star Hotels

Property grounds
Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
5.0 star property
9.2 out of 10, Wonderful, (1057)
"Extremely clean; nice surroundings; great pool choices; restaurant was good."
The price is €293
includes taxes & fees
19 Oct - 20 Oct
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon, FL
The price is €282 per night from 16 Oct to 17 Oct
€282
16 Oct - 17 Oct
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key
Big Pine Key which includes general coastal views, a bay or harbour and a coastal town

Top Big Pine Key Hotel Reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"Extremely clean; nice surroundings; great pool choices; restaurant was good."
Lana 3-night trip
Posted 10 days ago
Isla Bella Beach Resort & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?
You'll find a variety of pricing options for 5-star hotels in Big Pine Key on Expedia. The amount you pay will depend on when you want to travel, trip length and other factors. Compare all of the available accommodation for your chosen dates and make use of our pricing and other filters to find the ideal high-end stay.

  • Search for the lowest price per night from €190

What makes a hotel 5 stars in Big Pine Key?
Flawless guest service chatacterises every 5-star hotel in Big Pine Key. From the moment you enter the lobby, staff attend to your every whim, whether recommending activities or providing a turn-down service. Also, hotels have to offer superior conveniences to obtain a 5-star rating. These can include luxury bath products, saunas or spas, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Big Pine Key?
Use our handy filters to find an upscale retreat in Big Pine Key where most of what you need is included. Next, narrow your results for properties that have 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.

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