5 Star Hotels in Big Pine Key, Florida

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Check availability on Big Pine Key 5 Star Hotels

Next weekend
12 Jun - 14 Jun
In two weeks
19 Jun - 21 Jun

Our top choices for Big Pine Key 5-star hotels

On the beach, sun-loungers, beach umbrellas, beach towels

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,172 reviews)
"Beautiful hotel, grounds and wonderful staff."
United States
Anna
The price is €290
includes taxes & fees
7 Jul - 8 Jul
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

1996 Overseas Highway Marathon FL
The price is €183 per night from 7 Jul to 8 Jul
€183
7 Jul - 8 Jul
includes taxes & fees
8.6/10 Excellent! (1,161 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key

Top Big Pine Key Hotel Reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"First time staying at a resort in the Florida Keys. The whole experience was excellent giving May end sees less tourists and resort feels “private” to some extent. It’s definitely expensive given the resort fees and parking fees per night you pay for what you get. The restaurants/bars are Miami pricing and great food/drinks. Like there’s an adult only pool along with other pools. The rooms are very spacious (ours was on 3rd floor diagonal from the beach bar). We spent a whole day sitting on the beach chairs and relaxing by the bar watching the iguanas and dolphins. Would have appreciated if they provided water bottles in the room rather than us going to the water filling stations downstairs everytime to refill our bottles. There’s option to jet ski, take boat rides, etc but was too expensive for us. If you just want to enjoy some downtime away from Miami hustle/bustle sipping tropical drinks and relaxing in the pool, this resort is ideal. Just be ready to pay for the “views” and “vibes” at the resort, don’t expect getting extreme hospitality for the price though."
Mrityunjay 2-night trip
Posted 1 day ago
Isla Bella Beach Resort & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?
You'll find a variety of pricing options for 5-star hotels in Big Pine Key on Expedia. The amount you pay will depend on when you want to travel, trip length and other factors. Compare all of the available accommodation for your chosen dates and make use of our pricing and other filters to find the ideal high-end stay.

  • Search for the lowest price per night from €183

What makes a hotel 5 stars in Big Pine Key?
Flawless guest service chatacterises every 5-star hotel in Big Pine Key. From the moment you enter the lobby, staff attend to your every whim, whether recommending activities or providing a turn-down service. Also, hotels have to offer superior conveniences to obtain a 5-star rating. These can include luxury bath products, saunas or spas, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Big Pine Key?
Use our handy filters to find an upscale retreat in Big Pine Key where most of what you need is included. Next, narrow your results for properties that have 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.