St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

5 Star Hotels in Vatican City, Rome

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Check availability on Vatican City 5 Star Hotels

Tonight
7 Oct - 8 Oct
Tomorrow
8 Oct - 9 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Vatican City 5-star hotels

A modern gym with various exercise equipment, a large mirror, and a television.
Room
Room
Room

1. Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Rome City Centre
United States
Sharon
€624
includes taxes & fees
3 Nov - 4 Nov
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
A multi-story hotel with a grand entrance, multiple balconies, and a well-lit facade.
A rooftop lounge with modern seating, ambient lighting, and a city view.
A luxurious lobby with a central seating area, a bar, and a chandelier.
A rooftop bar with a glass ceiling, seating, and a bar stocked with bottles.

2. InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG
Rome City Centre
United States
Lauren
€530
includes taxes & fees
2 Nov - 3 Nov
InterContinental Rome Ambasciatori Palace by IHG
A hotel entrance with a covered entrance, a cobblestone pathway, and potted plants.
A grand lobby with a marble staircase, ornate chandeliers, and classical statues.
A silver sports car parked in front of a building with a sign reading "Gina Hotel Baglioni."
A family on a balcony overlooking a cityscape with historic buildings and a dome in the distance.

3. Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World
Rome City Centre
United States
Robert
€492
includes taxes & fees
2 Nov - 3 Nov
Baglioni Hotel Regina - The Leading Hotels of the World
A luxurious indoor pool area with a circular pool, large windows, and a view of the cityscape.
A modern interior with a bar area, seating arrangements, and large windows offering natural light and views.
A luxurious lobby with a grand ceiling, elegant furniture, and large windows.
A grand lobby with checkered flooring, ornate chandeliers, and classic furniture.

4. The Westin Excelsior, Rome

The Westin Excelsior, Rome
Rome City Centre
United States
bernie
€408
includes taxes & fees
2 Nov - 3 Nov
The Westin Excelsior, Rome
A hotel with ivy-covered walls, a prominent tower, and a well-lit entrance.
A hotel room with a large window, a red armchair, a table with a book, and a television on the wall.
A rooftop terrace with tables set for dining, palm trees, and a view of a large dome building in the background.
A modern hotel room with a large bed, a television, a small table with a plant, and a large tapestry on the wall.

5. Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux
Rome City Centre
United States
Franz
€413
includes taxes & fees
5 Nov - 6 Nov
Hotel Raphaël – Relais & Châteaux
A hotel entrance with a cobblestone pathway, large potted plants, and a sign indicating room number 36.
A modern lobby with a reception desk, seating area, and bar.
A modern interior with seating areas, decorative plants, and a red carpet.
A neatly made bed with white linens, two glasses of white wine, and a tray with fruit and a small bottle on a wooden tray.

6. Umiltà 36 - Preferred Hotels & Resorts

Umiltà 36 - Preferred Hotels & Resorts
Rome City Centre
Canada
Ghassan
€733
includes taxes & fees
5 Nov - 6 Nov
Umiltà 36 - Preferred Hotels & Resorts
A rooftop terrace with a table set for dining, featuring a lamp, wine glass, and plates of food. In the background, there is a large classical building with statues on top.
A modern lobby with a sofa, chairs, a coffee table, and potted plants.
A modern hotel room with a view of a historic building, a dining area with a table and chairs, and potted plants.
A hotel room with a bed, a chair, a small table, and a view of a cityscape through a large window.

7. Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
Rome City Centre
United States
Thomas
€369
includes taxes & fees
1 Nov - 2 Nov
Radisson Collection Hotel, Roma Antica
A luxurious dining area with ornate chandeliers, elegant table settings, and a scenic view of the cityscape at dusk.
A grand staircase with black steps and gold accents, leading to a high-ceilinged room with a chandelier.
A hotel entrance with flags, a well-lit facade, and a street view.
A grand lobby with marble columns, a central seating area, and a decorative mirror.

8. Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World
Rome City Centre
Canada
Janelle
€516
includes taxes & fees
5 Nov - 6 Nov
Hotel Splendide Royal - The Leading Hotels of the World
The entrance of Grand Hotel Palace with a grand arched doorway, a chandelier, and a potted plant.
A grand hotel entrance with a large archway, a flag, and outdoor seating with umbrellas.
A luxurious room with a bar area, red chairs, a large chandelier, and a painting on the wall.
A historic building with a grand entrance, multiple balconies, and outdoor seating areas.

9. Grand Hotel Palace Rome

Grand Hotel Palace Rome
Rome City Centre
United States
Babak
€403
includes taxes & fees
7 Nov - 8 Nov
Grand Hotel Palace Rome
A spacious lobby with a reflective floor, a central seating area, and a decorative wall with a floral pattern.
A modern hotel room with a sofa, armchair, and a glass coffee table. There is a flat-screen TV mounted on the wall and a lamp on a side table.
The exterior of Nobu Hotel Via Veneto with a classic architectural style, featuring a marquee sign, arched entrances, and potted plants at the doors.
A bar area with shelves of liquor bottles and a curved wall design.

10. Nobu Hotel Roma

Nobu Hotel Roma
Rome City Centre
United States
LARRY
€555
includes taxes & fees
2 Nov - 3 Nov
Nobu Hotel Roma
A grand hotel lobby with a large chandelier, seating areas, and a checkered floor pattern.
A grand banquet hall with multiple round tables, ornate chandeliers, and a ceiling fresco.
View from property
A grand hall with a large black grand piano, ornate chandeliers, and a ceiling with a detailed fresco.

11. The St. Regis Rome

The St. Regis Rome
Rome City Centre
United States
John
€1,049
includes taxes & fees
18 Oct - 19 Oct
The St. Regis Rome
An outdoor terrace with tables and chairs, a large umbrella, and a city view at sunset.
A restaurant interior with multiple dining tables, chairs, and a bar area.
A hotel room with two beds, a large painting on the wall, a modern lamp, and a view of the city through the window.
A hotel room with two beds, a large window with a view of buildings, a desk with a lamp, and a small window on the right.

12. U-Visionary Roma Hotel

U-Visionary Roma Hotel
Rome City Centre
United Kingdom
Nisha
€366
includes taxes & fees
1 Nov - 2 Nov
U-Visionary Roma Hotel
A balcony with outdoor furniture, a table with glasses, and a book.
A hotel room with a large bed, a vanity with a mirror, a chandelier, and a view of the bathroom.
A historic building with a classic facade, multiple balconies, and flags.
A modern bathroom with a bathtub, a shower area, and a vanity with a mirror.

13. Hotel d'Inghilterra Roma - Starhotels Collezione

Hotel d'Inghilterra Roma - Starhotels Collezione
Rome City Centre
United States
Renee
€740
includes taxes & fees
2 Nov - 3 Nov
Hotel d'Inghilterra Roma - Starhotels Collezione
An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.
A modern interior with a glass railing and a marble floor.
A spacious lobby with a marble floor, glass elevator, and a view of the cityscape through large windows.
A large hotel with multiple floors, a well-maintained lawn, and outdoor seating areas.

14. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
Rome City Centre
Mexico
LEONARDO
€481
includes taxes & fees
6 Nov - 7 Nov
NH Collection Roma Palazzo Cinquecento
A grand hall with a long table set for a banquet, ornate chandeliers, and classical wall paintings.
A grand staircase with a statue at the top, flanked by ornate balustrades and a chandelier.
A room with a central seating area, framed pictures on the walls, and busts on the right.
A bartender preparing a cocktail with a glass and a spoon.

15. Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World
Rome City Centre
Canada
Anais
€619
includes taxes & fees
6 Nov - 7 Nov
Palazzo Roma - The Leading Hotels of the World
A dining table set with plates, glasses, and a vase of flowers on a balcony with red chairs, overlooking a historic building with statues.
A building entrance with a sign reading 'NH COLLECTION FOR IMPERIAL,' potted plants on either side, and a staircase leading inside.
A hotel dining area with marble walls, red chairs, and tables set for dining.
A hotel room with a large bed, a TV, a desk with a chair, and large windows with city views.

16. NH Collection Roma Fori Imperiali

NH Collection Roma Fori Imperiali
Rome City Centre
United States
Shawn
€614
includes taxes & fees
5 Nov - 6 Nov
NH Collection Roma Fori Imperiali
A spacious lobby with a patterned carpet, columns, and potted plants.
A bar area with a statue, bar stools, and a patterned floor.
A dining area with a round table, two chairs, and a view of buildings through a window with curtains.
A traditional room with a high ceiling, wooden lattice partitions, a green sofa, a small table, and a bench.

17. Orient Express La Minerva

Orient Express La Minerva
Rome City Centre
France
Brahim
€1,252
includes taxes & fees
1 Nov - 2 Nov
Orient Express La Minerva
An outdoor seating area with a round table and chairs, surrounded by potted plants.
A spacious lobby with multiple seating areas, large potted plants, and a central bar area.
A grand marble staircase with multiple landings and ornate railings.
A modern bar area with a marble countertop, multiple bar stools, and a variety of potted plants.

18. Six Senses Rome

Six Senses Rome
Rome City Centre
United States
Kurt
€1,095
includes taxes & fees
1 Nov - 2 Nov
Six Senses Rome
A grand entrance with a glass door, a balcony with ornate railings, and a number '26' on the wall.
A luxurious bar area with marble flooring, gold bar counters, and a seating area with a blue sofa and round ottomans.
A spacious lobby with modern furniture, a large abstract painting, and a unique chandelier.
A narrow street with buildings on either side, featuring balconies and windows with shutters.

19. W Rome

W Rome
Rome City Centre
United States
Katherine
€500
includes taxes & fees
6 Nov - 7 Nov
W Rome
A building facade with a central entrance, flanked by two windows with curtains, and a balcony with greenery.
A bar area with wooden chairs and sofas, a wall of illuminated liquor bottles, and greenery overhead.
A rooftop pool area with lounge chairs, potted plants, and a view of surrounding buildings.
An outdoor seating area with tables and chairs, surrounded by large potted plants and a building with balconies in the background.

20. The Rome EDITION

The Rome EDITION
Rome City Centre
United Kingdom
Miss Vishali
€711
includes taxes & fees
3 Nov - 4 Nov
The Rome EDITION
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Vatican City.
Hotel Delle Nazioni

Hotel Delle Nazioni

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€215
4 Nov - 5 Nov
includes taxes & fees
9.2/10 Wonderful! (1,012 reviews)
Hotel Delle Nazioni
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

Via Cavour 15 Rome RM
€196
18 Oct - 19 Oct
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
Bettoja Hotel Mediterraneo
Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden

Via Flavia 106 Rome RM
€243
5 Nov - 6 Nov
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
Marcella Royal Hotel - Rooftop Garden
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Vatican City

Marvel at Michelangelo's masterpiece ceiling in the Sistine Chapel before climbing St. Peter's Basilica dome for panoramic views. Reserve tickets for the Vatican Museums well in advance to explore one of the world's greatest art collections without the longest lines.

See all hotels in Vatican City
St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

Top Vatican City Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Vatican City?
Get ready for 5-star pampering at Villa Agrippina Gran Meliá - The Leading Hotels of the World, Hotel Indigo Rome - St. George, an IHG Hotel or DOM Hotel. These are some of the leading properties in Vatican City based on Expedia traveller reviews. Choose your favourite and get a taste of the good life!
How much does it cost to stay in a 5-star hotel in Vatican City?
There are a range of pricing options for a 5-star hotel in Vatican City on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare all of the available properties for your preferred dates and use our pricing and other filters to land the ideal upscale stay.
  • Search for the lowest price per night from €196
What makes a hotel 5 stars in Vatican City?
In Vatican City, a hotel needs to offer a specific level of upscale amenities to be designated 5 stars. These can include on-site gyms, gourmet restaurants, saunas and spas, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary service. You'll enjoy things like in-room massages, concierge services and nightly turn-down services. Some may even offer extra touches like a welcome gift.

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