Barrio de Santiago Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €185 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Barrio de Santiago
Merida Cathedral which includes heritage architecture and night scenes

Mérida Centro

3 out of top 10 points of interest in this area
4/5(32 area reviews)

The core of the White City is a fusion of Mayan ruins, Spanish colonial churches and intriguing galleries and museums.

Find hotels in Mérida Centro

Top hotels in Barrio de Santiago

Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
Fully refundableReserve now, pay when you stay
The price is €227 per night from 20 Mar to 21 Mar
€227
20 Mar - 21 Mar
includes taxes & fees
9.8/10 Exceptional! (106 reviews)
Wonderful rooms and staff members were incredible!

Reviewed on 25 Feb 2026

Casa Loreto 1893
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (343 reviews)
A perfect place to stay in Merida! Comfortable, quiet, excellent breakfast, relaxing pool, very nice rooms, and great people. Close but not TOO close to activities.

Reviewed on 3 Mar 2026

Get rates
Hotel Unknown
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
Fully refundableReserve now, pay when you stay
The price is €43 per night from 10 Mar to 11 Mar
€43
10 Mar - 11 Mar
includes taxes & fees
7.8/10 Good! (1,002 reviews)
the room was clean and the bed comfortable. The shower was very weak and it didn't always have hot water.

Reviewed on 4 Feb 2026

Hotel Ambassador Merida
See all 1,258 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Barrio de Santiago holiday package cost?
Get your credit card ready, because a trip to Barrio de Santiago starts from an affordable . When you bundle your flights, hotels and car rentals into a holiday package, you'll score the biggest bargains.
How do I get a cheap travel package to Barrio de Santiago?
Just imagine all the fun things you could do in Barrio de Santiago with a pile of extra cash in your pocket. Watch your savings stack up when you combine your flights, hotels and other bookings into a Barrio de Santiago holiday package. You have loads of choice when you book with Expedia too. In fact, you can choose from more than 550 airlines and 1,000,000 hotels globally. Whether you're taking a holiday with the family or going it alone, organising a trip to Barrio de Santiago is better with a package.
Where should I stay in Barrio de Santiago?
With loads to explore in Barrio de Santiago, we recommend you book a room in a hotel near its attractions. Mérida Cathedral, U.S. Consulate Merida and Yucatan International Convention Centre are some top ones to add to your itinerary.
What are the top hotels in Barrio de Santiago?
Book a stay at Hotel Unknown. It's one of this area's most in-demand hotels. Another highly rated option in Barrio de Santiago is Hostal Casa Nico - Hostel.
How far in advance should I book my Barrio de Santiago holiday?
Reserving your spot early with Expedia means one less thing to worry about. A number of air carriers display prices up to 12 months prior to take off. This is often the cheapest time to book. If circumstances have left you booking late, great deals to Barrio de Santiago occasionally appear in the weeks leading up to departure.
What does an Expedia Barrio de Santiago travel package include?
With Expedia, you can choose any combination of hotels, flights and car rentals to build your perfect Barrio de Santiago travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Barrio de Santiago travel package?
A package can be easier on the credit card than separately booking everything you need for your adventure. For example, bundle your flights, hotels and rental cars and score impressive savings. No matter your holiday plans, you'll find a package that suits your budget.
Can I choose my airline with a Barrio de Santiago Expedia holiday package?
You can, and with over 550 airlines to select from globally, you're spoiled for choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Barrio de Santiago holiday package?
Yes, it's possible to cancel your Barrio de Santiago booking if your plans have changed. Whether you'll incur a penalty or not depends on your airline, hotel or car rental company. You may be able to cancel or change your booking for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Things to do

Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

€9
per adult
80% of travellers recommend
Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes
Mérida: La Quinta Montes Molina Museum Entrance

Mérida: La Quinta Montes Molina Museum Entrance

€7
per adult
Mérida: La Quinta Montes Molina Museum Entrance
Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida

Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida

€98
per adult
90% of travellers recommend
Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida
See all activities in Mérida
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.