Byron Hotels

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Tonight
21 Dec - 22 Dec
Tomorrow
22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

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Our top choices for Byron hotels

Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1010)
"We had a wonderful stay!"
United States
Sarah
The price is €81
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Rochester-South
Lobby
Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very good, (432)
"Breakfast was fresh and plentiful. The service was amazing. We always stay here when we come to Spring Valley to meet family. We really enjoy this hotel. We had three rooms this time and they were great"
United States
Carol
The price is €80
includes taxes & fees
19 Jan - 20 Jan 2026
Americas Best Value Inn & Suites Spring Valley
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1004)
"Clean rooms, very friendly staff and just all around homey "
United States
Kathy
The price is €72
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1025)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is €69
includes taxes & fees
24 Dec - 25 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (892)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is €79
includes taxes & fees
25 Dec - 26 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Indoor pool, open 7:00 AM to 11:00 PM, pool loungers
AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
Rochester
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
The price is €74
includes taxes & fees
25 Dec - 26 Dec
AmericInn by Wyndham Rochester
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1146)
"Good price, room clean, descent breakfast. I have stayed here several time"
United States
Amy M
The price is €72
includes taxes & fees
26 Dec - 27 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (326)
"Great place"
United States
Abidemi
The price is €69
includes taxes & fees
28 Dec - 29 Dec
Spark by Hilton Rochester South
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (1005)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is €127
includes taxes & fees
23 Dec - 24 Dec
Hyatt House Rochester/Mayo Clinic Area
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (853)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is €105
includes taxes & fees
27 Dec - 28 Dec
Hilton Garden Inn Rochester Downtown, MN
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1003)
"Pool was nice "
Canada
Jesse
The price is €88
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn & Suites Rochester-North
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (770)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is €83
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (963)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is €109
includes taxes & fees
26 Dec - 27 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (546)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is €169
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Rochester Mayo Clinic Area
Front of property – evening/night
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very good, (1837)
"It was just perfect!"
United States
Shannon
The price is €132
includes taxes & fees
24 Dec - 25 Dec
Kahler Grand Hotel
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very good, (792)
"Great place to stay. Freindly staff"
United States
joel
The price is €88
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.6 out of 10, Excellent, (764)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is €86
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Room, 2 Queen Beds
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very good, (1522)
"Clean room, good room service and good breakfast."
United States
Donald
The price is €125
includes taxes & fees
29 Dec - 30 Dec
Kahler Inn and Suites - Mayo Clinic Area
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
9.6 out of 10, Exceptional, (481)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is €125
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Reception
America's Stay Inn Stewartville

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very good, (419)
"Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean."
Canada
Robert
America's Stay Inn Stewartville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Byron attractions

Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.
See properties

High Point Shopping Center

You can do some window-shopping at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene.
See properties

Top Byron Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"Rooms have had the large items renovated(carpets, bathroom) but the small details are not t"
Lana 4-night trip
Posted 1 day ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

More cheap stays in Byron

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

4210 Highway 52 North Rochester MN
The price is €64 per night from 24 Dec to 25 Dec
€64
24 Dec - 25 Dec
includes taxes & fees
7.8/10 Good! (1,004 reviews)

Frequently asked questions

Where is the best place to stay in Byron?
Located 9 mi (14.4 km) from the heart of Byron, Kahler Grand Hotel is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Byron.
What are some of the best holiday rentals that Byron has to offer?
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester: This holiday home rental outside of Byron has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop and a microwave. See all vacation rentals in Byron.
If I need to cancel my hotel reservation in Byron, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.
How is it to stay in Byron?
Visitors can enjoy all that Byron has to offer, including the zoo, golf courses and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 2 hotels and other accommodation options to choose from. Find out more about Byron.
What should I see while I'm in Byron?
Favourite places to visit include High Point Shopping Center, Putting Green and Links of Byron Mini Golf. A couple of additional sights to add to your itinerary are Cheery Meadows Center and Byron Town Square. Take a look at what more there is to see and do in Expedia's Byron guide.
What's the seasonal weather in Byron?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

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