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Byron Hotels

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Check prices for these dates

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Byron hotels

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.
A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.
A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

1. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
Rochester
United States
yuan
€85
includes taxes & fees
15 Oct - 16 Oct
Comfort Inn & Suites West - Medical Center
An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.
A hotel room with a kitchen area, a bed, a TV, and a seating area.
A modern kitchen with granite countertops, a built-in microwave, and a sink. There are two wooden chairs and a small table.
A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.

2. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
€99
includes taxes & fees
1 Oct - 2 Oct
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
A modern dining area with high tables, chairs, and pendant lighting.
A hotel room with two beds, a desk with a computer, a chair, and a window with a view.
A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.
A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

3. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
United States
Dr. Tim
€103
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Rochester-North
A spacious lobby with a reception desk, sofas, and a coffee table.
A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.
A hotel room with a large bed, a sofa, a TV, and a desk.
An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.

4. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
Rochester
United States
Jacqueline
€90
includes taxes & fees
18 Oct - 19 Oct
Sleep Inn & Suites West-Near Medical Center
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.
A compact hotel room with a kitchenette, a dining area, a sofa, and a bed.
A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

5. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Rochester
United States
Whitney
€70
includes taxes & fees
5 Oct - 6 Oct
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
A hotel reception desk with a wooden counter, a computer, and a vase with flowers.
An indoor swimming pool with wooden beams and white chairs around it.
A hotel room with a large bed, a separate bathroom with a bathtub, and a skylight ceiling.
A hotel room with a large bed, a view through a sliding glass door to an outdoor area, a nightstand with a lamp, and a wooden headboard.

6. Baymont by Wyndham Kasson Rochester Area

Baymont by Wyndham Kasson Rochester Area
Kasson
United States
Lynnette
€60
includes taxes & fees
30 Sept - 1 Oct
Baymont by Wyndham Kasson Rochester Area
A restaurant with a staircase, dining tables, chairs, a coffee machine, and a refrigerator.
A spacious lobby with a high ceiling, a central seating area with patterned sofas and ottomans, a reception desk, and a staircase leading to an upper level.
An indoor swimming pool with a wooden ceiling and large windows.

7. Quality Inn near Medical Center

Quality Inn near Medical Center
Rochester
United States
Lerry
€63
includes taxes & fees
14 Oct - 15 Oct
Quality Inn near Medical Center
An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.
A hotel room with two beds, a desk, a chair, a television, and a window with curtains.
A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.
A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

8. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park
€72
includes taxes & fees
26 Sept - 27 Sept
Med City Inn & Suites - Mayo Clinic Area
An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.
A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.
A hotel reception area with a red 'Hello' sign, a reception desk, a coffee station, and a fireplace.
A hotel reception area with a coffee station, seating area, and a fireplace.

9. TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester
Rochester
United States
Terry
€98
includes taxes & fees
2 Oct - 3 Oct
TownePlace Suites by Marriott Rochester
A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.
A hotel room with two beds, a desk, a chair, a television, and a kitchenette.
A hotel dining area with multiple tables and chairs, a coffee station, and a seating area with sofas.
A reception desk with a wooden finish, a blue wall with the Holiday Inn Express logo, and a welcome sign for members.

10. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
United States
Janet
€111
includes taxes & fees
2 Oct - 3 Oct
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.
An indoor swimming pool with a slide, seating area, and a large frog statue.
A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.
A hotel room with two beds, a desk, a chair, and a mirror.

11. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
United States
Warren
€81
includes taxes & fees
27 Sept - 28 Sept
AmericInn by Wyndham Rochester Near Mayo Clinic
A modern hotel lobby with a reception desk, seating area, and a kitchenette.
A hotel room with a large bed, a desk, a chair, and a kitchenette.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A small, well-organized pantry with shelves stocked with snacks and beverages.

12. Spark by Hilton Rochester South

Spark by Hilton Rochester South
Rochester
United States
Kimberly
€90
includes taxes & fees
5 Oct - 6 Oct
Spark by Hilton Rochester South
A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.
A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.
A pool area with a table and chairs, a lifeguard chair, and a pool lift.
A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

13. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
dennis
€106
includes taxes & fees
30 Sept - 1 Oct
Hampton Inn Rochester-South
A hotel reception area with a black reception desk, a 'WELCOME' sign, a bench, and two armchairs.
A multi-story hotel with a brick facade, a covered lobby entrance, and a parking lot with several cars.
A compact kitchen with white cabinets, a microwave, a refrigerator, a sink, and a chair.

14. Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North
Rochester
Canada
Mohamud
€64
includes taxes & fees
24 Sept - 25 Sept
Extended Stay America Suites Rochester North
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A compact hotel room with a kitchenette, a bed, a TV, and a seating area.
A compact hotel room with a kitchenette, a dining area, a seating area with a sofa and armchairs, and a large window with curtains.
An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

15. Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG
Rochester
United States
MATTHEW
€132
includes taxes & fees
24 Oct - 25 Oct
Staybridge Suites Rochester - Commerce Dr NW by IHG
A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.
A compact laundry area with a washing machine, dryer, and a water fountain.
A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.
A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

16. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
Ashley
€75
includes taxes & fees
4 Oct - 5 Oct
Econo Lodge Mayo Clinic Area
A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.
A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.
A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.
A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

17. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Rochester
€76
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.
A gym with treadmills, elliptical machines, and a stationary bike.
A conference room with round tables and chairs, white walls, and a carpeted floor.
A reception desk with a wooden finish, a large illuminated 'C' sign, and a modern light fixture on the ceiling.

18. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
JOSEPH
€83
includes taxes & fees
22 Oct - 23 Oct
Comfort Inn & Suites Rochester South Mayo Clinic
An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.
A modern hotel room with a bed, desk, and kitchenette.
A modern lounge area with a sofa, chairs, and tables.
A modern restaurant with a counter, seating area, and a TV screen.

19. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
Rochester
United States
Vickie
€123
includes taxes & fees
3 Oct - 4 Oct
Home2 Suites by Hilton Rochester Mayo Clinic Area
An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.
A garden with a water feature, rocks, and yellow umbrellas.
A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.
A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
United States
Carrie
€108
includes taxes & fees
5 Oct - 6 Oct
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
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Stay near popular Byron attractions

Oxbow Park

8.8/10 (5 reviews)
Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.
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Community Center Park

Community Center Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.
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Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.
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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.
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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.
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High Point Shopping Center

You can do some window-shopping at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene.
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Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.
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Salem Town Hall

After visiting Salem Town Hall, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.
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Top Byron Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"Staff very good"
Jim 1-night trip
Posted 11 hours ago
Med City Inn & Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"We enjoyed our stay. The breakfast was wonderful. We were disappointed the hot tub only ran for the first evening though and was down for maintenance after. And the exercise room was a bit grimy"
Larry 1-night trip
Posted 16 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"Enjoyed my stay Will return"
Harmik 2-night trip
Posted 16 hours ago
Hyatt House Rochester/Mayo Clinic Area
Brentwood Inn & Suites

Brentwood Inn & Suites

8/10 Good
"Easy shuttle service to Mayo Clinic."
Susan 1-night trip
Posted 17 hours ago
Brentwood Inn & Suites
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Clean room and hotel. Breakfast was great"
JOANN 2-night trip
Posted 2 days ago
Hampton Inn Rochester-South
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Very nice hotel and well maintained!"
Nick 1-night trip
Posted 2 days ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent
"The hotel was clean and quiet. We were happy also to have a shuttle to the Mayo Clinic"
Rita 1-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent
"Was there for a surgery at the Mayo and they were so helpful and accommodating. Very grateful for the facility and the staff"
Kristi 6-night trip
Posted 3 days ago
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Aspen Select

Aspen Select

10/10 Excellent
"Room was very clean"
Jeffery 3-night trip
Posted 4 days ago
Aspen Select

More cheap stays in Byron

Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN
€58
4 Oct - 5 Oct
includes taxes & fees
Birch Hill Suite Rochester – Med City
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
€72
26 Sept - 27 Sept
includes taxes & fees
7.8/10 Good! (1,024 reviews)
Med City Inn & Suites - Mayo Clinic Area
Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN
€83
22 Oct - 23 Oct
includes taxes & fees
Comfort Inn & Suites Rochester South Mayo Clinic
Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
€94
26 Sept - 27 Sept
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)
Brentwood Inn & Suites
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN
€97
18 Oct - 19 Oct
includes taxes & fees
Holiday Inn Express Rochester South - Mayo Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN
€99
1 Oct - 2 Oct
includes taxes & fees
8.2/10 Very good! (1,008 reviews)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Frequently asked questions

Where is the best place to stay in Byron?
Located 9.3 mi (14.9 km) from the heart of Byron, AmericInn by Wyndham Rochester Near Mayo Clinic is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Byron.
What are some of the best holiday rentals that Byron has to offer?
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: This holiday home rental outside of Byron offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Byron.
If I need to cancel my hotel reservation in Byron, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.
How is it to stay in Byron?
Visitors can enjoy all that Byron has to offer, including the zoo, golf courses and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 3 hotels and other accommodation options to choose from. Find out more about Byron.
What should I see while I'm in Byron?
Favourite places to visit include Oxbow Park, Links of Byron Mini Golf and Cheery Meadows Center. A couple of additional sights to add to your itinerary are High Point Shopping Center and Byron Town Square. Take a look at what more there is to see and do in Expedia's Byron guide.
What's the seasonal weather in Byron?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

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