St. Charles Hotels from €59 - Fully Refundable Options

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Our top choices for St. Charles hotels

A hotel room with two beds, a large landscape painting above the headboard, a bedside table with a phone, and a blue patterned rug.

A modern room with two sofas, a coffee table, and large windows with curtains.

A reception area with a counter, a clock, a desk with a computer, and a framed picture on the wall.

A gym with treadmills, an elliptical, and a stationary bike.

1. Days Inn by Wyndham Winona

Winona

Kimberly

€70

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large mirror.

A hotel room with a sofa, a small table, a TV, a microwave, and a door.

A multi-story hotel with a prominent "American" sign, a parking lot with several cars, and a landscaped entrance area.

A hotel lobby with seating, a fireplace, a clock, and a reception area.

2. AmericInn by Wyndham Winona

Winona

SANDRA

€116

includes taxes & fees

11 Oct - 12 Oct

A cozy living room with a fireplace, a sofa, a coffee table, and a view through large windows.

A white two-story house with green shutters, a porch, and a sign that reads "Bed & Breakfast."

A dining room with a long wooden table set for a meal, surrounded by chairs.

A bedroom with a bed, a nightstand, a lamp, and a chandelier.

3. Carriage House B&B

Historic Downtown Winona

Mark

€118

includes taxes & fees

28 Sept - 29 Sept

A table set for a meal with various dishes, glasses of orange juice, and a vase with flowers.

A room with a portrait framed in gold, red curtains, and a table with ornate candle holders.

A spacious room with wooden paneling, a chandelier, a fireplace, and a large rug.

A grand staircase with a floral carpet, wooden balustrades, and a chandelier.

4. Alexander Mansion Bed and Breakfast

Historic Downtown Winona

Charlene

€105

includes taxes & fees

29 Sept - 30 Sept

A hotel room with two beds, a desk with a chair, a TV, and a large waterfall painting on the wall.

A hotel room with large windows, a clock, and framed pictures on the walls.

A reception area with a modern design, featuring a check-in counter, a door, and a small seating area with red stools.

An outdoor patio with a table and chairs, a red umbrella, and a view of trees and a sunset.

5. Super 8 by Wyndham Winona MN

Winona

William

€63

includes taxes & fees

1 Oct - 2 Oct

A modern hotel lobby with a dining area, seating arrangements, and a stone fireplace.

An outdoor patio area with stone walls, a stone fireplace, and multiple tables and chairs.

A hotel with a modern design, featuring a stone facade and a covered entrance.

An indoor swimming pool with clear glass walls, a tiled floor, and a few chairs around the pool area.

6. Fairfield Inn & Suites by Marriott Winona

Winona

Mary

€140

includes taxes & fees

1 Oct - 2 Oct

A two-story house with a porch and a covered entryway.

A bedroom with a wooden wardrobe, a bedside table with a lamp, and a bed with white bedding and a red pillow.

A porch with a white door labeled "WENNESON" and a welcome wreath.

A room with two patterned sofas, a small table with a lamp, and a window with curtains.

7. The Wen Inn formerly Andor Wenneson

Peterson

Naomi

€133

includes taxes & fees

21 Oct - 22 Oct

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A spacious living area with a high ceiling, wooden beams, a blue armchair, a sofa, and a glass coffee table.

A rustic bar area with wooden beams, a wooden counter, and sacks of grain.

A cozy living room with a fireplace, a staircase, and a dining area.

8. Stone Mill Hotel & Suites

Lanesboro

Jenifer

€99

includes taxes & fees

18 Oct - 19 Oct

A hotel pool area with multiple lounge chairs, a pool, and a second-floor balcony with windows.

A hotel room with a large bed, a separate bathroom with a bathtub, and a small bedside table with a lamp.

A brick building with a sign reading "Riverport Inn & Suites" and two flags.

A spacious lobby with a stone fireplace, leather seating, a staircase with glass railings, and a view of the outside through large windows.

9. Express Suites Riverport Inn & Suites

Winona

Sasha

€118

includes taxes & fees

4 Oct - 5 Oct

A multi-story building with a balcony, surrounded by various potted plants and flowers.

An outdoor patio with tables and chairs, green umbrellas, and a wooden deck.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

A bedroom with a four-poster bed, a sitting area with a sofa, a small table with a vase, and a bathtub.

10. Green Gables Inn

Lanesboro

Sandra

€79

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with brick walls, green railings, and hanging flower baskets.

A spacious living area with leather sofas, a coffee table with magazines, and a stone fireplace.

A pool with a large, colorful fish-shaped slide.

A hotel with a central clock tower, multiple windows, and a parking lot with cars.

11. The Plaza Hotel & Suites Winona

Winona

Christopher

€162

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a blue sofa, a wooden coffee table, a lamp, a TV, and a door leading to a balcony.

A hotel indoor pool with clear water, lounge chairs, and a seating area with an umbrella.

12. Holiday Inn Express & Suites Winona by IHG

Winona

Kristie

€140

includes taxes & fees

25 Oct - 26 Oct

A display of ceramic mugs and bowls on a table with a white tablecloth, illuminated by string lights.

A kitchen with wooden cabinets, a granite countertop, and a built-in microwave.

A spacious room with a high ceiling, wooden beams, and a large window displaying a sign for The Rushford Inn.

13. The Rushford Inn

Rushford

sonja

€135

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, and a lamp.

A lobby with a checkered floor, two blue armchairs, a table with a lamp, and a 'WELCOME' sign.

A living room with a brick fireplace, two armchairs with decorative pillows, and a framed map on the wall.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

14. Country Trails Inn & Suites

Preston

Jeannie

€123

includes taxes & fees

28 Sept - 29 Sept

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A small, well-organized pantry with shelves stocked with snacks and beverages.

15. Spark by Hilton Rochester South

Rochester

Kimberly

€82

includes taxes & fees

3 Oct - 4 Oct

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A bar with wooden stools and a neon sign.

A hotel room with two beds, a desk, a chair, and a mirror.

16. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Jeanne

€82

includes taxes & fees

30 Sept - 1 Oct

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.

A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

17. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Kathryn

€76

includes taxes & fees

4 Oct - 5 Oct

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

18. Econo Lodge Mayo Clinic Area

Rochester

Ashley

€74

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A gym with treadmills, elliptical machines, and a stationary bike.

A kitchen with a waffle maker, a waffle iron, and a waffle maker instruction manual.

A snack bar with a variety of packaged snacks, a refrigerator stocked with beverages, and a microwave.

19. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Darlene

€78

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.

A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

A hotel room with two beds, a desk, a chair, a television, and a window with curtains.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

20. Med City Inn & Suites - Mayo Clinic Area

Kutzky Park

Rick

€72

includes taxes & fees

28 Sept - 29 Sept

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Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles

Top St. Charles Hotel Reviews

Kahler Grand Hotel

10/10 Excellent

"Staff very helpful. Essex restaurant very good. Rooms small. Overall good."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"Great place to stay— clean, quiet, helpful staff and good breakfast. Comfortable and clean rooms."

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Na"

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"The hotel is clean, comfortable, and offers easy parking. Mayo Clinic is within walking distance (half mile). The staff is helpful and friendly. Bonus: the pool and hot tub area is very relaxing!"

Express Suites Riverport Inn & Suites

8/10 Good

"The room was clean and the staff was super friendly! Nice variety to choose from in the breakfast! It was a very good experience and I would stay there again!"

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent

"Very nice place! I would definitely stay there again."

Holiday Inn Express Rochester South - Mayo Area by IHG

10/10 Excellent

"Room was very clean, staff was amazing. Hot tub not working."

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"We had a great night of sleep after a long day at Mayo. The bed was comfortable. Hotel was clean and staff was helpful and very friendly. The breakfast was good with many options."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"Staff at check in,close to mayo"

More cheap stays in St. Charles

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN

€59

4 Oct - 5 Oct

includes taxes & fees

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

€63

1 Oct - 2 Oct

includes taxes & fees

7.6/10 Good! (1,006 reviews)

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

€72

28 Sept - 29 Sept

includes taxes & fees

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN

€78

25 Oct - 26 Oct

includes taxes & fees

8.8/10 Excellent! (1,008 reviews)

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

€95

1 Oct - 2 Oct

includes taxes & fees

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN

€97

18 Oct - 19 Oct

includes taxes & fees

8.8/10 Excellent! (1,002 reviews)

Frequently asked questions

Where is the best place to stay in St. Charles?

AmericInn by Wyndham Rochester Near Mayo Clinic, located 20.5 mi (32.9 km) from the heart of St. Charles, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.

What are some of the best holiday rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: This holiday home rental outside of St. Charles offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

What's it like to stay in St. Charles?

Visitors can enjoy all that St. Charles has to offer, including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodation options to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

A couple of favourite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.

What's the weather like in St. Charles?

The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

St. Charles Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St. Charles

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Charles hotels

1. Days Inn by Wyndham Winona

2. AmericInn by Wyndham Winona

3. Carriage House B&B

4. Alexander Mansion Bed and Breakfast

5. Super 8 by Wyndham Winona MN

6. Fairfield Inn & Suites by Marriott Winona

7. The Wen Inn formerly Andor Wenneson

8. Stone Mill Hotel & Suites

9. Express Suites Riverport Inn & Suites

10. Green Gables Inn

11. The Plaza Hotel & Suites Winona

12. Holiday Inn Express & Suites Winona by IHG

13. The Rushford Inn

14. Country Trails Inn & Suites

15. Spark by Hilton Rochester South

16. AmericInn by Wyndham Rochester Near Mayo Clinic

17. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

18. Econo Lodge Mayo Clinic Area

19. Comfort Inn & Suites Rochester South Mayo Clinic

20. Med City Inn & Suites - Mayo Clinic Area

Learn more about St. Charles

Top St. Charles Hotel Reviews

Kahler Grand Hotel

AmericInn by Wyndham Rochester Near Mayo Clinic

Hyatt House Rochester/Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Express Suites Riverport Inn & Suites

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Holiday Inn Express Rochester South - Mayo Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Kahler Inn and Suites - Mayo Clinic Area

More cheap stays in St. Charles

Birch Hill Suite Rochester – Med City

Super 8 by Wyndham Winona MN

Med City Inn & Suites - Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Brentwood Inn & Suites

Holiday Inn Express Rochester South - Mayo Area by IHG

Frequently asked questions

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