St. Charles Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
1 Aug - 2 Aug
Tomorrow
2 Aug - 3 Aug
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Filter by

Guest rating
Guest rating
Property class

Top 10 trending St. Charles hotels

Residence Inn by Marriott Rochester Mayo Clinic Area South
Relax by the fire pit surrounded by comfortable seating and lush greenery.

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
9.6 out of 10, Exceptional, (187)
"Has to be the cleanest hotel I have booked. I loved it here and will definitely be booking it again."
The price is €115
includes taxes & fees
9 Aug - 10 Aug
Residence Inn by Marriott Rochester Mayo Clinic Area South
Days Inn by Wyndham Winona
Lobby

Days Inn by Wyndham Winona

2.0 star property
7.8 out of 10, Good, (1002)
"Great stay, very clean and good service. "
The price is €78
includes taxes & fees
3 Aug - 4 Aug
Days Inn by Wyndham Winona
Fairfield Inn & Suites by Marriott Winona
Enjoy dining and socializing in this outdoor patio area with a large, round table and comfortable seating.

Fairfield Inn & Suites by Marriott Winona

2.5 star property
9.4 out of 10, Exceptional, (327)
"A very nice place to stay for a long weekend."
The price is €140
includes taxes & fees
10 Aug - 11 Aug
Fairfield Inn & Suites by Marriott Winona
White Valley Motel
Guests can enjoy a welcoming atmosphere on the front porch with a small table and potted plants.

White Valley Motel

2.5 star property
6.0 out of 10, (112)
"Nice location, looks good on the outside, easy parking, bed good, shower good, comfortable interior temperature and pleasant atmosphere (air), service very good. Negatives- toilet seat loose, bathroom door drags on floor, tv had lines through screen and refrigerator worked but bably yellowed. Overall would stay again because of good price, location and service."
The price is €67
includes taxes & fees
2 Aug - 3 Aug
White Valley Motel
Alexander Mansion Bed and Breakfast
Stunning staircase with ornate balustrades and carpeted landing, illuminated by a chandelier.

Alexander Mansion Bed and Breakfast

3.5 star property
9.8 out of 10, Exceptional, (463)
"Check in was great with the owner telling us about the history of the house. Breakfast was excellent!"
Alexander Mansion Bed and Breakfast
Carriage House B&B
Relax by the fire pit in a serene outdoor seating area surrounded by comfortable chairs and lush greenery.

Carriage House B&B

3.0 star property
9.8 out of 10, Exceptional, (86)
"Jan was very friendly and pleasant to speak with. Breakfasts were exceptionally tasteful and well presented. Other guests were very friendly and pleasant Highly recommend a stay here!"
The price is €121
includes taxes & fees
3 Aug - 4 Aug
Carriage House B&B
Super 8 by Wyndham Winona MN
Relax in a stylish space with a central TV, comfortable seating, and a convenient dining area.

Super 8 by Wyndham Winona MN

2.0 star property
7.6 out of 10, Good, (1002)
"We had a very nice stay "
The price is €60
includes taxes & fees
1 Sept - 2 Sept
Super 8 by Wyndham Winona MN
Express Suites Riverport Inn & Suites
Relax in a spacious living area with a comfortable seating area, flat-screen TV, and stone fireplace.

Express Suites Riverport Inn & Suites

3.0 star property
8.4 out of 10, Very good, (1000)
"Pool and hot tub were amazing and the breakfast was great!"
The price is €97
includes taxes & fees
3 Aug - 4 Aug
Express Suites Riverport Inn & Suites
Holiday Inn Express & Suites Winona by IHG
Enjoy a self-service dining experience with a variety of food options available.

Holiday Inn Express & Suites Winona by IHG

2.5 star property
9.0 out of 10, Wonderful, (852)
"Great location, modern features, good free breakfast with many options and friendly staff"
The price is €139
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express & Suites Winona by IHG
AmericInn by Wyndham Winona
Welcome to this American hotel, featuring a flat roof design and a red awning at the entrance.

AmericInn by Wyndham Winona

2.5 star property
9.0 out of 10, Wonderful, (824)
"Pleasant stay"
The price is €121
includes taxes & fees
17 Aug - 18 Aug
AmericInn by Wyndham Winona
The Plaza Hotel & Suites Winona
Enjoy meals in a shaded outdoor setting with comfortable seating and lush greenery.

The Plaza Hotel & Suites Winona

3.0 star property
8.8 out of 10, Excellent, (1000)
"Overall great location and restaurant connection to the hotel Pool is amazing "
The price is €156
includes taxes & fees
3 Aug - 4 Aug
The Plaza Hotel & Suites Winona
Big River Escape Parkside Bungalow
Family Cottage, Park View | Private kitchen

Big River Escape Parkside Bungalow

3.0 star property
The price is €173
includes taxes & fees
25 Aug - 26 Aug
Big River Escape Parkside Bungalow
The Wen Inn formerly Andor Wenneson
Welcome to Wenneson, where a charming entrance invites you to relax on the porch with a bench and wicker chair.

The Wen Inn formerly Andor Wenneson

2.0 star property
10.0 out of 10, Exceptional, (35)
"great property reasonably priced"
The price is €108
includes taxes & fees
3 Aug - 4 Aug
The Wen Inn formerly Andor Wenneson
Big River Escape Riverside Cabins
Cozy retreat with a dining table, kitchenette, and ceiling fan.

Big River Escape Riverside Cabins

3.0 star property
9.2 out of 10, Wonderful, (32)
"Beautiful stay"
The price is €112
includes taxes & fees
5 Aug - 6 Aug
Big River Escape Riverside Cabins
Stone Mill Hotel & Suites
Cozy interior space with a comfortable seating area, sofa, chairs, and staircase leading to an upper level.

Stone Mill Hotel & Suites

3.0 star property
9.2 out of 10, Wonderful, (626)
"Owner of the property so nice. Enjoyed our stay. "
The price is €99
includes taxes & fees
13 Aug - 14 Aug
Stone Mill Hotel & Suites
Country Trails Inn & Suites
Towels are neatly folded on a tiered metal chair against a wall with a blue and beige tile design.

Country Trails Inn & Suites

2.0 star property
9.4 out of 10, Exceptional, (78)
"Very Nice Staff friendly "
The price is €122
includes taxes & fees
3 Aug - 4 Aug
Country Trails Inn & Suites
Green Gables Inn
Exterior

Green Gables Inn

2.0 star property
9.8 out of 10, Exceptional, (14)
"Very quiet and home like."
The price is €116
includes taxes & fees
4 Aug - 5 Aug
Green Gables Inn
The Berkman
Relax in a shaded outdoor space with comfortable seating and a pergola.

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (324)
"Very nice place. Spacious rooms and generous staff. "
The price is €117
includes taxes & fees
2 Aug - 3 Aug
The Berkman
Big River Escape Grandview Manse
Enjoy a meal with a river view from this dining area, featuring a table and chairs.

Big River Escape Grandview Manse

3.0 star property
10.0 out of 10, Exceptional, (1)
"It was very roomy and easily accessible. The views were amazing. Would recommend to anyone anytime!!"
Big River Escape Grandview Manse
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Relax in the SPYHOUSE's outdoor seating area, surrounded by lush greenery and comfortable seating.

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
9.6 out of 10, Exceptional, (440)
"Our favorite place to stay when traveling to Mayo Clinic."
The price is €101
includes taxes & fees
29 Aug - 30 Aug
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles

Top St. Charles Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"The beds need to be lower at least 5 inches and be closer to the floor so a person don't need ladder to get into bed."
Charles and Mary 11-night trip
Posted 2 days ago
AmericInn by Wyndham Rochester Near Mayo Clinic

Frequently asked questions

Where is the best place to stay in St. Charles?

Based on Expedia's traveller preferences, White Valley Motel is a top place to stay in St. Charles. Two other options for your stay in the area are Kahler Grand Hotel and AmericInn by Wyndham Rochester Near Mayo Clinic. See all available top hotels, or vacation rentals in St. Charles.

What are some of the best holiday rentals that St. Charles has to offer?

Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!: This holiday home rental outside of St. Charles offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

What are some accommodation options with pools in St. Charles?

Kahler Inn and Suites - Mayo Clinic Area: 3.5-star hotel steps from Mayo Clinic. Offers a snack bar, an indoor pool and free WiFi. Even Hotel Rochester - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S are a couple of other choices that feature an on-site pool. View all hotels with pools in St. Charles.

What's it like to stay in St. Charles?

Visitors can enjoy all that St. Charles has to offer, including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 2 hotels and other accommodation options to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

A couple of favourite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.

What's the weather like in St. Charles?

The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.