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Top Hotels in Mississippi County
Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
Lana
The price is €66
includes taxes & fees
7 Dec - 8 Dec
Quality Inn Charleston - Sikeston
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
Arturo
The price is €63
includes taxes & fees
19 Dec - 20 Dec
Eagle Inn Charleston
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
David
The price is €58
includes taxes & fees
7 Dec - 8 Dec
Quality Inn Cairo I-57
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
Uma
The price is €67
includes taxes & fees
13 Dec - 14 Dec
Charming 3-bedroom house near ball park in quiet neighborhood
Bardwell
10.0 out of 10, Exceptional, (11)
"Quaint stay to see Grand and kids. "
Sheila C.
The price is €142
includes taxes & fees
6 Jan - 7 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews
Hampton Inn Sikeston
10/10 Excellent
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