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San Francisco Hotel Guide. Hotels in Downtown South San Francisco, San Francisco, United States of America

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Check prices for these dates

This weekend
21 Aug - 23 Aug
Next weekend
28 Aug - 30 Aug

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Our top choices for Downtown South San Francisco hotels

A La Quinta hotel with a modern facade, a covered entrance, and a parking lot.

1. La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very good, (2,141 reviews)
"Really clean and perfect place to stay in"
United States
Juan
The price is €126
includes taxes & fees
22 Aug - 23 Aug
La Quinta Inn & Suites by Wyndham San Francisco Airport N
A hotel room with a bed, a desk, a chair, a TV, and a lamp.

2. Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,005 reviews)
"Staff was friendly and breakfast was awesome!"
United States
Marco
The price is €73
includes taxes & fees
23 Aug - 24 Aug
Inn By The SFO
An indoor courtyard with a stone floor, a round table with chairs, and potted plants.

3. Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,008 reviews)
"I stay here often on my in person work days. Great location next to food and very friendly staff!"
United States
Kelly
The price is €106
includes taxes & fees
29 Aug - 30 Aug
Airport Inn
A neatly made bed with white linens and a folded towel, a wooden headboard, and a window with blinds.

4. Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (19 reviews)
"I liked the room"
United States
Lina
The price is €117
includes taxes & fees
23 Aug - 24 Aug
Miller Apartments
An outdoor patio with modern seating, a fire feature, and string lights.

5. Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side, 1.5 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,246 reviews)
"Great hotel to stay at, especially with kids"
United States
Lizset
The price is €100
includes taxes & fees
3 Sept - 4 Sept
Home2 Suites by Hilton San Francisco Airport North
A spacious, modern living area with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

6. DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
1.5 km from Downtown South San Francisco
8.4 out of 10, Very good, (2,428 reviews)
"Staff was amazing and the property was beautiful."
United States
Mokihana
The price is €131
includes taxes & fees
4 Sept - 5 Sept
DoubleTree by Hilton San Francisco South Airport Blvd
A bar area with a curved wooden counter, bar stools, and a glass display case filled with bottles.

7. Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
1.8 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,896 reviews)
"Location is perfect"
United States
Kenneth
The price is €109
includes taxes & fees
4 Sept - 5 Sept
Best Western Plus Grosvenor Airport Hotel
A multi-level hotel atrium with outdoor seating areas, a pool, and a central lounge.

8. Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side, 1.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,709 reviews)
"Great place would stay there again."
Canada
Alain
The price is €148
includes taxes & fees
6 Sept - 7 Sept
Embassy Suites by Hilton San Francisco Airport Oyster Point
A courtyard with outdoor seating, a glass table, and potted plants.

9. Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side, 1.1 km from Downtown South San Francisco
7.8 out of 10, Good, (1,005 reviews)
"Everything was perfect for the price"
United States
marie
The price is €102
includes taxes & fees
6 Sept - 7 Sept
Comfort Inn and Suites San Francisco Airport North
A hotel room with a bed, desk, chair, television, and a microwave.

10. Hotel Nova SFO

Hotel Nova SFO
2.5 star property
1.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,010 reviews)
"I had a great stay!"
United States
Brenden
The price is €117
includes taxes & fees
23 Aug - 24 Aug
Hotel Nova SFO

11. Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point, 2.2 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2,331 reviews)
"Great place to stay."
United States
Renato
The price is €115
includes taxes & fees
7 Sept - 8 Sept
Sonesta Select San Francisco Airport Oyster Point Waterfront
A hotel room with a large bed, a dining table, a chandelier, and a view of the city through the windows.

12. Villa Montes Hotel

Villa Montes Hotel
3.0 star property
3.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"We really enjoyed our stay. The room was clean and comfortable and the neighborhood felt safe. We look toward to staying here again in the future!"
United States
Anna
The price is €136
includes taxes & fees
22 Aug - 23 Aug
Villa Montes Hotel
A hotel room with a bed, a sofa, a nightstand, and a desk. There are three framed pictures on the wall.

13. The Atrium Hotel

The Atrium Hotel
2.5 star property
3 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,029 reviews)
"Nice compact and Ideal location & Excellent parking included"
Canada
SOHAIL
The price is €108
includes taxes & fees
23 Aug - 24 Aug
The Atrium Hotel
A modern interior with a wooden partition, a stone accent wall, and a bar area.

14. DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront
4.0 star property
3.1 km from Downtown South San Francisco
8.2 out of 10, Very good, (1,709 reviews)
"A nice quiet hotel."
United States
Miguel
The price is €99
includes taxes & fees
7 Sept - 8 Sept
DoubleTree by Hilton San Francisco Airport North Bayfront
A hotel room with a bed, bedside tables, a desk, a chair, and a large window.

15. Gateway Inn & Suites San Francisco SFO Airport

Gateway Inn & Suites San Francisco SFO Airport
2.0 star property
3.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,050 reviews)
"Booked because of location near airport and price."
United States
david
The price is €80
includes taxes & fees
23 Aug - 24 Aug
Gateway Inn & Suites San Francisco SFO Airport
A spacious, well-lit atrium with a high ceiling and skylight, featuring a central seating area with a sofa and armchairs, surrounded by a patterned rug.

16. Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
3.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (3,068 reviews)
"Overall great place to stay"
United States
Cong
The price is €101
includes taxes & fees
23 Aug - 24 Aug
Hotel Aluxor SFO
A modern hotel bathroom with a large mirror, a sink, and a coffee machine. There is a small table and a bed in the adjacent room.

17. Hotel Skye SFO

Hotel Skye SFO
3.0 star property
3.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,946 reviews)
"Clean room, helpful staff, big ups to them for offering free parking near the airport!"
Canada
Joyal
The price is €110
includes taxes & fees
23 Aug - 24 Aug
Hotel Skye SFO
A spacious lobby with a reception desk, seating area, and a high ceiling with chandeliers.

18. La Quinta Inn & Suites by Wyndham San Francisco Airport West

La Quinta Inn & Suites by Wyndham San Francisco Airport West
3.0 star property
5.4 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,809 reviews)
"Clean room , breakfast was great !"
United States
Maria
The price is €139
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham San Francisco Airport West
A reception area with a counter, two patterned chairs, a yellow ottoman, and a large blue potted plant.

19. Hotel Aura SFO

Hotel Aura SFO
3.0 star property
4.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,662 reviews)
"Great hotel , great customer service, highly recommended if you want to stay around locals , also Close to the airport."
United States
Andres
The price is €127
includes taxes & fees
20 Sept - 21 Sept
Hotel Aura SFO
A modern living room with a green wall, a sofa, a coffee table, a bookshelf, and a lamp.

20. The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,886 reviews)
"Such a great location and experience."
United States
Stacy
The price is €134
includes taxes & fees
4 Sept - 5 Sept
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Soak up the atmosphere of bygone days on this historic wharf where the emphasis is still firmly on seafood.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Hilton San Francisco Union Square

Hilton San Francisco Union Square

10/10 Excellent
"Front staff who assisted check-in was quite helpful with niche situation. He was kind, and performed his job above and beyond. Mattress in my room seemed brand new and all the sheets were clean. There was everything provided you would need other than a sewing kit or toothbrush & showercap but honestly, i didnt need those."
Jennifer 2-night trip
Posted 1 hour ago
Hilton San Francisco Union Square

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Francisco Airport N is one of the top choices for your stay in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 10 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed San Francisco are also worth a visit when you're out sightseeing in South San Francisco.