San Francisco Hotel Guide. Hotels in Downtown South San Francisco, San Francisco, United States of America

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (1,979 reviews)
"quiet, near eateries, clean"
United States
Raul
The price is €115
includes taxes & fees
30 Mar - 31 Mar
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (996 reviews)
"Decent for the price. Very clean."
United States
Ronald
The price is €104
includes taxes & fees
27 Mar - 28 Mar
Airport Inn

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.0 out of 10, Good, (16 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is €122
includes taxes & fees
30 Mar - 31 Mar
Miller Apartments

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,004 reviews)
" TV and phone were not working in the room. Room was clean and this is a good location near the airport with free parking. But if you need more than a bed to sleep I’d go somewhere else. "
United States
Kelly
Inn By The SFO

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,247 reviews)
"Great place"
Canada
Mark
The price is €100
includes taxes & fees
4 Apr - 5 Apr
Aloft San Francisco Airport

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
16.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7,388 reviews)
"Clean rooms, great staff, perfect location"
United States
Alexis
The price is €185
includes taxes & fees
12 Apr - 13 Apr
Hotel Riu Plaza Fisherman's Wharf

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.9 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,953 reviews)
"Nice reception quick and efficient! Great breakfast and good restaurant. Starbucks is a plus. "
United States
Lucila
The price is €151
includes taxes & fees
4 Apr - 5 Apr
The Westin San Francisco Airport

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,363 reviews)
"Great place "
United States
ILiana
The Marina Inn on San Francisco Bay

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
9.3 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,489 reviews)
"Very nice hotel, clean, Starbucks onsite, and great breakfast choices."
United States
Fritz Lou
The price is €98
includes taxes & fees
3 Apr - 4 Apr
DoubleTree by Hilton San Francisco Airport

The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,849 reviews)
"Frequently stay at this property (over 25yrs) never disappoints!"
United States
Robert
The price is €117
includes taxes & fees
28 Mar - 29 Mar
The Dylan at SFO

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
16.8 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,487 reviews)
"Great location "
United States
Ramona
The price is €189
includes taxes & fees
30 Mar - 31 Mar
Hotel Zephyr San Francisco

Vagabond Inn Executive San Francisco Airport

Vagabond Inn Executive San Francisco Airport
2.5 star property
7.6 km from Downtown South San Francisco
8.0 out of 10, Very good, (1,008 reviews)
"The property was nice. The staff was very friendly."
United States
Shaquille
The price is €104
includes taxes & fees
27 Mar - 28 Mar
Vagabond Inn Executive San Francisco Airport

Cow Hollow Inn & Suites

Cow Hollow Inn & Suites
3.5 star property
16 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,542 reviews)
"The room we had was spacious, clean and the staff was exceptionally friendly and helpful."
United States
Elizabeth
Cow Hollow Inn & Suites

Hotel Aura SFO

Hotel Aura SFO
3.0 star property
4.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,597 reviews)
"Great room and accommodation. Friendly staff. "
United States
Richard
The price is €107
includes taxes & fees
12 Apr - 13 Apr
Hotel Aura SFO

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown
3.0 star property
13.7 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (2,060 reviews)
"Clean and updated rooms with a great breakfast option "
United States
Courtney
The price is €202
includes taxes & fees
29 Mar - 30 Mar
Hyatt Place San Francisco Downtown

Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
3.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,862 reviews)
"Very nice hotel in a great location."
United States
Arloene
Hotel Aluxor SFO

Hampton Inn & Suites Oakland Airport-Alameda

Hampton Inn & Suites Oakland Airport-Alameda
2.5 star property
17.1 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,006 reviews)
"Excellent experience for an airport area hotel. We would stay again! "
United States
Darcy
The price is €109
includes taxes & fees
24 Apr - 25 Apr
Hampton Inn & Suites Oakland Airport-Alameda

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
16.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3,861 reviews)
"Staff was wonderful. Located close to a lot of tourist attractions. Housekeeping was wonderful. "
United States
Shawn
The price is €172
includes taxes & fees
12 Apr - 13 Apr
Hotel Caza Fisherman's Wharf

Marina Village Inn

Marina Village Inn
2.0 star property
19.4 km from Downtown South San Francisco
7.4 out of 10, Good, (1,004 reviews)
"the room was clean staff r so nice super easy check in and check out "
United States
Alannah
The price is €84
includes taxes & fees
1 Apr - 2 Apr
Marina Village Inn

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
13.3 km from Downtown South San Francisco
9.6 out of 10, Exceptional, (2,429 reviews)
"Clean room, great location and superb staff. "
United States
Brenda
The price is €243
includes taxes & fees
29 Mar - 30 Mar
LUMA Hotel San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

Fisherman's Wharf

Soak up the atmosphere of bygone days on this historic wharf where the emphasis is still firmly on seafood.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favourite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.