San Francisco Hotel Guide. Hotels in Downtown South San Francisco, San Francisco, United States of America

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2,024 reviews)
"Awsome rooms clean overall great experience "
United States
manuel
The price is €100
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (979 reviews)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is €98
includes taxes & fees
24 Feb - 25 Feb
Airport Inn

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"Everything great. Good location close to airport and walking distance to coffee, market, and restaurants. Try shabu shack!"
United States
Gabriel
Inn By The SFO

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is €156
includes taxes & fees
7 Feb - 8 Feb
Miller Apartments

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
16.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7,302 reviews)
"Great hotel "
United States
Gino
The price is €153
includes taxes & fees
25 Jan - 26 Jan
Hotel Riu Plaza Fisherman's Wharf

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
15.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2,325 reviews)
"We loved our stay! "
United States
Christine
The price is €106
includes taxes & fees
1 Feb - 2 Feb
Hilton San Francisco Financial District

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
16.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3,825 reviews)
"Nice place to stay"
United States
Harold Franklin
The price is €169
includes taxes & fees
23 Feb - 24 Feb
Hotel Caza Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
16.6 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,683 reviews)
"Very nice hotel and perfect location. "
United States
Syed
The price is €145
includes taxes & fees
10 Feb - 11 Feb
Hotel Zoe Fisherman's Wharf

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
16.8 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,389 reviews)
"The balcony view was amazing and parking was perfect. "
United States
Ena M
The price is €159
includes taxes & fees
28 Jan - 29 Jan
Hotel Zephyr San Francisco

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
9.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,892 reviews)
"The room and breakfast was perfect "
United States
Daniel
The price is €97
includes taxes & fees
15 Feb - 16 Feb
Hilton San Francisco Airport Bayfront

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
9.3 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,440 reviews)
"Very nice hotel"
United States
Mary Ann
The price is €100
includes taxes & fees
30 Jan - 31 Jan
DoubleTree by Hilton San Francisco Airport

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
15.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,922 reviews)
"nice location"
United Kingdom
Natthaya
The price is €107
includes taxes & fees
16 Feb - 17 Feb
Club Quarters Hotel in San Francisco

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
14.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (5,169 reviews)
"Great stay!"
United States
Carlos Emiro
The price is €119
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Golden Gateway by IHG

King George Hotel

King George Hotel
3.0 star property
14.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,098 reviews)
"The staff were all friendly and courteous, the room and bathroom were very clean, the beds were comfortable and a very good location."
United States
Jamie
The price is €100
includes taxes & fees
29 Jan - 30 Jan
King George Hotel

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,287 reviews)
"Clean room, courteous staff, break fast and great location."
United States
Claudia
The price is €156
includes taxes & fees
10 Feb - 11 Feb
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
14.5 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2,846 reviews)
"Great location, room was clean and staff was helpful."
United States
Laura
The price is €149
includes taxes & fees
25 Jan - 26 Jan
Handlery Union Square Hotel

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
14.7 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (3,161 reviews)
"Everything and everyone made the stay amazing"
United States
Angela
The price is €116
includes taxes & fees
22 Feb - 23 Feb
Chancellor Hotel on Union Square

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown
3.0 star property
13.7 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (1,955 reviews)
"Great overall stay, friendly staff"
United States
Brian
The price is €160
includes taxes & fees
20 Feb - 21 Feb
Hyatt Place San Francisco Downtown

Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
3.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,698 reviews)
"Nice place, would stay again "
United States
Alondra
Hotel Aluxor SFO

The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,842 reviews)
"great hotel, well designed, comfortable beds, easy access to the bart and aiport"
United States
Alan
The price is €110
includes taxes & fees
25 Jan - 26 Jan
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Soak up the atmosphere of bygone days on this historic wharf where the emphasis is still firmly on seafood.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favourite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 14 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
See's Candies, Cinemark Century at Tanforan and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.