What's it like in East End?

Travellers will be sure to find plenty to entertain them in Sanibel's East End neighbourhood. Make sure that you visit Sanibel Island Northern Beach and Sanibel Island Lighthouse as part of your East End travel plans.

Where is the best place to stay in East End?

Based on Expedia customer reviews, Tarpon Tale Inn is the highest ranked property in East End. This hotel is a short 6-minute walk from Sanibel Island Southern Beach, and it offers free parking and private patios. Other top choices in the neighbourhood include Sanibel Inn and Sunshine Island Inn .

How many hotels will I find in the East End area?

Expedia has 562 hotels and other accommodation options in East End to choose from, making this an ideal home base for exploring the greater Sanibel area.

If I need to cancel my hotel reservation in East End, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to view top deals in East End.

What are the top things to see and do in East End?

Dip your toes in the water at Sanibel Island Northern Beach, Sanibel Island Southern Beach and Causeway Islands Beaches while you're in East End. Sanibel Island Lighthouse and Periwinkle Way are also a couple of places to visit in the neighbourhood. Sanibel Sea School, Sanibel Moorings Botanical Gardens and Bailey's Beach are just a few of the places to visit in and around East End. Dunes Golf and Tennis Club and Causeway Islands Park B are also worth a visit when you're out sightseeing in Sanibel.

Sanibel Hotel Guide. Hotels in East End, Sanibel, United States of America

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January 2026

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February 2026

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Our top choices for East End hotels

Sanibel Inn

East End

Sandra

includes taxes & fees

1 Feb - 2 Feb

Tarpon Tale Inn

East End

John

includes taxes & fees

19 Jan - 20 Jan

Matlacha on Shoreview

21.5 km from East End

Michael

includes taxes & fees

19 Jan - 20 Jan

The Westin Cape Coral Resort At Marina Village

10.7 km from East End

Nicole

includes taxes & fees

1 Feb - 2 Feb

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

26 km from East End

Maitte

includes taxes & fees

18 Jan - 19 Jan

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

17.6 km from East End

Blaine

includes taxes & fees

18 Jan - 19 Jan

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

14.7 km from East End

Samanta

includes taxes & fees

25 Jan - 26 Jan

Dolphin Key Resort

15.1 km from East End

ROBERT

includes taxes & fees

15 Jan - 16 Jan

In-room safe, desk, laptop workspace, blackout curtains

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

15.3 km from East End

Anastassia

includes taxes & fees

18 Jan - 19 Jan

2 outdoor pools, pool cabanas (surcharge), pool umbrellas

The Perry Hotel Naples

29.3 km from East End

Linda Messana

includes taxes & fees

9 Feb - 10 Feb

Embassy Suites by Hilton Fort Myers Estero

24.8 km from East End

Laszlo

includes taxes & fees

20 Jan - 21 Jan

SpringHill Suites by Marriott Fort Myers Estero

24.7 km from East End

John

includes taxes & fees

25 Jan - 26 Jan

DoubleTree Suites by Hilton Naples

29.3 km from East End

Adam

includes taxes & fees

24 Jan - 25 Jan

Desk, blackout curtains, iron/ironing board, free cots/infant beds

TownePlace Suites by Marriott Fort Myers Estero

23 km from East End

Pamela

includes taxes & fees

23 Jan - 24 Jan

3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Hyatt Vacation Club at Coconut Cove, Bonita Springs

19.7 km from East End

Jan Pontus

includes taxes & fees

22 Jan - 23 Jan

Drury Inn & Suites Fort Myers Airport FGCU

24.3 km from East End

Robert

includes taxes & fees

25 Jan - 26 Jan

Hampton Inn & Suites Fort Myers-Estero/FGCU

25 km from East End

Caitriona

includes taxes & fees

19 Jan - 20 Jan

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

26.9 km from East End

Matthew

includes taxes & fees

18 Jan - 19 Jan

Fairfield Inn & Suites by Marriott Bonita Springs

30 km from East End

Jerry

includes taxes & fees

18 Jan - 19 Jan

Shangri-La Springs

27.9 km from East End

Elizabeth

View all properties

Where to stay in East End

Find the best East End areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

See properties

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

See properties

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

See properties

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

See properties

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

See properties

Top East End Hotel Reviews

Sanibel Inn

10/10 Excellent

"Yes, the room was Wonderful "

Tarpon Tale Inn

10/10 Excellent

"We had a short 2 day stay in Sanibel, and Tarpon Tale was the perfect spot for our family of 4. Easily walkable to some dining, shopping, and nice beaches, and the complimentary bikes give you the ability to explore the whole island while leaving the car parked. The extra details of this small independent hotel (bikes, shell-washing stations, fire pit area) are a great match for the small town, friendly feel of the island. Highly recommend"

1105 Skiff- Gorgeous ground level canal home

10/10 Excellent

"This property is amazing and in the best location. So very clean and stylish. Had everything we needed for our stay. Check-in and check-out process was very easy. Communication with Host was great. Would definitely recommend a stay on and we are already talking about our next trip there. It was perfect. "

Seahorse Suites #3. Island Living at it's Best!

10/10 Excellent

"The apartment is ideally located - short walk to the beach, and restaurants right across the street (and a deli below the apartment). Bikes available and an outdoor space for games. There are still some drainage issues around the island, so the walkway to the beach at the end of the street was under water from recent rain (we saw this in other parts of the island, too). Beds were comfortable and everything was clean. Thank you for a nice weekend! "

Seahorse Suites #2. Fun,Beach, Games, Memories!

10/10 Excellent

"We enjoyed our stay! Condo was the perfect size for a family of 3-4 people. We loved it! Property is close to the stores and the beach. The on-property bikes were fun to ride around the island. Our host checked in on us, which was nice. We will definitely be back!"

Sanibel Hotel Guide. Hotels in East End, Sanibel, United States of America

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for East End hotels

Sanibel Inn

Tarpon Tale Inn

Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Dolphin Key Resort

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

The Perry Hotel Naples

Embassy Suites by Hilton Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero

DoubleTree Suites by Hilton Naples

TownePlace Suites by Marriott Fort Myers Estero

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Drury Inn & Suites Fort Myers Airport FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

Fairfield Inn & Suites by Marriott Bonita Springs

Shangri-La Springs

Where to stay in East End

Mid Island

West End

Beachview Country Club Estates

Sanctuary

Shell Harbor

Top East End Hotel Reviews

Sanibel Inn

Frequently asked questions