
Medical Center District Holidays
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Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District

Downtown San Antonio
4 out of top 10 points of interest in this area
4.5/5(42 area reviews)
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.
Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is €84 per night from 23 Apr to 24 Apr
€84
23 Apr - 24 Apr
includes taxes & fees
8.4/10 Very Good! (3,238 reviews)
Room was clean but no information regarding restaurants or anything in the area. Front checking person was not friendly at all.
Reviewed on 28 Mar 2026

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is €111 per night from 16 Apr to 17 Apr
€111
16 Apr - 17 Apr
includes taxes & fees
8.6/10 Excellent! (1,004 reviews)
Bar was out of some items pools was clean and nice
Reviewed on 27 Mar 2026

Park Inn by Radisson
7500 Louis Pasteur Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is €65 per night from 27 Apr to 28 Apr
€65
27 Apr - 28 Apr
includes taxes & fees
7.2/10 Good! (1,000 reviews)
Close to my destination, clean, quiet.
Reviewed on 23 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
USAA Corporate Office Headquarters
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
Things to do

San Antonio: Fredericksburg Wineries Day Trip with Tastings
€154
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.





