Medical Center District

San Antonio

Photo by Linda Cronan

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is €85 per night from 1 Dec to 2 Dec
€85
1 Dec - 2 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,052 reviews)
Are go to hotel when we visit San Antonio. Quiet and staff are very polite. Breakfast is good with a good variety to choose from.

Reviewed on 13 Nov 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is €87 per night from 30 Nov to 1 Dec
€87
30 Nov - 1 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,002 reviews)
Room didnt seem to get serviced in the two night stay.

Reviewed on 12 Nov 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road San Antonio TX
The price is €84 per night from 1 Dec to 2 Dec
€84
1 Dec - 2 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,004 reviews)
Na

Reviewed on 10 Nov 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is €91 per night from 21 Dec to 22 Dec
€91
21 Dec - 22 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,002 reviews)
Room was clean, staff was very friendly!!

Reviewed on 19 Nov 2025

Courtyard by Marriott Medical Center San Antonio
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham San Antonio TX
The price is €83 per night from 23 Nov to 24 Nov
€83
23 Nov - 24 Nov
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,498 reviews)
The hotel was a lot of fun! The hotel's history was fascinating. The staff was great, and the room was perfect, being just a stone's throw from the River Walk.

Reviewed on 18 Nov 2025

Crockett Hotel
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is €132 per night from 18 Dec to 19 Dec
€132
18 Dec - 19 Dec
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (2,135 reviews)
There wasn’t any complementary breakfast which I found crazy. The AC wouldn’t get as cold as we had set it. The TV cable wasn’t plugged in and we had to call the front desk to be told to do it, again slot of money for TV not just be ready to go. It would’ve been nice if the staff let us know we have ...

Reviewed on 17 Nov 2025

Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown


Medical Center District

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