What is Medical Center District like?

Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.

What's a favourite hotel to stay in Medical Center District?

Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Drury Inn & Suites San Antonio Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio .

How many hotels will I be able to find in Medical Center District?

Expedia has 124 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.

What can I see and do in this San Antonio neighbourhood?

Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

Medical Center District hotels, San Antonio, United States of America: San Antonio Hotel Guide

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Our top choices for Medical Center District hotels

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

1. Courtyard by Marriott Medical Center San Antonio

Medical Center District

Francisca

includes taxes & fees

30 Oct - 31 Oct

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

2. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District

Jennifer

includes taxes & fees

5 Nov - 6 Nov

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

3. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District

Freddie

includes taxes & fees

8 Nov - 9 Nov

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District

Gilbert

includes taxes & fees

20 Oct - 21 Oct

A spacious lobby with a central staircase, seating area, and large windows.

5. San Antonio Marriott Northwest Medical Center

Medical Center District

Jan

includes taxes & fees

18 Nov - 19 Nov

A modern kitchen with a large window, wooden counter, and two bar stools.

6. Park Inn by Radisson, Medical Center

Medical Center District

Jaime

includes taxes & fees

19 Nov - 20 Nov

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District

Ruben

includes taxes & fees

27 Oct - 28 Oct

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

8. Atria Inn & Suites

Medical Center District

Jose Rolando

includes taxes & fees

14 Nov - 15 Nov

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

9. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District

robert

includes taxes & fees

23 Oct - 24 Oct

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

10. OYO Inn & Suites Medical Center San Antonio

Medical Center District

Melanie

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

11. Flex Studios

Medical Center District

Jasper

includes taxes & fees

2 Nov - 3 Nov

A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

12. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Medical Center District

Jerron

includes taxes & fees

20 Oct - 21 Oct

A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

3.7 km from Medical Center District

Alejandra

includes taxes & fees

29 Oct - 30 Oct

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and palm trees in the landscaping.

14. Hampton Inn & Suites San Antonio Northwest/Medical Center

Northwest Side, 4.7 km from Medical Center District

Efrain

includes taxes & fees

15 Nov - 16 Nov

A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

15. Best Western Medical Center North Inn & Suites Near Six Flags

Northwest Side, 5.2 km from Medical Center District

Jesus

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

16. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9.5 km from Medical Center District

susan

includes taxes & fees

25 Oct - 26 Oct

A modern breakfast bar with a menu board, a coffee machine, and a variety of breakfast items displayed.

17. Courtyard by Marriott San Antonio Lackland

6.5 km from Medical Center District

Janel

includes taxes & fees

25 Oct - 26 Oct

A circular stone fire pit with two wooden benches, surrounded by a stone patio and string lights.

18. Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Far West Side, 11.3 km from Medical Center District

Evan

includes taxes & fees

16 Nov - 17 Nov

A spacious lobby with a modern design, featuring a large seating area with sofas and armchairs, a patterned rug, and a reception desk.

19. Comfort Inn and Suites Near Medical Center

4.6 km from Medical Center District

Anayeli

includes taxes & fees

2 Nov - 3 Nov

A modern kitchen with a wooden countertop, a coffee station, and a food display.

20. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

7.7 km from Medical Center District

Sonaida

includes taxes & fees

25 Oct - 26 Oct

View all properties

Compare popular hotels in Medical Center District

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	3.0 star property	9.2 Wonderful 1,505 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	3.0 star property	9.0 Wonderful 1,105 reviews	View
Courtyard by Marriott Medical Center San Antonio	3.0 star property	8.8 Excellent 1,003 reviews	View
San Antonio Marriott Northwest Medical Center	3.5 star property	8.6 Excellent 1,179 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	3.0 star property	8.4 Very good 3,730 reviews	View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

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Top Medical Center District Hotel Reviews

Hotel Valencia Riverwalk

10/10 Excellent

"Excellent value on riverwalk."

Drury Inn & Suites San Antonio Northwest Medical Center

10/10 Excellent

"The building and rooms are not brand new, but everything else was great. The staff was very friendly and helpful. There's plenty of parking and it's free. The indoor pool and jacuzzi was awesome. And the the best part for me was the complimentary breakfast and happy hour (3 drinks per person + lot's of options of food like nachos, hotdog, salad, baked potato, pulled pork, beans, etc.)"

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

10/10 Excellent

"Great staff with clean and well maintained rooms. Breakfast was good but the staff had difficulty keeping up with demand. However, it was a very busy weekend. We had an issue and maintenance was immediately on it. Great stay overall."

San Antonio Hotel Guide. Hotels in Medical Center District, San Antonio, United States of America

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Our top choices for Medical Center District hotels

1. Courtyard by Marriott Medical Center San Antonio

2. Drury Inn & Suites San Antonio Northwest Medical Center

3. Fairfield Inn & Suites by Marriott San Antonio Medical Center

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. San Antonio Marriott Northwest Medical Center

6. Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. Atria Inn & Suites

9. Motel 6 San Antonio, TX - Northwest Medical Center

10. OYO Inn & Suites Medical Center San Antonio

11. Flex Studios

12. Studio 6 Extended Stay - San Antonio, TX - Medical Center

13. Hyatt Place San Antonio-Northwest/Medical Center

14. Hampton Inn & Suites San Antonio Northwest/Medical Center

15. Best Western Medical Center North Inn & Suites Near Six Flags

16. Drury Inn & Suites Near La Cantera Parkway

17. Courtyard by Marriott San Antonio Lackland

18. Hyatt Vacation Club at Wild Oak Ranch, San Antonio

19. Comfort Inn and Suites Near Medical Center

20. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Compare popular hotels in Medical Center District

Where to stay in Medical Center District

Downtown San Antonio

Far West Side

Uptown Central

Northwest Side

Stone Oak

Top Medical Center District Hotel Reviews

Hotel Valencia Riverwalk

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