
San Antonio Hotel Guide. Hotels in Medical Center District, San Antonio, United States of America
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District
8.6 out of 10, Excellent, (1,076 reviews)
The price is €110
includes taxes & fees
12 Jul - 13 Jul

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District
8.4 out of 10, Very good, (3,426 reviews)
The price is €91
includes taxes & fees
15 Jun - 16 Jun

Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District
9.2 out of 10, Wonderful, (1,353 reviews)
The price is €92
includes taxes & fees
6 Jul - 7 Jul

Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District
8.8 out of 10, Excellent, (1,002 reviews)
The price is €91
includes taxes & fees
26 Jun - 27 Jun

Park Inn by Radisson
Park Inn by RadissonMedical Center District
7.2 out of 10, Good, (1,002 reviews)
The price is €68
includes taxes & fees
26 Jun - 27 Jun

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical CenterMedical Center District
9.0 out of 10, Wonderful, (1,013 reviews)
The price is €87
includes taxes & fees
21 Jun - 22 Jun

OYO Inn & Suites Medical Center San Antonio
OYO Inn & Suites Medical Center San AntonioMedical Center District
7.4 out of 10, Good, (238 reviews)
The price is €61
includes taxes & fees
26 Jun - 27 Jun

Studio 6 Extended Stay - San Antonio, TX - Medical Center
Studio 6 Extended Stay - San Antonio, TX - Medical CenterMedical Center District
6.8 out of 10, (912 reviews)
The price is €53
includes taxes & fees
14 Jun - 15 Jun

Flex Studios
Flex StudiosMedical Center District
6.0 out of 10, (541 reviews)
The price is €40
includes taxes & fees
23 Jun - 24 Jun

Motel 6 San Antonio, TX - Northwest Medical Center
Motel 6 San Antonio, TX - Northwest Medical CenterMedical Center District
6.0 out of 10, (1,002 reviews)
The price is €51
includes taxes & fees
14 Jun - 15 Jun

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Country Inn & Suites by Radisson, San Antonio Medical Center, TXMedical Center District
7.0 out of 10, Good, (1,001 reviews)
The price is €63
includes taxes & fees
21 Jun - 22 Jun

Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, Tx - Northwest Medical CenterMedical Center District
7.4 out of 10, Good, (300 reviews)
The price is €47
includes taxes & fees
21 Jun - 22 Jun

Atria Inn & Suites
Atria Inn & SuitesMedical Center District
7.4 out of 10, Good, (296 reviews)
The price is €63
includes taxes & fees
13 Jun - 14 Jun

Best Western Plus Atrium Inn
Best Western Plus Atrium Inn30.6 km from Medical Center District
8.6 out of 10, Excellent, (1,003 reviews)
The price is €84
includes taxes & fees
14 Jun - 15 Jun

Extended Stay America Premier Suites - San Antonio - Schertz
Extended Stay America Premier Suites - San Antonio - Schertz29.4 km from Medical Center District
9.2 out of 10, Wonderful, (306 reviews)
The price is €90
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn & Suites Selma-San Antonio-Randolph AFB Texas
Hampton Inn & Suites Selma-San Antonio-Randolph AFB TexasLive Oak, 25 km from Medical Center District
9.2 out of 10, Wonderful, (1,003 reviews)
The price is €77
includes taxes & fees
8 Jul - 9 Jul

Best Western Garden Inn
Best Western Garden InnUptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,003 reviews)
The price is €69
includes taxes & fees
14 Jun - 15 Jun

Drury Inn & Suites San Antonio Northeast
Drury Inn & Suites San Antonio Northeast17.6 km from Medical Center District
9.4 out of 10, Exceptional, (1,001 reviews)
The price is €89
includes taxes & fees
16 Jun - 17 Jun

Holiday Inn Express & Suites San Antonio North - Windcrest by IHG
Holiday Inn Express & Suites San Antonio North - Windcrest by IHG17.5 km from Medical Center District
9.0 out of 10, Wonderful, (1,005 reviews)
The price is €100
includes taxes & fees
28 Jun - 29 Jun

Comfort Suites San Antonio Ft. Sam Houston/SAMMC Area
Comfort Suites San Antonio Ft. Sam Houston/SAMMC Area17.2 km from Medical Center District
9.2 out of 10, Wonderful, (967 reviews)
The price is €90
includes taxes & fees
21 Jun - 22 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Medical Center District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,353 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott San Antonio Medical Center | 9.0 Wonderful 1,013 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,002 reviews | View | ||||||
![]() San Antonio Marriott Northwest Medical Center | 8.6 Excellent 1,076 reviews | View | ||||||
![]() La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW | 8.4 Very good 3,426 reviews | View |
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Alamo Quarry Market are top sights worth seeing.

Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in West San Antonio
- Alamo Heights Hotels
- Hotels near Alamo
- Hotels near Alamodome
- Beacon Hill Hotels
- Blossoms Park Hotels
- Hotels near Blue Star Art Space Museum
- Downtown San Antonio Hotels
- East Terrell Hills Hotels
- Helotes Hotels
- Hotels near Henry B. González Convention Center
- Historic Garderns Hotels
- Hollywood Park Hotels
- Hotels near Lackland Air Force Base
- Hotels near Lackland Air Force Base Visitor Center
- Mission Trace Hotels
- Monticello Park Hotels
- Business Hotels in North San Antonio - SAT
- Green / Sustainable Hotels in North San Antonio - SAT
- Hotels with Pool in North San Antonio - SAT
- Pearl District Hotels
- Hotels near River Walk
- Resorts in San Antonio
- Cheap Hotels in San Antonio
- Family Friendly Hotels in San Antonio
- Historic Hotels in San Antonio
- Hotels with Connecting Rooms in San Antonio
- Hotels with WiFi in San Antonio
- Luxury Hotels in San Antonio
- Starwood Capital Hotels in San Antonio
- San Antonio Hotels
- Hotels near San Antonio Intl.
- Holiday Homes in San Antonio
- Hotels near San Antonio Zoo and Aquarium
- Hotels near Six Flags Fiesta Texas
- South San Antonio Hotels
- The Dominion Hotels
- Hotels near USAA Corporate Office Headquarters
- Drury Inn & Suites Hotels in West San Antonio
- Golf Hotels in West San Antonio
- Red Lion Hotels in West San Antonio
- Windcrest Hotels
- Flights to San Antonio
- Flights from Nashville (BNA) to San Antonio (SAT)
- Flights from Boston (BOS) to San Antonio (SAT)
- Flights from Cincinnati (CVG) to San Antonio (SAT)
- Flights from Washington (DCA) to San Antonio (SAT)
- Flights from Dallas (DFW) to San Antonio (SAT)
- Flights from Dublin (DUB) to San Antonio (SAT)
- Flights from Eagle Pass (EGP) to San Antonio (SAT)
- Flights from Guadalajara (GDL) to San Antonio (SAT)
- Flights from Houston (IAH) to San Antonio (SAT)
- Flights from Ibiza (IBZ) to San Antonio (SAT)
- Flights from New York (JFK) to San Antonio (SAT)
- Flights from Kiruna (KRN) to San Antonio (SAT)
- Flights from Las Vegas (LAS) to San Antonio (SAT)
- Flights from Lexington (LEX) to San Antonio (SAT)
- Flights from Madrid (MAD) to San Antonio (SAT)
- Flights from Orlando (MCO) to San Antonio (SAT)
- Flights from Mexico City (MEX) to San Antonio (SAT)
- Flights from Mount Pleasant (MPN) to San Antonio (SAT)
- Flights from Monterrey (MTY) to San Antonio (SAT)
- Flights from New York (NYC) to San Antonio (SAT)
- Flights from Philadelphia (PHL) to San Antonio (SAT)
- Flights from Punta Gorda (PND) to San Antonio (SAT)
- Flights from Charlotte (QWG) to San Antonio (SAT)
- Flights from Reno (RNO) to San Antonio (SAT)
- Flights from Rawlins (RWL) to San Antonio (SAT)
- Flights from Santiago (SCL) to San Antonio (SAT)
- Flights from San Francisco (SFO) to San Antonio (SAT)
- Flights from Shannon (SNN) to San Antonio (SAT)
- Flights from Zagreb (ZAG) to San Antonio (SAT)
- Alamo
- Visit Alamo Plaza
- Alamo Quarry Market
- Belmeade Park
- Harry B Orem Stadium
- Ingram Park Mall
- Lackland Air Force Base Visitor Center
- Visit Downtown San Antonio
- Visit Far West Side
- Visit Main - Military Plaza
- Visit Midtown
- Visit Westfort
- San Antonio Zoo and Aquarium
- San Pedro Driving Range & Par 3 Course
- Usaa Corporate Office Headquarters
- Witte Museum




























































































