Mission District Holidays

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Price found within the past 48 hours. Click for updated prices.
Nob Hill Hotel

Nob Hill Hotel

4 out of 5
Downtown San Francisco
Price was €613, price is now €463 per person
€463
per person
13 Feb - 17 Feb
found 17 hours ago
Return flight included
Philadelphia (PHL) to San Francisco (SFO)
7.8/10 Good! (1,004 reviews)
It is close to everything!

Reviewed on 8 Jan 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was €783, price is now €527 per person
€527
per person
13 Feb - 17 Feb
found 17 hours ago
Return flight included
Philadelphia (PHL) to San Francisco (SFO)
9/10 Wonderful! (7,092 reviews)
Clean room. Courteous staff. Good breakfast buffet. All around great stay. Will definitely go back

Reviewed on 11 Jan 2026

The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
Union Square
Price was €782, price is now €577 per person
€577
per person
13 Feb - 17 Feb
found 17 hours ago
Return flight included
Philadelphia (PHL) to San Francisco (SFO)
9/10 Wonderful! (1,052 reviews)
The Marker Union Square San Francisco was a wonderful stay. The customer service was excellent, the rooms were very clean, and the entire hotel had a beautiful Christmas atmosphere. The evening carolers were such a special touch and truly made the experience memorable. I would definitely stay here again and highly recommend it.🌟🌟🌟🌟

Reviewed on 10 Jan 2026

Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
Union Square
Price was €671, price is now €503 per person
€503
per person
13 Feb - 17 Feb
found 17 hours ago
Return flight included
Philadelphia (PHL) to San Francisco (SFO)
8.8/10 Excellent! (2,792 reviews)
Great location, room was clean and staff was helpful.

Reviewed on 11 Jan 2026

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Ingold - Milldale
Price was €619, price is now €467 per person
€467
per person
13 Feb - 17 Feb
found 17 hours ago
Return flight included
Philadelphia (PHL) to San Francisco (SFO)
9/10 Wonderful! (4,699 reviews)
I actually checked out early and was able to get a partial refund. It took a few calls, but the manager was able to process the partial refund which was better than nothing based on my situation. I appreciated the staff, they were nothing but polite.

Reviewed on 10 Jan 2026

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Union Square which includes a skyscraper and a city

Union Square

4/5(287 area reviews)

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

Find hotels in Union Square

Top hotels in Mission District

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €159 per night from 23 Jan to 24 Jan
€159
23 Jan - 24 Jan
includes taxes & fees
8.8/10 Excellent! (7,258 reviews)
Nice location, GREAT breakfast, friendly staff, comfortable room

Reviewed on 10 Jan 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €132 per night from 18 Jan to 19 Jan
€132
18 Jan - 19 Jan
includes taxes & fees
8.6/10 Excellent! (2,257 reviews)
Clean room, good price, it was walkable to get food

Reviewed on 9 Jan 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €128 per night from 25 Jan to 26 Jan
€128
25 Jan - 26 Jan
includes taxes & fees
8.8/10 Excellent! (5,111 reviews)
The hotel here was very lovely and 26th floor had such a beautiful city view. Clean room, kind staff, and great amenities here. The only thing they do not have is a microwave in the room, but there is a restaurant on site and a mini cafe. Along with that, great restaurants around walking distance ...

Reviewed on 5 Jan 2026

Holiday Inn Golden Gateway by IHG
See all 4,948 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission District holiday package cost?
Our Mission District packages, which begin at just €463, are an awesome way to save big. Pick your favourite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District holiday package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your holiday your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those holiday dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cosy Dolores Park Condo By Redawning. Both will make you feel at home and are favourites among lots of travellers.
How far in advance should I book my Mission District holiday?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District holiday deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including holiday rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia holiday package?
With a holiday package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District holiday package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District holiday package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Popular places to visit

Mission Dolores Park

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Balmy Alley

Balmy Alley

Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the acclaimed art galleries and fascinating museums in this vibrant area.

Balmy Alley
Mission San Francisco de Asís

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area.

Mission San Francisco de Asís

Things to do

Alcatraz Ticket with Roundtrip Ferry & Hop-On Hop-Off

Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour

€82
per adult
88% of travellers recommend
Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

€42
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

€118
per adult
96% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.