Mission District Holidays

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Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Union Square which includes a skyscraper and a city

Union Square

4/5(287 area reviews)

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

Find hotels in Union Square

Top hotels in Mission District

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is €126 per night from 1 Mar to 2 Mar
€126
1 Mar - 2 Mar
includes taxes & fees
9/10 Wonderful! (5,342 reviews)
Helpful staff, amenities, and overall great vibes

Reviewed on 27 Feb 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €176 per night from 3 Mar to 4 Mar
€176
3 Mar - 4 Mar
includes taxes & fees
9/10 Wonderful! (7,323 reviews)
Save environment, save water, the water flow in sink made me exhausted, this is waste time instead of waste water.

Reviewed on 28 Feb 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is €156 per night from 29 Mar to 30 Mar
€156
29 Mar - 30 Mar
includes taxes & fees
8.8/10 Excellent! (2,876 reviews)
Room was nice and clean, the staff are amazing, especially to Shiley she was the best 👍

Reviewed on 27 Feb 2026

Handlery Union Square Hotel
See all 4,947 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission District holiday package cost?
Our Mission District packages, which begin at just , are an awesome way to save big. Pick your favourite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District holiday package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your holiday your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those holiday dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cosy Dolores Park Condo By Redawning. Both will make you feel at home and are favourites among lots of travellers.
How far in advance should I book my Mission District holiday?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District holiday deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including holiday rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia holiday package?
With a holiday package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District holiday package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District holiday package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Popular places to visit

Mission Dolores Park showing picnicing and a park as well as a small group of people

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Balmy Alley which includes outdoor art

Balmy Alley

Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Balmy Alley
Mission San Francisco de Asís was founded 29 June 1776 by Padre Francisco Palóu and Padre Pedro Benito Cambón. The mission is named for Saint Francis of Assisi. The current site was picked in 1782 because of the harsh conditions at the original mission. It is considered to be the oldest intact building in San Francisco. The Mission is located in the San Francisco Mission District at the corner of 16th and Dolores Streets. #Details #golden #troveontuesday #Trovember

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area.

Mission San Francisco de Asís

Things to do

Golden Gate Bay Cruise Service: sail around Alcatraz!

Golden Gate Bay Cruise - Sail Around Alcatraz! (1-hour)

€32
per adult
96% of travellers recommend
Golden Gate Bay Cruise - Sail Around Alcatraz! (1-hour)
Alcatraz Ticket with Roundtrip Ferry & Hop-On Hop-Off

Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour

€101
per adult
88% of travellers recommend
Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

€41
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.