Northeast Missouri
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
21C Museum Hotel St Louis
The cafe that sold breakfast ran out of healthy options each morning (yogurt parfait cup/ overnight oats & quinoa $8 each) They had other plates, egg with meat, etc that looked nice fwiw. Cute gift shop in the cafe. Fashionable hotel with no real 'front desk' just a checkin counter, but volunteers ...
Reviewed on 14 Jan 2026
Pear Tree Inn St. Louis Airport
Nice
Reviewed on 17 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Everything was perfect! Will stay again for sure.
Reviewed on 15 Jan 2026
White House at Grand Central
Great place
Reviewed on 27 Dec 2025
Entire 4BR Home near Lafayette Square
The home met expectations and then some. Loved the seperate area downstairs and the great backyard. The directions were clear and home located close to great attractions. The extras in the home were great. We will definely be back.
Reviewed on 2 Jan 2026
The St. Charles Guest House, lovely historic home, fun for families and groups
The house was incredible! Clean, cozy yet spacious and a perfect location 1/2 block from the historic district. Shops, eating and walking paths all just a few steps from our doorstep!
Reviewed on 18 Nov 2025
Check Northeast Missouri hotel availability
Popular places to visit
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Things to do
Tom's Town Distillery Tour and Tasting
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Kansas City Scavenger Hunt: Fountains, Fun & Hidden Finds
Kansas City Self-Guided Walking Audio Tour
Kansas City Downtown Smartphone Guided Audio Walking Tour
Explore a world of travel with Expedia
- 4 Star Hotels in Hannibal
- Benton City Hotels
- Brookfield Hotels
- Clarence Hotels
- Downing Hotels
- Ethel Hotels
- Gibbs Hotels
- Hallsville Hotels
- Hilton Hotels in Hannibal
- Hannibal Hotels
- Hotels with Bar in Kirksville
- Kirksville Hotels
- Lentner Hotels
- Macon Hotels
- Marceline Hotels
- Maywood Hotels
- Apartments in Moberly
- Moberly Hotels
- New London Hotels
- Palmyra Hotels
- Hotels with Spa in Perry
- Perry Hotels
- Rutledge Hotels
- Saverton Hotels
- Taylor Hotels
- Vandalia Hotels
- Worthington Hotels
