A waterfront promenade at sunset with a row of buildings and a railing along the path.

Ortygia Hotel Guide - Business Hotels in Ortygia, Sicily

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Ortygia Business Hotels

Tonight
13 Sept - 14 Sept
Tomorrow
14 Sept - 15 Sept
Next weekend
18 Sept - 20 Sept
In two weeks
25 Sept - 27 Sept

Our top choices for Ortygia business-friendly hotels

1. Dimore delle Zagare Ortigia

Dimore delle Zagare Ortigia
Ortigia
United States
Holly
€140
includes taxes & fees
28 Sept - 29 Sept
Dimore delle Zagare Ortigia

2. Domus Mariae Albergo

Domus Mariae Albergo
Ortigia
United States
Marino
€105
includes taxes & fees
15 Sept - 16 Sept
Domus Mariae Albergo

3. L'Approdo delle Sirene

L'Approdo delle Sirene
Ortigia
United States
Jennifer
€112
includes taxes & fees
22 Sept - 23 Sept
L'Approdo delle Sirene

4. CinqueSuites Ortigia

CinqueSuites Ortigia
Ortigia
United States
MARGARET
€162
includes taxes & fees
5 Oct - 6 Oct
CinqueSuites Ortigia

5. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
United Kingdom
Rachael
€331
includes taxes & fees
15 Sept - 16 Sept
Algila' Ortigia Charme Hotel

6. Hotel Posta

Hotel Posta
Ortigia
United States
Steven
€154
includes taxes & fees
15 Sept - 16 Sept
Hotel Posta

7. Domus Mariae Benessere

Domus Mariae Benessere
Ortigia
United States
Jun
€161
includes taxes & fees
22 Sept - 23 Sept
Domus Mariae Benessere

8. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
United States
NINA
€352
includes taxes & fees
7 Oct - 8 Oct
Grand Hotel Ortigia Siracusa

9. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
Australia
Leanne
€691
includes taxes & fees
17 Sept - 18 Sept
Grand Hotel Des Ètrangers - The Leading Hotels of the World

10. Hotel Gutkowski

Hotel Gutkowski
Ortigia
Canada
MARK
Hotel Gutkowski
View all properties

Top Ortygia Hotel Reviews

Domus Mariae Albergo

Domus Mariae Albergo

10/10 Excellent
"Perfect staff perfect location hotel very clean"
Marino 4-night trip
Posted 18 hours ago
Domus Mariae Albergo
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

8/10 Good
"This hotel is well situated in Ortigia and is in a lovely old building. We enjoyed the staff, the bar and the breakfast. However we were misled by our room booking on Expedia. We expect d a room with a view of a mediterranean garden. We got a room facing an inner area- the light well - which afforded very little natural light in the room.band faced another bedroom’s window. The room was very small, with the shower in a closet area, and the toilet in a room on the other side of the bedroom. We asked to move but there was nothing available or offered for the two nights we stayed. All for $480/night. I expected more and would recommend that you book this hotel with caution if you value nice accommodation."
Anne 2-night trip
Posted 2 days ago
Algila' Ortigia Charme Hotel
Charme Hotel Henry's House

Charme Hotel Henry's House

10/10 Excellent
"Really cute boutique hotel with a lot of charm and character. Cozy, welcoming, and in a super convenient location right in Ortigia. We really enjoyed our stay!"
Ton-Duc David 2-night trip
Posted 3 days ago
Charme Hotel Henry's House
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Clean room , service , staff , shops near , big room"
Louis-Philippe 2-night trip
Posted 4 days ago
Palazzo Artemide - VRetreats, SLH Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Old world Italian charm and great service. Would have preferred something more centrally located with a pool and better breakfast."
Karen 3-night trip
Posted 2 weeks ago
Grand Hotel Ortigia Siracusa
Alla Giudecca

Alla Giudecca

10/10 Excellent
"The hotel is in a great location with everything in walking distance. The late check in was easy with our instructions posted on the door and a phone number to call first. We used WhatsApp. The room was clean and the size of a small apartment. The staff was pleasant and helpful. The parking garage was a three minute walk from the hotel. We would stay here again."
Heidi 7-night trip
Posted 2 months ago
Alla Giudecca
Hotel Posta

Hotel Posta

10/10 Excellent
"Excelente ubicación además de una vista hermosa! Las personas muy amables y agradables."
Aydee 1-night trip
Posted 2 months ago
Hotel Posta

Explore a world of travel with Expedia