Panacea Hotels from €93 - Fully Refundable Options

A calm lake with a wooden pier extending into the water, surrounded by tall grasses.

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Waterpark

Villa

Hot tub

Family friendly

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Our top choices for Panacea hotels

A pink door with a window, set in a corrugated metal exterior with wooden trim.

A wooden bench in a natural setting with trees and a body of water in the background.

A kitchen with a wooden countertop, a built-in sink, and a trash can.

A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a sink. There are wooden shelves above the counter and a window with a view.

1. The Panacea Motel

Panacea

Dashawn

€118

includes taxes & fees

15 Nov - 16 Nov

A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.

A modern hotel lobby with a sofa, armchairs, a desk, and a TV.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel lobby with a coffee bar, seating area, and a clock on the wall.

2. Best Western Wakulla Inn & Suites

Crawfordville

James

€107

includes taxes & fees

15 Nov - 16 Nov

A spacious indoor area with tiled flooring, multiple tables and chairs, a stone fireplace, and a glass door entrance.

A hotel with a red facade, a covered entrance, and palm trees.

A hotel room with a bed, a desk, a chair, a small table with a vase, a trash bin, and a wooden door.

3. Wildwood Inn

Crawfordville

Shane

€119

includes taxes & fees

5 Nov - 6 Nov

A spacious lobby with leather sofas, a coffee table, and a large window with arched frames.

A boat docked at a pier with passengers on board.

A courtyard with a central fountain, surrounded by well-maintained hedges and trees.

A spacious lobby with high ceilings, ornate ceiling decorations, and large windows.

4. The Lodge at Wakulla Springs

Crawfordville

Joy

€112

includes taxes & fees

9 Nov - 10 Nov

A bar area with a long counter, stools, and a variety of bottles and glasses.

A resort with multiple tennis courts, a swimming pool, and a golf course.

A swimming pool with lounge chairs, palm trees, and a clear blue sky.

A living room with a sofa set, a television, and a ceiling fan.

5. St James Bay Golf & Pickleball Resort

Carrabelle

Richard

€157

includes taxes & fees

18 Oct - 19 Oct

A marina with boats docked, a small building, and a clear sky.

A pool area with a table and chairs, a building with doors, and a palm tree.

A spacious room with a pool table, a billiards table, and a dining area with chairs and a table.

A marina with multiple docks and boats, connected by walkways, and surrounded by greenery and buildings.

6. The Moorings Hotel and Marina

Carrabelle

Tina

€136

includes taxes & fees

20 Oct - 21 Oct

A covered patio with a table and chairs, a wooden ceiling fan, and a view of the surrounding greenery.

A bedroom with a wooden four-poster bed, a ceiling fan, a bookshelf, and a wall-mounted lamp.

A yellow door with a window, a potted plant, a white wall-mounted light fixture, and a staircase with yellow curtains.

A cozy living room with a sofa, a small table, and a ceiling fan.

7. The Old Carrabelle Hotel

Carrabelle

Christy

€109

includes taxes & fees

29 Oct - 30 Oct

A hotel room with two beds, a nightstand, a lamp, and a bathroom visible through an open door.

A hotel room with a large bed, two bedside tables, a desk with a chair, and a lamp.

A bathroom with a toilet, shower, and sink with a marble countertop.

A motel with a single-story structure, a covered parking area, and a palm tree in front.

8. Franklin Inn

Carrabelle

Nathan

€93

includes taxes & fees

19 Oct - 20 Oct

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Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)

Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.

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Bald Point State Park

8.6/10 (20 reviews)

Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.

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Mashes Sand Beach

8.8/10 (3 reviews)

Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.

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Public Beach Access

Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.

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Wilson Beach

Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.

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Bayside Marina

Bayside Marina offers 35 wet slips along Ochlockonee Bay, where manatees often make surprise appearances. Boaters can secure overnight dockage while exploring nearby wildlife refuges and nature trails.

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Silver Lake

Swim in crystal-clear waters along a pristine 250-foot white sand beach surrounded by longleaf pines. The mile-long interpretive trail offers peaceful wildlife encounters with bald eagles and turtles.

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Panacea Springs

Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.

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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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A coastal resort with beachfront villas and a clear blue sky.

Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"This was our second stay for my Mom and I and of course our two fur babies!! House is super cute and the views are awesome ! Agnes was great to work with. Great place to relax and unwind "

The Best Beach-Front House “Get-A-Way” in Florida

10/10 Excellent

"Wonderful property! I was looking for a quiet, dog-friendly beach vacation rental and this was the perfect spot! Perfect for long beach walks and our dog had a blast on the beach…true water dog. Owners were very responsive and accommodating. Ate at Angelo’s and 10/10 recommend!The beach was literally in the back yard. It was so easy to just walk out back and go down to the water."

Great sunrise view from dining area and decks. Easy beach access.

10/10 Excellent

"Kevin was wonderful to deal with. The house was very, very clean. Zero complaints!"

Coastal Getaway on canal-steps to the beach

10/10 Excellent

"We always stay here everytime we go to panacea and it is always an amazing trip! My kids call it their home away from home! Can't wait to go again!"

Cozy bayfront farmhouse!

10/10 Excellent

"This is our second time staying here. Nice and clean , we enjoy back screened in porch overlooking the bay!"

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

8/10 Good

"It was a very nice stay. I would suggest including a picture of the outside as far as the stairs one must climb with luggage. We were capable but I don't think everyone would be."

Lighthouse- enjoy the water, bask in the view

10/10 Excellent

"A very remote location, laid back small community and very natural beaches."

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

10/10 Excellent

"This was our third trip to this house for a week. Enjoyed everything.. you don't need anything."

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

10/10 Excellent

"Great beach bungalow. Pictures don’t do it justice. Much more spacious than we anticipated. Had everything we needed. Very cute and wonderful views of the beach. Area was great for us, quiet, private, not touristy at all. We saw so many stars at night, even saw the Milky Way the first night there. Definitely recommend if you are looking for that old school small Florida beach house vibe."

More cheap stays in Panacea

Franklin Inn

1589 US-98 Carrabelle FL

€93

19 Oct - 20 Oct

includes taxes & fees

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL

€107

15 Nov - 16 Nov

includes taxes & fees

8.8/10 Excellent! (1,001 reviews)

The Old Carrabelle Hotel

201 Tallahassee St Carrabelle FL

€109

29 Oct - 30 Oct

includes taxes & fees

9.6/10 Exceptional! (51 reviews)

The Panacea Motel

1545 Coastal Hwy Panacea FL

€118

15 Nov - 16 Nov

includes taxes & fees

The Moorings Hotel and Marina

1000 Hwy 98 Carrabelle FL

€136

20 Oct - 21 Oct

includes taxes & fees

8.6/10 Excellent! (54 reviews)

Cozy Waterfront 'island House' on Live Oak Island!

Crawfordville FL

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Frequently asked questions

Where is the best place to stay in Panacea?

Based on Expedia's traveller preferences, The Panacea Motel is a top place to stay in Panacea. Other good choices for your trip include Your Fall Escape: FSU Football & Scalloping and Lighthouse- enjoy the water, bask in the view. See all available top hotels, or vacation rentals in Panacea.

What are some of the best holiday rentals that Panacea has to offer?

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.: This highly rated holiday home rental in Panacea is located on the beach, and has an outdoor pool, a balcony and air conditioning to put you at ease in your new surroundings. It has 6 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. Other favourite homes for rent in Panacea are Your Fall Escape: FSU Football & Scalloping and Coastal Getaway on canal-steps to the beach. See all vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

What's the best dog-friendly place to stay in Panacea?

The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

What are some accommodation options with pools in Panacea?

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless Internet access, a pool and kitchens. Another choice with an on-site pool is BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.. View all hotels with pools in Panacea.

How is it to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 228 hotels and other accommodation options to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach and Bald Point State Park. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Wilson Beach and Public Beach Access. Take a look at what more there is to see and do in Expedia's Panacea guide.

What's the seasonal weather in Panacea?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.

Panacea Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Panacea

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Panacea hotels

1. The Panacea Motel

2. Best Western Wakulla Inn & Suites

3. Wildwood Inn

4. The Lodge at Wakulla Springs

5. St James Bay Golf & Pickleball Resort

6. The Moorings Hotel and Marina

7. The Old Carrabelle Hotel

8. Franklin Inn

Stay near popular Panacea attractions

Alligator Point Beach

Bald Point State Park

Mashes Sand Beach

Public Beach Access

Wilson Beach

Bayside Marina

Silver Lake

Panacea Springs

Learn more about Panacea

Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

The Best Beach-Front House “Get-A-Way” in Florida

Great sunrise view from dining area and decks. Easy beach access.

Coastal Getaway on canal-steps to the beach

Cozy bayfront farmhouse!

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Lighthouse- enjoy the water, bask in the view

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

More cheap stays in Panacea

Franklin Inn

Best Western Wakulla Inn & Suites

The Old Carrabelle Hotel

The Panacea Motel

The Moorings Hotel and Marina

Cozy Waterfront 'island House' on Live Oak Island!

Frequently asked questions

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