Holiday Rentals in Panacea

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Holiday Rentals in Panacea

Beach
Old Florida Beach Bungalow
10.0 out of 10, Exceptional, (218)
"Very quaint. Perfect location. Quiet. Clean. Definitely would stay there again."
Old Florida Beach Bungalow
On the beach, sun-loungers, beach towels
Hideaway Beach Cottage on waterfront with amazing views.
10.0 out of 10, Exceptional, (21)
"We live in NW FL and wanted a quick getaway - AWAY from it all; and we found this sweet cottage on the water. With 2 dogs, pet friendly is the only way we go and the owner had a lot of items to use for free for pets, the beach, games, etc... Well appointed and incredibly hospitable and accommodating even though I messed up the reservation and was a day off. The house was clean with nice additions (soft close trash), wall lights for the floor, outdoor chairs and cushions, kitchen stocked with...
Hideaway Beach Cottage on waterfront with amazing views.
Living area
Marsh Beauty
10.0 out of 10, Exceptional, (31)
"This was just an amazing little place! It was exactly what I had hoped it would be! It was so quiet and peaceful and was a much needed rest for the soul! I can't wait to visit again!"
Marsh Beauty
Save an average of 15% on thousands of hotels when you're signed in
On the beach, sun-loungers
🏖️Beachfront🏖️ Forget your worries in this spacious and serene space ♡
10.0 out of 10, Exceptional, (11)
"Our family enjoyed a relaxing and fun wknd at this beautiful beach house. There was plenty of room for everyone with the amenities of home. It allowed for our family to celebrate the joyous occasion of a college graduation together! Highly recommended!"
🏖️Beachfront🏖️ Forget your worries in this spacious and serene space ♡
Fridge, microwave, stovetop, dishwasher
Waterfront Home: Spectacular On-Site Fishing!
10.0 out of 10, Exceptional, (14)
"Stayed here while fishing a tournament in Panacea. Great location. House had everything we needed."
Waterfront Home: Spectacular On-Site Fishing!
Interior
Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views
9.2 out of 10, Wonderful, (15)
"We enjoyed our stay very much. My wife and are seniors, and it was ground floor living. Very hard to find on the water. The home had a couple hiccups, the owner is handle them right away. Great commutation. Would definitely stay again. JIM & Wyndi.."
Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views
Fridge, microwave, oven, stovetop
PRIVATE LUXURY BEACHFRONT HOME! - LAST MINUTE APRIL/MAY DISCOUNT!
10.0 out of 10, Exceptional, (77)
"This beach house has everything we needed for one of our best beach trips yet!! We had 11 people ranging from ages 1-62. There was plenty of room for all of us! Each family had their own area. Private, yet all together! We had people fishing, kayaking, swimming, shelling, grilling, crabbing and just chilling in the beach. The listing is exactly as shown. We have already requested to book next year!"
PRIVATE LUXURY BEACHFRONT HOME! - LAST MINUTE APRIL/MAY DISCOUNT!
Property grounds
Best deal at Alligator Point
9.6 out of 10, Exceptional, (95)
"If you want a place to stay close to several beaches, but do not want to be in the middle of everything, this is your place. Pet friendly is a big plus with a fenced in front yard and mostly fenced in back yard. My family enjoyed our stay here."
Best deal at Alligator Point
CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom
9.4 out of 10, Exceptional, (77)
"Very nice accommodations, kitchen had everything you need to cook a meal, large front and rear porch. Located across from pool and tennis court which was very convenient. Would definitely stay again."
CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom
On the beach, sun-loungers
BEACHFRONT! Memorial Week Cancellation! Million Dollar view from EVERY Room!
9.4 out of 10, Exceptional, (116)
"The property was beautiful. There was alot of wildlife present which was pretty cool. There are alot of houses around but we still had our own place on the beach. Great house for a beach vacation."
BEACHFRONT! Memorial Week Cancellation! Million Dollar view from EVERY Room!
Terrace/patio
Connie's Cottage- "The Hemingway" - Vintage Chic
10.0 out of 10, Exceptional, (27)
"Connie has left no stone unturned when it comes to stocking her cottage with everything you need. She graciously left us snacks which was greatly appreciated since we arrived late and we're tired so a snack and bed was perfect. Love love the tv room. Every room is decorated so charming. We will be staying again for sure. Again Thank You Connie for being such a gracious host. Harley and Patsy"
Connie's Cottage- "The Hemingway" - Vintage Chic
Property grounds
Breezy Home w/ Grills, Pool & Beach Access!
10.0 out of 10, Exceptional, (13)
"The cleanest and most well kept property we have stayed at. Love the location. Love the house. I have already recommended to friends."
Breezy Home w/ Grills, Pool & Beach Access!
Outdoor dining
Cottage on the Bay
9.4 out of 10, Exceptional, (11)
"Big open common area with Kitchen/living room, with plenty if room to eat, play ganes, have a movie night with three big bedrooms with awesome queen mattresses, we slept well! The 4th bedroom has two twin beds which was great for the bigger kids and the sleeper couch in the sunroom was great for the smaller kids. We enjoyed using the kayaks, fishing, exploring nature, finding hermit crabs, sand castles, etc...we also went to the Aquarium nearby, Alligator Point to fish for baby sharks and swim,...
Cottage on the Bay
On the beach, sun-loungers, beach towels
Paradise Found ~ Direct Beachfront Florida Oasis
10.0 out of 10, Exceptional, (24)
"The dog friendly beach was nearly deserted. The people we came across were friendly, and loved watching our dogs play in the surf. Our accommodations were comfortable, equipped with everything we needed, and directly on the beach. We will definitely return for another fun adventure."
Paradise Found ~ Direct Beachfront Florida Oasis
Pool
Coastal Getaway on canal-steps to the beach
10.0 out of 10, Exceptional, (29)
"Loved the house."
Coastal Getaway on canal-steps to the beach
Beach
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
10.0 out of 10, Exceptional, (108)
"My family stayed at this beautiful house for my son’s graduation from FSU. It was absolutely perfect for all of us. I have never rented a home that had a kitchen stocked as well as this one. Everything you could want was there for cooking. They even have the little things like tin foil, all the spices, sharp knives, coffee filters, and extra paper towels if needed. I could go on and on. We also all felt such a sense of peacefulness while there. The views from every room of the gulf and also the...
The price is €1,803
per night
24 May - 25 May
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
On the beach, sun-loungers, beach towels
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
10.0 out of 10, Exceptional, (45)
"The beach house is well appointed and maintained. Everything one would need for a stay is already there (minus the food, of course). The rooms were just as shown in the pictures, clean and well organized. We enjoyed fishing off the beach; although no one swam in the water due to the murky color. In the evening we enjoyed walking on beach as the tide went out. Overall, it was a lovely time."
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
Property grounds
Sitting right on the beach! THE SAND CASTLE
10.0 out of 10, Exceptional, (178)
"This is a home that is perfection in every detail - even the ones you cannot begin to imagine you require. Sandcastle is a gloriously luxurious, peaceful, well appointed vacation home. If you are looking for peace and serenity in the most beautiful location imaginable, this is it. I saw more pelicans than people, more dolphins than cars and more stars than I’ve ever seen in a black sky. It’s like you’re at the end of the world. The level of physical comfort was as if I was at my own home. Thank...
The price is €946
per night
16 Jun - 17 Jun
Sitting right on the beach! THE SAND CASTLE
Property grounds
Charming Alligator Point "Old Florida” Beach Cottage
10.0 out of 10, Exceptional, (140)
"Wendy was great! She went above and beyond to make our stay comfortable. It was quiet and relaxing, just what we were looking for."
Charming Alligator Point "Old Florida” Beach Cottage
Lake
Authentic log Cabin By the Bay.
10.0 out of 10, Exceptional, (11)
"We enjoyed a memorable experience! The host Debbie was incredible in terms of attentiveness, flexibility and overall hospitality! As tournament anglers, we arrived at the property to find a pole barn style parking location for all 4 of our boats with power and water. The log cabin has a great full kitchen with an awesome bar filled with seating and an awesome den and dining room. The bedrooms were top notch! I highly recommend this property and this will be our Panacea "Go-To" place to stay!...
Authentic log Cabin By the Bay.
Don't see what you're looking for?
See all available properties in Panacea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Panacea you may be interested in

Comfort Cabin | Living area
The Panacea Motel
2.0 star property
9.4 out of 10, Exceptional, (20)
"Fascinating part of Florida. Updated old school hotel with all the conveniences one could want, imho. "
The price is €133
per night
27 May - 28 May
The Panacea Motel
Interior
Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views
9.2 out of 10, Wonderful, (15)
"We enjoyed our stay very much. My wife and are seniors, and it was ground floor living. Very hard to find on the water. The home had a couple hiccups, the owner is handle them right away. Great commutation. Would definitely stay again. JIM & Wyndi.."
Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views
Beach
Old Florida Beach Bungalow
10.0 out of 10, Exceptional, (218)
"Very quaint. Perfect location. Quiet. Clean. Definitely would stay there again."
Old Florida Beach Bungalow
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Panacea holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Panacea holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panacea holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panacea holiday rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in Panacea?

Yes, there are holiday rentals in Panacea close to Gulf Specimen Public Aquarum, or you can select a more secluded option if you're looking for a relaxing stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best holiday rentals that Panacea has to offer?

Old Florida Beach Bungalow: This highly rated holiday home rental in Panacea is located near the beach, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. You and your friends and family can relax into your holiday with amenities such as a selection of books. Some other homes for rent in Panacea include Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views and PRIVATE LUXURY BEACHFRONT HOME! - LAST MINUTE APRIL/MAY DISCOUNT!.

How many holiday rentals are there in Panacea?

Choose from 122 Expedia holiday rentals in Panacea for a memorable holiday.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Bayside Marina are other places worth a visit.

What’s a holiday rental in Panacea like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Panacea. Holiday rentals offer amenities such as WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a clean environment, a holiday rental can provide a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for family trips or small group gatherings.

Recent reviews of Panacea properties
Expedia verified reviews