A pier extending into calm waters with a small boat docked at the end.

Holiday Rentals in Panacea

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Our top choices for Panacea holiday rentals

1. Panacea Treehouse⭐️ Waterfront-Boat Friendly

Panacea Treehouse⭐️ Waterfront-Boat Friendly
Panacea
10.0 out of 10, Exceptional, (25 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
The price is €269
includes taxes & fees
23 Aug - 24 Aug
Panacea Treehouse⭐️ Waterfront-Boat Friendly

2. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
The price is €156
includes taxes & fees
23 Aug - 24 Aug
Cozy Panacea Retreat #3 (King)

3. romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
The price is €274
includes taxes & fees
21 Aug - 22 Aug
romantic get away for 2 right on the Ochlockonee river

4. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks
Panacea
10.0 out of 10, Exceptional, (4 reviews)
"Had a great stay! We would book here again."
United States
Ashley D.
The price is €415
includes taxes & fees
23 Aug - 24 Aug
Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

5. Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
Point & Paddle Waterfront Retreat @Alligator Point

6. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (99 reviews)
"Excellent beach front location, wonderful amenities like beach chairs, umbrellas, toys and towels made the stay easy and stress free! "
United States
Juliet H.
The price is €576
includes taxes & fees
3 Sept - 4 Sept
The Best Beach-Front House “Get-A-Way” in Florida

7. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Panacea
9.6 out of 10, Exceptional, (93 reviews)
"We were traveling with 1 small dog, a 1 year old and 8 adults for 1 daughter graduation from FSU. The host confirmed the people coming and when we got there she had a cute little doggie set up ready and a high chair for our granddaughter. The property was perfect, the view was extraordinary. We are thrilled and will be back! It was an easy 1 hour drive from FSU to the house and we were so happy with everything about it!"
United States
Stacy C.
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

8. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
The price is €156
includes taxes & fees
3 Sept - 4 Sept
Cozy Panacea Retreat #3 (King)

9. Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
The price is €181
includes taxes & fees
19 Sept - 20 Sept
Queen Kitchenette by the Bay #13

10. NEW - St. Teresa Beach Escape w/ Private Beach Acc

NEW - St. Teresa Beach Escape w/ Private Beach Acc
Lanark Village
10.0 out of 10, Exceptional, (2 reviews)
"This house was very comfortable, beds, pillows, towels, sofa, etc. Quiet, peaceful, serene setting. Close proximity to beach and the pool was an added bonus!Thank you for a very enjoyable stay!"
United States
Debra M.
The price is €694
includes taxes & fees
21 Aug - 22 Aug
NEW - St. Teresa Beach Escape w/ Private Beach Acc

11. Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
The price is €181
includes taxes & fees
19 Sept - 20 Sept
Cozy Panacea Retreat #7 (King)

12. Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
The price is €181
includes taxes & fees
19 Sept - 20 Sept
Perfect Panacea 1 Bedroom Apt, #2

13. Queen Kitchenette by the Bay #8

Queen Kitchenette by the Bay #8
Panacea
The price is €194
includes taxes & fees
3 Sept - 4 Sept
Queen Kitchenette by the Bay #8

14. Panacea Cozy Retreat #6 (DQ)

Panacea Cozy Retreat #6 (DQ)
Panacea
The price is €195
includes taxes & fees
3 Sept - 4 Sept
Panacea Cozy Retreat #6 (DQ)

15. Panacea Cozy Retreat #4 (DQ)

Panacea Cozy Retreat #4 (DQ)
Panacea
The price is €195
includes taxes & fees
3 Sept - 4 Sept
Panacea Cozy Retreat #4 (DQ)

16. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point
10.0 out of 10, Exceptional, (131 reviews)
"Beautiful house with awesome views of the gulf and the bay from all rooms. Fenced in yard was perfect for our dog. Location is very relaxing. I can't wait to go back."
United States
V G.
The price is €1,912
includes taxes & fees
3 Sept - 4 Sept
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

17. Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf

Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf
Crawfordville
10.0 out of 10, Exceptional, (81 reviews)
"What a great property! The house is fully equipped for your stay and the sunrises are breathtaking!"
United States
Donna M.
The price is €268
includes taxes & fees
23 Aug - 24 Aug
Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf

18. Enjoy Crawfordville at the Courtyard’s Pelican Cottage.

Enjoy Crawfordville at the Courtyard’s Pelican Cottage.
Crawfordville
10.0 out of 10, Exceptional, (138 reviews)
"Super cute cottage, roomy and equipped with everything you would need for your stay. I enjoyed a cup of hot tea on the front porch on the day it rained. Lots of great restaurants nearby. Owner was very helpful and answered our questions right away. Hope to come back soon!"
United States
Jennifer W.
The price is €196
includes taxes & fees
20 Sept - 21 Sept
Enjoy Crawfordville at the Courtyard’s Pelican Cottage.

19. Enjoy Crawfordville at the Courtyard’s Oyster Cottage

Enjoy Crawfordville at the Courtyard’s Oyster Cottage
Crawfordville
10.0 out of 10, Exceptional, (69 reviews)
"Wonderful stay, everything clean and comfortable."
United States
Robert G.
The price is €202
includes taxes & fees
2 Sept - 3 Sept
Enjoy Crawfordville at the Courtyard’s Oyster Cottage

20. Dragonfly on the Canal Golf cart included!

Dragonfly on the Canal Golf cart included!
Crawfordville
10.0 out of 10, Exceptional, (54 reviews)
"Was a great spacious place. We stayed for graduation weekend and could not have been happier. The porch is amazing!"
United States
Kristy B.
Dragonfly on the Canal Golf cart included!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panacea Hotel Reviews

Find out more about Panacea

Everything you need to know about Panacea holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Panacea holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panacea holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panacea holiday rentals we have selected for you start as low as €269 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

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Frequently asked questions

Can I find holiday rentals in Panacea?

Yes, there are holiday rentals in Panacea close to Gulf Specimen Public Aquarum, or you can select a more secluded option if you're looking for a relaxing stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best holiday rentals that Panacea has to offer?

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations: This highly rated holiday home rental in Panacea is located on the beach, and has a patio, a BBQ and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Another good choice for your trip to Panacea is Best deal at Alligator Point.

How many holiday rentals are there in Panacea?

Choose from 179 Expedia holiday rentals in Panacea for a memorable holiday.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a holiday rental in Panacea like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Panacea. Holiday rentals offer amenities such as WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a clean environment, a holiday rental can provide a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for family trips or small group gatherings.