Panama City Hotel Guide. Hotels in San Francisco, Panama City, Panama

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13 Nov - 14 Nov
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Our top choices for San Francisco hotels

A balcony with wicker chairs and a view of the cityscape.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,435 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is €118
includes taxes & fees
16 Nov - 17 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A covered outdoor seating area with a view of a city skyline and water.

2. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,245 reviews)
"We loved our stay, staff was very helpful, the hotel is very well located, and the breakfast is to die for!"
United States
CLAUDIA
The price is €96
includes taxes & fees
21 Nov - 22 Nov
Plaza Paitilla Inn Hotel
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.

3. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location"
United States
Yisbel
The price is €130
includes taxes & fees
28 Nov - 29 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

4. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (238 reviews)
"very nice place to stay"
United States
purabi
The price is €166
includes taxes & fees
30 Nov - 1 Dec
Boutique Apartments Panamá Coco del Mar
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

5. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"It was a great stay! I would stay here again!"
United States
Brittney
The price is €129
includes taxes & fees
21 Nov - 22 Nov
Aloft by Marriott Panama
A rooftop pool area with lounge chairs, a large umbrella, and a city skyline view.

6. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is €151
includes taxes & fees
17 Nov - 18 Nov
The Hub by Boutique Apartments
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and modern buildings.

7. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.8 out of 10, Excellent, (42 reviews)
"The hotel staff was responsive and helpful after I realized I had left clothing behind in the closet. They kept this in reserve until it was able to be retrieved. Breakfast was good, pool was nice. Recommended to stay here- good amount of space and modern design."
United States
Patrick
The price is €130
includes taxes & fees
14 Nov - 15 Nov
Dovle Residences by HMS-Preferred Member
A rooftop pool area with modern lounge chairs, a glass railing, and a view of high-rise buildings.

8. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
6.8 out of 10, (3 reviews)
"Perfect"
United States
Lorenz
The price is €172
includes taxes & fees
18 Nov - 19 Nov
Living 73 Panamá by Boutique Apartments
Lobby sitting area

9. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (68 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is €139
includes taxes & fees
20 Nov - 21 Nov
San Francisco by Wynwood House
A rooftop pool with lounge chairs, offering a city view.

10. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (50 reviews)
"Thanks for your hospitality I left everything clean"
United States
Loira
The price is €143
includes taxes & fees
15 Nov - 16 Nov
Boutique Apartments Atlapa
A rooftop swimming pool with a city skyline view, surrounded by modern buildings.

11. Loom by Boutique Apartments

Loom by Boutique Apartments
3.0 star property
San Francisco
The price is €170
includes taxes & fees
14 Nov - 15 Nov
Loom by Boutique Apartments
A modern building with a glass facade and a curved metallic structure.

12. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,743 reviews)
"We always stay there and have a good experience, good breakfast and very nice staff"
United States
Wladimir
The price is €108
includes taxes & fees
14 Dec - 15 Dec
Decapolis Hotel Panama City
A hotel room with a large bed, a sofa, a dresser, and a view of palm trees and a bridge.

13. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (16 reviews)
"Very well located and cheap and convenient"
United States
SANTIAGO
The price is €60
includes taxes & fees
16 Nov - 17 Nov
Casa Orquídea
A swimming pool with lounge chairs and palm trees, surrounded by modern buildings.

14. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff was helpful"
United States
Jheanell
The price is €192
includes taxes & fees
20 Nov - 21 Nov
Sheraton Grand Panama
A modern living room with a sofa, dining table, chairs, and a city view.

15. Corporate Stays - Loom - 201

Corporate Stays - Loom - 201
2.0 star property
San Francisco
The price is €179
includes taxes & fees
16 Nov - 17 Nov
Corporate Stays - Loom - 201
A modern hotel pool area with a clear blue pool, white lounge chairs, and a cityscape view in the background.

16. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (4 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is €243
includes taxes & fees
16 Nov - 17 Nov
Wanders Panama by Boutique Apartments
A high-rise hotel with a modern glass facade, surrounded by a dense urban skyline.

17. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,878 reviews)
"Loved our stay there"
United States
Amanda
The price is €149
includes taxes & fees
20 Nov - 21 Nov
Megapolis Hotel Panamá
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

18. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,146 reviews)
"Breakfast was great, friendly staff, clean rooms."
United States
Everlyn
The price is €149
includes taxes & fees
22 Nov - 23 Nov
Las Americas Golden Tower Panama
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

19. Pty Loft-style 1br Cincuentenario Bay

Pty Loft-style 1br Cincuentenario Bay
2.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"Buenisimo todo"
Mexico
Germain
The price is €143
includes taxes & fees
17 Nov - 18 Nov
Pty Loft-style 1br Cincuentenario Bay
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

20. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (697 reviews)
"Great place!"
United States
david
The price is €205
includes taxes & fees
12 Dec - 13 Dec
Residence Inn by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A balcony with wicker chairs and a view of the cityscape.
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,435 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,245 reviews
View
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,002 reviews
View
Lobby sitting area
San Francisco by Wynwood House
3.0 star property
9.2
Wonderful
68 reviews
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,000 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Frequently Asked Questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Ramada Plaza by Wyndham Panama Punta Pacifica and Decapolis Hotel Panama City.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 323 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Pacific Center are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Bingo 90, Soho City Center and National Shrine of the Heart of Mary. When you're sightseeing in Panama City, Panama Viejo Museum and Multicentro Panama are also worth a stop.