San Francisco hotels, Panama City, Panama: Panama City Hotel Guide

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Property	Property class	Guest rating
Ramada Plaza by Wyndham Panama Punta Pacifica	4.0 star property	9.6 Exceptional 1,309 reviews	View
Aloft by Marriott Panama	3.5 star property	8.8 Excellent 1,000 reviews	View
Courtyard by Marriott Panama Multiplaza Mall	4.0 star property	9.0 Wonderful 1,006 reviews	View
Plaza Paitilla Inn Hotel	3.5 star property	9.4 Exceptional 2,224 reviews	View
Decapolis Hotel Panama City	4.0 star property	8.6 Excellent 1,713 reviews	View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

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A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

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A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

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Top San Francisco Hotel Reviews

Central Hotel Panama Casco Viejo

10/10 Excellent

"I recomend this Property. Is beautiful and amazing."

Residence Inn by Marriott Panama City

10/10 Excellent

"A wonderful stay and truly memorable experience I had a wonderful stay at Residence Inn during my solo birthday trip. The hotel is beautiful, clean, peaceful, and in a very convenient location, with easy access to the shopping mall and nearby attractions. My room had an absolutely beautiful view of the Pacific, and waking up to that view gave me such a feeling of peace and happiness every day. I especially want to recognize the Front Desk team for their kindness, professionalism, and willingness to help. They assisted me with a room issue and also supported me when I had a problem with a tour arranged through the hotel. They were always attentive and made me feel genuinely cared for. The hotel itself was excellent: very clean rooms and common areas, a lovely pool, delicious breakfasts, and a peaceful atmosphere. I also truly appreciated the thoughtful welcome and apology details after the room inconvenience, as well as the beautiful birthday surprise they prepared for me. Those gestures made my stay feel very personal and special. I traveled alone, and the warmth and kindness of the staff made me feel comfortable and welcome throughout my stay. I left Panama with wonderful memories and, honestly, I would love to come back. I still remember the feeling of arriving at the hotel, looking out the window at the beautiful Pacific and feeling so happy and at peace. Thank you to the entire team for being part of such a beautiful trip. I highly recommend this hotel!"

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Aloft by Marriott Panama and Courtyard by Marriott Panama Multiplaza Mall.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 325 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Pacific Center. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.

Panama City Hotel Guide. Hotels in San Francisco, Panama City, Panama

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Our top choices for San Francisco hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

2. Courtyard by Marriott Panama Multiplaza Mall

3. Aloft by Marriott Panama

4. Modern Apartments PH Living 73 SF

5. Sheraton Grand Panama

6. Boutique Apartments Panamá Coco del Mar

7. Boutique Apartments Atlapa

8. Decapolis Hotel Panama City

9. Dovle Residences by HMS-Preferred Member

10. Plaza Paitilla Inn Hotel

11. San Francisco by Wynwood House

12. The Hub by Boutique Apartments

13. Las Americas Golden Tower Panama

14. JW Marriott Panama

15. Casa Orquídea

16. Megapolis Hotel Panamá

17. Wanders Panama by Boutique Apartments

18. Residence Inn by Marriott Panama City

19. Cozy Urban Loft 1br Near Coast

20. Living 73 Panamá by Boutique Apartments

Compare popular hotels in San Francisco

Where to stay in San Francisco

Casco Viejo

Bella Vista

El Cangrejo

Punta Paitilla

San Felipe

Top San Francisco Hotel Reviews

Central Hotel Panama Casco Viejo

Frequently asked questions