A bridge over a body of water with several boats.

Panama City Hotel Guide. Hotels in San Francisco, Panama City, Panama

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Check prices for these dates

This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

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Our top choices for San Francisco hotels

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

1. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,014 reviews)
"It was a great stay"
United States
Shaniyah
The price is €128
includes taxes & fees
9 Oct - 10 Oct
Aloft by Marriott Panama
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

2. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is €175
includes taxes & fees
30 Sept - 1 Oct
Living 73 Panamá by Boutique Apartments
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

3. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,009 reviews)
"I had an enjoyable stay, can’t wait t return."
United States
Holly
The price is €118
includes taxes & fees
17 Oct - 18 Oct
Courtyard by Marriott Panama Multiplaza Mall
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

4. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (234 reviews)
"very nice place to stay"
United States
purabi
The price is €169
includes taxes & fees
1 Oct - 2 Oct
Boutique Apartments Panamá Coco del Mar
A buffet with various food items and a decorative plant.

5. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,002 reviews)
"Great facility and great location."
United States
Noel
The price is €178
includes taxes & fees
9 Oct - 10 Oct
Sheraton Grand Panama
Balcony

6. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (63 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is €125
includes taxes & fees
1 Oct - 2 Oct
San Francisco by Wynwood House
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

7. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,764 reviews)
"Hotel was amazing"
United States
Sheena
The price is €140
includes taxes & fees
30 Sept - 1 Oct
Megapolis Hotel Panamá
A modern building with a glass facade, a curved structure, and a flat roof.

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,727 reviews)
"Location is wonderful."
United States
Jorge Luis
The price is €98
includes taxes & fees
12 Oct - 13 Oct
Decapolis Hotel Panama City
A poolside area with lounge chairs and a view of the ocean.

9. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,002 reviews)
"Great experience in great hotel You can’t be wrong if you book room with them, I will be back again for sure"
United States
Nemanja
The price is €246
includes taxes & fees
17 Oct - 18 Oct
JW Marriott Panama
A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

10. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (15 reviews)
"Really great location, very kind and helpful staff. Some things may need some updating, but i would not think twice before booking the place!"
United States
Brett
The price is €56
includes taxes & fees
5 Oct - 6 Oct
Casa Orquídea
A covered outdoor seating area with a view of a city skyline and water.

11. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,246 reviews)
"Beautiful views, excellent location, excellent service"
United States
Karen
The price is €95
includes taxes & fees
13 Oct - 14 Oct
Plaza Paitilla Inn Hotel
A modern outdoor swimming pool with a clear view of a tall building in the background.

12. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (35 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is €156
includes taxes & fees
3 Oct - 4 Oct
Dovle Residences by HMS-Preferred Member
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

13. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,115 reviews)
"The breakfast was great and the rooms were comfortable"
United States
Armando
The price is €147
includes taxes & fees
11 Oct - 12 Oct
Las Americas Golden Tower Panama
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

14. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (681 reviews)
"Great Breakfast!!"
United States
Cassandre
The price is €173
includes taxes & fees
30 Oct - 31 Oct
Residence Inn by Marriott Panama City
A rooftop pool with lounge chairs, offering a city view.

15. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (48 reviews)
"Excellent apartment and service."
United States
Dustin M
The price is €133
includes taxes & fees
6 Oct - 7 Oct
Boutique Apartments Atlapa
A modern hotel building with a prominent glass facade and the name 'THE HUB' displayed.

16. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is €160
includes taxes & fees
4 Oct - 5 Oct
The Hub by Boutique Apartments
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

17. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is €197
includes taxes & fees
30 Sept - 1 Oct
Wanders Panama by Boutique Apartments
A restaurant with a modern glass facade, wooden seating, and a sign indicating valet parking.

18. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
7.4 out of 10, Good, (3 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is €77
includes taxes & fees
30 Sept - 1 Oct
Modern Apartments PH Living 73 SF
A rooftop terrace with outdoor seating, a glass kitchen area, and a view of the city skyline.

19. PAN - TH - 2B (17E)

PAN - TH - 2B (17E)
2.0 star property
San Francisco
The price is €187
includes taxes & fees
12 Oct - 13 Oct
PAN - TH - 2B (17E)
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

20. Cozy Urban Loft 1br Near Coast

Cozy Urban Loft 1br Near Coast
2.0 star property
San Francisco
The price is €130
includes taxes & fees
3 Oct - 4 Oct
Cozy Urban Loft 1br Near Coast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,014 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,246 reviews
View
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,009 reviews
View
A modern building with a glass facade, a curved structure, and a flat roof.
Decapolis Hotel Panama City
4.0 star property
8.6
Excellent
1,727 reviews
View
A buffet with various food items and a decorative plant.
Sheraton Grand Panama
4.0 star property
8.6
Excellent
1,002 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A harbor with several boats docked in the foreground and a city skyline in the background.
Photo by Journey Of A Nomadic Family
Open Photo by Journey Of A Nomadic Family

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top San Francisco Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"The room was so clean, the staff was so help full. The hotel is next to the Múlti Plaza so well located."
Dailexy 1-night trip
Posted 2 hours ago
Courtyard by Marriott Panama Multiplaza Mall

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Ramada Plaza by Wyndham Panama Punta Pacifica and Decapolis Hotel Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 322 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Multicentro Panama might be the perfect way to find that souvenir you've been looking for. Calle 50 and Via Espana are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Bingo 90, Pacific Center and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.