San Francisco

Panama City

A bridge over a body of water with several boats.
A beach with a large driftwood piece, calm water, and a few people in the distance.
A city skyline with a flag, a river, and a park.
A cityscape with a distinctive twisted skyscraper, a busy highway, and surrounding modern buildings.
A cityscape with a rainbow over buildings.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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Top hotels in San Francisco

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is €124 per night from 26 Jul to 27 Jul
€124
26 Jul - 27 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very good! (1,586 reviews)
"The room was clean and well stocked. The breakfast was excellent with lots of variety."

Reviewed on 9 Jul 2026

Megapolis Hotel Panamá
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is €292 per night from 25 Jul to 26 Jul
€292
25 Jul - 26 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
"Súper tranquilo y muy limpio todo y el trato de los trabajadores muy cordial"

Reviewed on 7 Jul 2026

JW Marriott Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9/10 Wonderful! (1,055 reviews)
"Staff was warm, attentive, and efficient. The reason I stay there. Too bad one cannot charge room service to front desk. Paying every single time is a true nuisance. I don’t like strangers spending time inside my room to charge for food service. It’s an intrusion. Separate spa company is a true inconvenience. ..."

Reviewed on 10 Jul 2026

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Las Americas Golden Tower Panama
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is €118 per night from 24 Jul to 25 Jul
€118
24 Jul - 25 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and a nightclub. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,010 reviews)
"Everyone was really nice and helpful"

Reviewed on 8 Jul 2026

Aloft by Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is €105 per night from 25 Jul to 26 Jul
€105
25 Jul - 26 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,014 reviews)
"Lo mejor de este hotel es la ubicación xq queda dentro del centro comercial multiplaza el mejor de Panamá, las habitaciones son pequeñas para lo q cuesta pero la ubicación compensa"

Reviewed on 9 Jul 2026

Courtyard by Marriott Panama Multiplaza Mall
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is €134 per night from 8 Aug to 9 Aug
€134
8 Aug - 9 Aug
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,007 reviews)
"Convention going on but i had to ask to be compensated for all of the congestion and inconvenience and the manager complied. Well done for customer (me)."

Reviewed on 9 Jul 2026

Sheraton Grand Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Pacific Center while you're in town.

San Francisco

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