What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Ramada Plaza by Wyndham Panama Punta Pacifica and Decapolis Hotel Panama City .

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 323 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Pacific Center are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Bingo 90, Soho City Center and National Shrine of the Heart of Mary. When you're sightseeing in Panama City, Panama Viejo Museum and Multicentro Panama are also worth a stop.

San Francisco hotels, Panama City, Panama: Panama City Hotel Guide

A bridge over a body of water with several boats.

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Our top choices for San Francisco hotels

A balcony with wicker chairs and a view of the cityscape.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

Luis

includes taxes & fees

9 Nov - 10 Nov

A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

2. Courtyard by Marriott Panama Multiplaza Mall

San Francisco

SHARROW

includes taxes & fees

31 Oct - 1 Nov

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

3. Aloft by Marriott Panama

San Francisco

ANDRELL

includes taxes & fees

16 Oct - 17 Oct

A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

4. Living 73 Panamá by Boutique Apartments

San Francisco

Lorenz

includes taxes & fees

1 Nov - 2 Nov

A modern building with a glass facade, a curved structure, and a flat roof.

5. Decapolis Hotel Panama City

San Francisco

Jorge Luis

includes taxes & fees

31 Oct - 1 Nov

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

6. Boutique Apartments Panamá Coco del Mar

San Francisco

purabi

includes taxes & fees

11 Oct - 12 Oct

A rooftop pool with lounge chairs, offering a city view.

7. Boutique Apartments Atlapa

San Francisco

Gary

includes taxes & fees

11 Oct - 12 Oct

8. San Francisco by Wynwood House

San Francisco

Georg

includes taxes & fees

13 Oct - 14 Oct

A covered outdoor seating area with a view of a city skyline and water.

9. Plaza Paitilla Inn Hotel

San Francisco

Milton

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

10. Casa Orquídea

San Francisco

Brett

includes taxes & fees

15 Oct - 16 Oct

A buffet with various food items and a decorative plant.

11. Sheraton Grand Panama

San Francisco

Nicole

includes taxes & fees

31 Oct - 1 Nov

A playground with slides and climbing structures, surrounded by a fenced area with a view of tall buildings.

12. The Hub by Boutique Apartments

San Francisco

includes taxes & fees

20 Oct - 21 Oct

A modern outdoor swimming pool with a clear view of a tall building in the background.

13. Dovle Residences by HMS-Preferred Member

San Francisco

David

includes taxes & fees

9 Nov - 10 Nov

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

14. Megapolis Hotel Panamá

San Francisco

benjamin

includes taxes & fees

31 Oct - 1 Nov

A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

15. Cozy Urban Loft 1br Near Coast

San Francisco

includes taxes & fees

11 Oct - 12 Oct

A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

16. Residence Inn by Marriott Panama City

San Francisco

david

includes taxes & fees

29 Oct - 30 Oct

A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

17. Las Americas Golden Tower Panama

San Francisco

Armando

includes taxes & fees

18 Oct - 19 Oct

A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

18. Wanders Panama by Boutique Apartments

San Francisco

Gary

includes taxes & fees

2 Nov - 3 Nov

A restaurant with a modern glass facade, wooden seating, and a sign indicating valet parking.

19. Modern Apartments PH Living 73 SF

San Francisco

Dawid

includes taxes & fees

10 Oct - 11 Oct

A spa area with two hot tubs and lounge chairs.

20. 2BR at First del Sol Modern & Stylish

San Francisco

includes taxes & fees

23 Oct - 24 Oct

View all properties

Compare popular hotels in San Francisco

Property	Property class	Guest rating
Aloft by Marriott Panama	3.5 star property	8.8 Excellent 1,000 reviews	View
Courtyard by Marriott Panama Multiplaza Mall	4.0 star property	9.0 Wonderful 1,008 reviews	View
Las Americas Golden Tower Panama	4.0 star property	9.0 Wonderful 1,121 reviews	View
Residence Inn by Marriott Panama City	4.0 star property	9.2 Wonderful 686 reviews	View
Dovle Residences by HMS-Preferred Member	4.0 star property	8.6 Excellent 38 reviews	View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

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A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

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A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

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