San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Panama City Visit an Indian town Embera and waterfall with lunch
€38
per adult
96% of travellers recommend
Panama City: POIN Swing Experience
€28
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
€28
per adult
100% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
€85
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
€58
per adult
98% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is €124 per night from 26 Jul to 27 Jul
€124
per night
26 Jul - 27 Jul
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very good! (1,586 reviews)
"The room was clean and well stocked. The breakfast was excellent with lots of variety."
Reviewed on 9 Jul 2026
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is €292 per night from 25 Jul to 26 Jul
€292
per night
25 Jul - 26 Jul
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
"Súper tranquilo y muy limpio todo y el trato de los trabajadores muy cordial"
Reviewed on 7 Jul 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9/10 Wonderful! (1,055 reviews)
"Staff was warm, attentive, and efficient. The reason I stay there. Too bad one cannot charge room service to front desk. Paying every single time is a true nuisance. I don’t like strangers spending time inside my room to charge for food service. It’s an intrusion. Separate spa company is a true inconvenience. ..."
Reviewed on 10 Jul 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is €118 per night from 24 Jul to 25 Jul
€118
per night
24 Jul - 25 Jul
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and a nightclub. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,010 reviews)
"Everyone was really nice and helpful"
Reviewed on 8 Jul 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is €105 per night from 25 Jul to 26 Jul
€105
per night
25 Jul - 26 Jul
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,014 reviews)
"Lo mejor de este hotel es la ubicación xq queda dentro del centro comercial multiplaza el mejor de Panamá, las habitaciones son pequeñas para lo q cuesta pero la ubicación compensa"
Reviewed on 9 Jul 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is €134 per night from 8 Aug to 9 Aug
€134
per night
8 Aug - 9 Aug
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,007 reviews)
"Convention going on but i had to ask to be compensated for all of the congestion and inconvenience and the manager complied. Well done for customer (me)."
Reviewed on 9 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by My World
Open Photo by My World
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.
Punta Paitilla
Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Pacific Center while you're in town.
