San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
€41
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
€85
per adult
94% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
€28
per adult
100% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
€125
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
€57
per adult
96% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
€52
per adult
100% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is €133 per night from 31 Oct to 1 Nov
€133
31 Oct - 1 Nov
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,780 reviews)
"Awesome hotel, friendly an helpful staff, clean and super convenient location Room prices are good and food was good in taste and price Definitely returning with my family cause I know my kids would love it there"
Reviewed on 9 Oct 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
The price is €103 per night from 9 Nov to 10 Nov
€103
9 Nov - 10 Nov
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,384 reviews)
"All ok"
Reviewed on 9 Oct 2026
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
The price is €85 per night from 31 Oct to 1 Nov
€85
31 Oct - 1 Nov
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is €116 per night from 31 Oct to 1 Nov
€116
31 Oct - 1 Nov
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,008 reviews)
"Nice Place to Stay in Panama"
Reviewed on 9 Oct 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is €123 per night from 17 Oct to 18 Oct
€123
17 Oct - 18 Oct
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and a nightclub. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,000 reviews)
"Clean room"
Reviewed on 5 Oct 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
The price is €149 per night from 18 Oct to 19 Oct
€149
18 Oct - 19 Oct
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9/10 Wonderful! (1,121 reviews)
"Great views, great breakfast each morning, friendly staff, central location. The only downfall was climate control, the rooms were very humid causing our room to be musty. They did provide and humidifier which helped. Overall a wonderful experience for our first time in Panama."
Reviewed on 8 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.
