Panama City Holidays
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Casco Viejo
3.5/5(3 area reviews)
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.
Top hotels in Panama City
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is €116 per night from 22 Jan to 23 Jan
€116
22 Jan - 23 Jan
includes taxes & fees
9/10 Wonderful! (4,807 reviews)
5 🌟
Reviewed on 6 Jan 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
8.4/10 Very Good! (1,351 reviews)
El hotel nos brindó una excelente atención.
Reviewed on 4 Jan 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is €143 per night from 27 Jan to 28 Jan
€143
27 Jan - 28 Jan
includes taxes & fees
8.8/10 Excellent! (1,014 reviews)
Going location, great city views
Reviewed on 4 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Panama City
City Sightseeing Panama City Hop-On Hop-Off Bus Tour
€26
per adult
80% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
€84
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
€57
per adult
98% of travellers recommend
Explore a world of travel with Expedia
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- Flights to Panama City
- Flights from Aioun el Atrouss (AEO) to Panama City (PAC)
- Flights from N'Zeto (ARZ) to Panama City (PAC)
- Flights from The Valley (AXA) to Panama City (PAC)
- Flights from Berlin (BER) to Panama City (PAC)
- Flights from Bikini (BII) to Panama City (PAC)
- Flights from Bocas del Toro (BOC) to Panama City (PAC)
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- Flights from Chambery (CMF) to Panama City (PAC)
- Flights from Cartagena (CTG) to Panama City (PAC)
- Flights from Saint-Etienne (EBU) to Panama City (PAC)
- Flights from Forster (FOT) to Panama City (PAC)
- Flights from Fort Pierce (FPR) to Panama City (PAC)
- Flights from Gatokae (GTA) to Panama City (PAC)
- Flights from Haikou (HAK) to Panama City (PAC)
- Flights from New York (JFK) to Panama City (PAC)
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- Flights from Geraldton (YGQ) to Panama City (PAC)
- Flights from Wemindji (YNC) to Panama City (PAC)
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
