Otay Mesa West
San Diego
Visit Otay Mesa West
Popular places to visit
San Diego Zoo
Come and see the power and beauty of nature up close at one of the biggest and best zoos in America.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
USS Midway Museum
Climb aboard the USS Midway for a fascinating historical view on naval life and changes in technology through the 20th century.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
Enjoy the old-world charm of this seaside suburb where the beautiful people live, close to central San Diego.
Things to do
Oceanside Whale and Dolphin Watching Adventures
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego: Luggage Storage in Marina
Top hotels in Otay Mesa West
The Sofia Hotel
Clean, safe and well located. Reasonably priced.
Reviewed on 12 May 2026
Paradise Point Resort & Spa
did not get information about breakfast, fridge was not working( water was coming out of it) parking was 50 dollars a day. On top of paying 900 for a room for 3 days, my card was charged 605.
Reviewed on 12 May 2026
Hard Rock Hotel San Diego
We celebrated a birthday here and the hotel staff went out of their way to make it extra special for us. Thank you!!
Reviewed on 12 May 2026
Manchester Grand Hyatt San Diego
Great location and clean hotel.
Reviewed on 9 May 2026
The DEXTRO Little Italy, BW Premier Collection
The room was clean. We did have to call for room service. It seems like they don’t do it unless you call. There is also no microwave, which is annoying. But the room was clean and the pool/rec area was nice.
Reviewed on 11 May 2026
Wyndham San Diego Bayside
Clean room and a beautiful view of the harbor. Plenty of elevators and easy access.
Reviewed on 12 May 2026
Other neighbourhoods around Otay Mesa West
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Point Loma
Seaside views a bustling port and top sights from Shelter Island to Humphreys Concerts by the Bay – discover Point Loma, a destination also famous for its island views.
