San Diego Hotel Guide. Hotels in Otay Mesa West, San Diego, United States of America

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Our top choices for Otay Mesa West hotels

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 17.8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1007)
"An excellent stay in an excellent area! Super clean and staff is very nice."
Canada
Emily
The price is €98
includes taxes & fees
6 Jan - 7 Jan
Staypineapple, Hotel Z, Gaslamp San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 27.9 km from Otay Mesa West
8.8 out of 10, Excellent, (2375)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is €172
includes taxes & fees
11 Jan - 12 Jan
Paradise Point Resort & Spa

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1476)
"Very nice staff and clean rooms"
United States
Desserae
The Bristol Hotel San Diego

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 26.7 km from Otay Mesa West
8.4 out of 10, Very good, (1326)
"Loved the bay front room with the large grass area right out the door!"
United States
Todd and Danielle
The price is €180
includes taxes & fees
13 Jan - 14 Jan
San Diego Mission Bay Resort

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3619)
"The hotel and staff were great. "
United States
Rosa
The price is €112
includes taxes & fees
6 Jan - 7 Jan
Best Western Plus Marina Gateway Hotel

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6040)
"Perfect location for leaving on a cruise!"
United States
Hope
The price is €155
includes taxes & fees
7 Jan - 8 Jan
Wyndham San Diego Bayside

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
18.7 km from Otay Mesa West
9.0 out of 10, Wonderful, (1088)
"Loved my stay! Def plan to stay here again "
United States
Lizbeth Flores
The price is €147
includes taxes & fees
6 Jan - 7 Jan
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (2902)
"Excellent stay...wonderful staff"
United States
Michelle
The price is €229
includes taxes & fees
9 Jan - 10 Jan
Manchester Grand Hyatt San Diego

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
9.7 km from Otay Mesa West
8.8 out of 10, Excellent, (1066)
"The staff and amenities were spectacular. "
United States
Andrew
The price is €230
includes taxes & fees
6 Jan - 7 Jan
Loews Coronado Bay Resort

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 17.9 km from Otay Mesa West
9.2 out of 10, Wonderful, (1985)
"Great place for families!!"
Canada
Ilijana
The price is €237
includes taxes & fees
9 Jan - 10 Jan
Marriott Marquis San Diego Marina

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
23.5 km from Otay Mesa West
8.4 out of 10, Very good, (1464)
"Staff, rooms, pools, and price..very good! "
United States
James
The price is €116
includes taxes & fees
11 Jan - 12 Jan
DoubleTree by Hilton Hotel San Diego - Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
22.9 km from Otay Mesa West
9.2 out of 10, Wonderful, (2958)
"Enjoyed my stay. Clean rooms, nice staff, will come back again "
United States
Oscar
Legacy Resort Hotel & Spa

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (1020)
"Great hotel, excellent location, excellent view on rooftop!"
United States
Rajeev
The price is €105
includes taxes & fees
6 Jan - 7 Jan
Gaslamp Plaza Suites

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very good, (1902)
"The staff was very nice and great location"
United States
Curtis
The price is €87
includes taxes & fees
11 Jan - 12 Jan
GreenTree Inn San Diego Mission Bay

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 19.2 km from Otay Mesa West
8.8 out of 10, Excellent, (186)
"Great place to stay "
United States
Jacorey
The price is €123
includes taxes & fees
6 Jan - 7 Jan
Courtyard by Marriott San Diego Downtown Little Italy

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
22.1 km from Otay Mesa West
9.2 out of 10, Wonderful, (3257)
"Great stay and location!"
United States
Jason
The price is €105
includes taxes & fees
6 Jan - 7 Jan
Bay Club Hotel & Marina

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1659)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3203)
"Beautiful hotel"
United States
Jordan M.
The price is €510
includes taxes & fees
3 Feb - 4 Feb
Hard Rock Hotel San Diego

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
22.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (2744)
"Great stay, highly recommend."
United States
Ryan
The price is €163
includes taxes & fees
6 Jan - 7 Jan
Humphreys Half Moon Inn

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
23.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1354)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
United States
bill
The price is €88
includes taxes & fees
19 Jan - 20 Jan
Hampton Inn San Diego/Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

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