What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

Otay Mesa West hotels, San Diego, United States of America: San Diego Hotel Guide

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Our top choices for Otay Mesa West hotels

1. Best Western Americana Inn

2.1 km from Otay Mesa West

Luis

includes taxes & fees

13 Sept - 14 Sept

2. Studio 6 Suites San Ysidro, CA -San Diego South Bay

3.1 km from Otay Mesa West

Arnold

includes taxes & fees

23 Aug - 24 Aug

Premium bedding, desk, blackout curtains, soundproofing

3. Valli Hi Motel

2.2 km from Otay Mesa West

elizabeth E

includes taxes & fees

20 Aug - 21 Aug

4. Comfort Inn Chula Vista San Diego South

7.9 km from Otay Mesa West

Katsuya

includes taxes & fees

13 Sept - 14 Sept

5. La Quinta Inn by Wyndham San Diego Chula Vista

7.8 km from Otay Mesa West

Luis

includes taxes & fees

30 Aug - 31 Aug

6. Holiday Inn Express San Diego South - Chula Vista by IHG

8 km from Otay Mesa West

Jose

includes taxes & fees

7 Sept - 8 Sept

7. Hercor Hotel - Urban Boutique

6.8 km from Otay Mesa West

Keane

includes taxes & fees

10 Sept - 11 Sept

8. Ayres Hotel San Diego South - Chula Vista

9.2 km from Otay Mesa West

Evelyn

includes taxes & fees

3 Sept - 4 Sept

9. The Rambler Hotel

8 km from Otay Mesa West

Tracy

includes taxes & fees

17 Sept - 18 Sept

Standard Single Room, 1 King Bed, Non Smoking

10. Hotel Palmeras Chula Vista

7.8 km from Otay Mesa West

Suksan

includes taxes & fees

20 Aug - 21 Aug

11. Best Western Chula Vista/Otay Valley Hotel

2.4 km from Otay Mesa West

Gustavo

includes taxes & fees

7 Sept - 8 Sept

Premium bedding, in-room safe, desk, laptop workspace

12. Best Western Plus Marina Gateway Hotel

10.5 km from Otay Mesa West

Samuel

includes taxes & fees

7 Sept - 8 Sept

Studio Suite, 1 King Bed with Sofa bed, Balcony | View from room

13. Sheraton San Diego Resort

21.4 km from Otay Mesa West

Andre

includes taxes & fees

6 Sept - 7 Sept

14. Hotel Z

Gaslamp Quarter, 17.8 km from Otay Mesa West

Efrain

includes taxes & fees

1 Sept - 2 Sept

Outdoor pool, pool cabanas (surcharge), pool umbrellas

15. Sun Outdoors San Diego Bay

8.2 km from Otay Mesa West

Faebyan

includes taxes & fees

7 Sept - 8 Sept

16. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

11 km from Otay Mesa West

Yaril

includes taxes & fees

23 Aug - 24 Aug

17. Hilton San Diego Bayfront

Marina District, 17.2 km from Otay Mesa West

Gina

includes taxes & fees

7 Sept - 8 Sept

Premium bedding, pillow-top beds, laptop workspace, free WiFi

18. The Margot Hotel San Diego Gaslamp Quarter, Outset by Hilton

East Village, 17.6 km from Otay Mesa West

Diane

includes taxes & fees

7 Sept - 8 Sept

19. Hard Rock Hotel San Diego

Gaslamp Quarter, 17.5 km from Otay Mesa West

Anthony

includes taxes & fees

24 Aug - 25 Aug

20. Kings Inn San Diego

23.1 km from Otay Mesa West

Manuel

includes taxes & fees

31 Aug - 1 Sept

View all properties

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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A beach with surfers and swimmers during sunset.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

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A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

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Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

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An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

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Top Otay Mesa West Hotel Reviews

Bay Club Hotel & Marina

8/10 Good

"Enjoyed our stay. Breakfast was great. Rooms were spacious. Marina views were nice. Really enjoyed walkability to coffee, etc."

Hard Rock Hotel San Diego

10/10 Excellent

"We had an amazing stay at the Hard Rock Hotel San Diego! The hotel was clean, the customer service was excellent, and everyone was so friendly and helpful. The luggage and valet staff were especially amazing throughout our entire stay. Our room also had an incredible view overlooking Petco Park—it honestly felt like having a rooftop bar right outside our window! We couldn’t have asked for a better experience and would absolutely stay here again."

Omni San Diego Hotel at the Ballpark

10/10 Excellent

"We had the best weekend stay at the Omni! We were in San Diego for a concert at Petco Park, and the location couldn’t have been more perfect. Being right next to the stadium made the entire experience so easy and enjoyable, and the VIP stadium access was such an amazing perk. We also loved spending time at the pool and really appreciated how friendly and welcoming all of the staff were throughout our stay. Everyone went above and beyond to make us feel taken care of. It was the perfect hotel for our weekend getaway, and we had such a great time from start to finish. We’ll definitely be back! ❤️"

Paradise Point Resort & Spa

10/10 Excellent

"We stayed at an inside bungalow which was fine on this beautifully landscaped property. We were on a small lake with a fountain that was relaxing. Also, there was plenty of things to do including climbing the tower, feeding the ducks and fish, and walking around the grounds. The Barefoot Bar is one of my favorite places to eat and drink with a great view and delicious food."

San Diego Hotel Guide. Hotels in Otay Mesa West, San Diego, United States of America

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Otay Mesa West hotels

1. Best Western Americana Inn

2. Studio 6 Suites San Ysidro, CA -San Diego South Bay

3. Valli Hi Motel

4. Comfort Inn Chula Vista San Diego South

5. La Quinta Inn by Wyndham San Diego Chula Vista

6. Holiday Inn Express San Diego South - Chula Vista by IHG

7. Hercor Hotel - Urban Boutique

8. Ayres Hotel San Diego South - Chula Vista

9. The Rambler Hotel

10. Hotel Palmeras Chula Vista

11. Best Western Chula Vista/Otay Valley Hotel

12. Best Western Plus Marina Gateway Hotel

13. Sheraton San Diego Resort

14. Hotel Z

15. Sun Outdoors San Diego Bay

16. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

17. Hilton San Diego Bayfront

18. The Margot Hotel San Diego Gaslamp Quarter, Outset by Hilton

19. Hard Rock Hotel San Diego

20. Kings Inn San Diego

Where to stay in Otay Mesa West

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Otay Mesa West Hotel Reviews

Bay Club Hotel & Marina

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