San Francisco hotels, Panama City, Panama: Panama City Hotel Guide

The Bridge of the Americas in summer, Panama City

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in San Francisco

Property	Property class	Guest rating
Plaza Paitilla Inn Hotel	3.5 star property	9.4 Exceptional 2,181 reviews	View
Aloft by Marriott Panama	3.5 star property	8.8 Excellent 1,015 reviews	View
Courtyard by Marriott Panama Multiplaza Mall	4.0 star property	9.0 Wonderful 1,007 reviews	View
San Francisco by Wynwood House	3.0 star property	9.2 Wonderful 56 reviews	View
Sheraton Grand Panama	4.0 star property	8.6 Excellent 1,002 reviews	View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

See properties

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

See properties

Panama City Old Town streets and buildings

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

See properties

Panoramic view of Panama City Skyline - Panama City, Panama

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

See properties

Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

See properties

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"The stay at Riu was fantastic. The staff were friendly and very helpful. Our family suite was so spacious and offered many amenities. Located on the 32nd floor, the views of the city were astounding. The breakfast was the best part of the stay. There were plenty of offerings and everything tasted so delicious. The hotel lobby smelled amazing but whatever products they use to clean the rooms did not smell as great and the ladies bathroom in the lobby had a very strong and unpleasant odor. It smelled musty and as if the whole bathroom needed to be aired out. The two times I tried to use the bathroom, I could barely stay in there."

MARINN PLACE Financial District

6/10 Okay

"Great location and nice view (you can walk to the metro, pharmacy and to tons of restaurants and coffee shops) but lobby staff needs to be a bit friendlier. Fortunately the rest of the staff is polite and friendly (cleaning lady and restaurant staff). There are only three elevators for 18 floors and they work when and how they want. During our stay they had to repair two, so most of the time one was out of order (the repairs went into the night with very loud “bangs”). In addition, the hotel seems to be updating its lightning system, so you have to go around the electricians, plaster and ladders. The pool is really small and the breakfast is ok (more fruits would have been awesome). It is a really busy place."

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Sheraton Grand Panama is one of the top choices for your stay in San Francisco. This resort is a short 13-minute walk from Multiplaza Pacific Mall, and it offers a full-service spa and 3 restaurants. Other good choices for your stay in the area include Las Americas Golden Tower Panama and Courtyard by Marriott Panama Multiplaza Mall.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 320 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Pacific Center. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.

Panama City Hotel Guide. Hotels in San Francisco, Panama City, Panama

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for San Francisco hotels

Dovle Residences by HMS-Preferred Member

Sheraton Grand Panama

Aloft by Marriott Panama

Modern Apartments PH Living 73 SF

Plaza Paitilla Inn Hotel

Boutique Apartments Panamá Coco del Mar

San Francisco by Wynwood House

Stylish Apartment With Pool Gym in Panama

Courtyard by Marriott Panama Multiplaza Mall

JW Marriott Panama

Megapolis Hotel Panamá

Serenade Lodging Rooms

Casa Orquídea

Decapolis Hotel Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

Modern Apartments at the Hub City views

Residence Inn by Marriott Panama City

Cozy Urban Loft 1br Near Coast

Las Americas Golden Tower Panama

Boutique Apartments Atlapa

Compare popular hotels in San Francisco

Where to stay in San Francisco

Casco Viejo

Bella Vista

El Cangrejo

Calidonia

San Felipe

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

Frequently asked questions