Madrid Hotel Guide. Hotels in San Isidro, Madrid, Spain

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near San Isidro, Madrid

Front of property
CIELO Madrid Studios

CIELO Madrid Studios

4.0 star property
San Isidro
8.8 out of 10, Excellent, (351)
"The hotel is clean and appropriate for families "
Netherlands
Karima
The price is €77
includes taxes & fees
4 Dec - 5 Dec
CIELO Madrid Studios
Porch
Hotel Riu Plaza España

Hotel Riu Plaza España

4.0 star property
3.4 km from San Isidro
9.4 out of 10, Exceptional, (4557)
"Amazing location, beautiful hotel, great staff.. very helpful and polite. "
United States
TIEN
The price is €157
includes taxes & fees
8 Dec - 9 Dec
Hotel Riu Plaza España
Superior Double Room
B&B Hotel Madrid Centro F52

B&B Hotel Madrid Centro F52

2.5 star property
Chueca, 3.8 km from San Isidro
9.4 out of 10, Exceptional, (526)
"Great Location and updated modern room with some character."
United States
IGOR
The price is €125
includes taxes & fees
15 Dec - 16 Dec
B&B Hotel Madrid Centro F52
Premium bedding, Select Comfort beds, minibar, in-room safe
Barceló Torre de Madrid

Barceló Torre de Madrid

5.0 star property
3.4 km from San Isidro
9.4 out of 10, Exceptional, (2248)
"Lovely stay, good location and fantastic breakfast."
United Kingdom
Darren
The price is €221
includes taxes & fees
14 Dec - 15 Dec
Barceló Torre de Madrid
Spanish cuisine
Zleep Hotel Madrid Airport

Zleep Hotel Madrid Airport

3.0 star property
16.1 km from San Isidro
8.6 out of 10, Excellent, (2495)
"Great rooms and breakfast "
United States
James
The price is €72
includes taxes & fees
8 Dec - 9 Dec
Zleep Hotel Madrid Airport
Terrace/patio
Atipico Madrid

Atipico Madrid

2.5 star property
Salamanca, 6.3 km from San Isidro
8.4 out of 10, Very good, (107)
"Very good Hotel Come back soon. "
United States
Miguel
The price is €92
includes taxes & fees
18 Dec - 19 Dec
Atipico Madrid
Suite Exterior (Aduana)
Hotel Regina

Hotel Regina

4.0 star property
Sol, 3.4 km from San Isidro
9.8 out of 10, Exceptional, (2194)
"Beautiful hotel. Great location "
United States
Marlene
The price is €426
includes taxes & fees
26 Dec - 27 Dec
Hotel Regina
Terrace/patio
Barceló Imagine

Barceló Imagine

5.0 star property
Chamartín, 9 km from San Isidro
9.6 out of 10, Exceptional, (1000)
"The decorations, room and staff were all amazing. "
United States
Giovanni
The price is €182
includes taxes & fees
25 Dec - 26 Dec
Barceló Imagine
Classic Room, Terrace | Terrace/patio
H10 Puerta de Alcalá 4* Sup

H10 Puerta de Alcalá 4* Sup

4.0 star property
Recoletos, 4.9 km from San Isidro
9.2 out of 10, Wonderful, (1017)
"The staff was friendly and effective, the hotel was beautiful, the room was perfect and the common areas were nice too."
United States
Ignacio
The price is €147
includes taxes & fees
25 Dec - 26 Dec
H10 Puerta de Alcalá 4* Sup
Lobby lounge
Madrid Marriott Hotel Princesa Plaza

Madrid Marriott Hotel Princesa Plaza

4.0 star property
Malasaña, 3.9 km from San Isidro
8.8 out of 10, Excellent, (1418)
"Todo excelente "
Mexico
Jose
The price is €195
includes taxes & fees
15 Dec - 16 Dec
Madrid Marriott Hotel Princesa Plaza
Terrace/patio
Hotel Fenix Gran Meliá - The Leading Hotels of the World

Hotel Fenix Gran Meliá - The Leading Hotels of the World

5.0 star property
Recoletos, 4.7 km from San Isidro
9.4 out of 10, Exceptional, (1000)
"I love this hotel. Have stayed here several times. The service and staff are amazing. "
United States
Omar
The price is €324
includes taxes & fees
8 Dec - 9 Dec
Hotel Fenix Gran Meliá - The Leading Hotels of the World
Lobby
Hotel Nido Príncipe Pío

Hotel Nido Príncipe Pío

3.0 star property
2.8 km from San Isidro
8.8 out of 10, Excellent, (409)
"Good hotel"
United States
Yisel
The price is €81
includes taxes & fees
14 Dec - 15 Dec
Hotel Nido Príncipe Pío
Lunch and dinner served
ICON Embassy

ICON Embassy

4.0 star property
Recoletos, 4.8 km from San Isidro
9.4 out of 10, Exceptional, (942)
"Great location. "
United States
Anabel
The price is €192
includes taxes & fees
4 Dec - 5 Dec
ICON Embassy
Pool
Eurostars Madrid Tower

Eurostars Madrid Tower

5.0 star property
9.5 km from San Isidro
8.6 out of 10, Excellent, (1000)
"It’s a great hotel , with great staff "
United States
Kenneth
The price is €174
includes taxes & fees
1 Jan - 2 Jan 2026
Eurostars Madrid Tower
Miscellaneous
Novotel Madrid Center

Novotel Madrid Center

4.0 star property
Salamanca, 5.5 km from San Isidro
9.2 out of 10, Wonderful, (1000)
"Clean rooms, staff very nice, and very good breakfast. "
United States
Bogdan
The price is €169
includes taxes & fees
1 Jan - 2 Jan 2026
Novotel Madrid Center
Indoor pool, outdoor pool, open 4:00 PM to 8:00 PM, pool loungers
Hilton Madrid Airport

Hilton Madrid Airport

4.0 star property
Barajas, 13.5 km from San Isidro
9.0 out of 10, Wonderful, (1220)
"Have stayed here before, great staff, very clean rooms & a delightful bar area for cosy drinks in front of a fire."
United Kingdom
Susan
The price is €122
includes taxes & fees
21 Dec - 22 Dec
Hilton Madrid Airport
Hypo-allergenic bedding, down duvets, minibar, in-room safe
Hotel Exe Plaza

Hotel Exe Plaza

4.0 star property
8.5 km from San Isidro
8.6 out of 10, Excellent, (1003)
"Great location"
Canada
Campbell
The price is €100
includes taxes & fees
21 Dec - 22 Dec
Hotel Exe Plaza
Lobby
Hotel Acta Madfor

Hotel Acta Madfor

3.0 star property
2.8 km from San Isidro
8.6 out of 10, Excellent, (1017)
"Excellent hotel."
United States
JULIETA
The price is €95
includes taxes & fees
9 Dec - 10 Dec
Hotel Acta Madfor
Exterior
Hotel Claridge Madrid

Hotel Claridge Madrid

4.0 star property
5.1 km from San Isidro
9.2 out of 10, Wonderful, (1012)
"We were happy with our stay here, we recommend it! "
Canada
Mustafa
The price is €165
includes taxes & fees
4 Dec - 5 Dec
Hotel Claridge Madrid
Daily buffet breakfast (EUR 45 per person)
Wellington Hotel & Spa Madrid

Wellington Hotel & Spa Madrid

5.0 star property
Recoletos, 4.7 km from San Isidro
9.4 out of 10, Exceptional, (1000)
"Great place "
United States
Isaac Luis
The price is €390
includes taxes & fees
14 Dec - 15 Dec
Wellington Hotel & Spa Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Isidro

Find the best San Isidro areas for the activities you enjoy most.

Madrid Centro

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Gran Via and Puerta del Sol, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

Sol

If you're spending time in Sol, check out sights like Gran Via or Puerta del Sol and hop on the metro to see more of the city at Sol Station or Callao Station.

Salamanca

Contemporary fashion, gourmet cuisine, fine art and upscale residential living await discovery in one of Madrid’s most stylish neighborhoods.

Chueca featuring a city and café scenes as well as a large group of people

Chueca

This avant-garde part of Madrid is known as the gay quarter because of its numerous LGBT shops and bars, a Gay Pride march and an open-minded populace.

Malasaña

Loved by hipsters and students for its coffeehouses and nightlife scene, this creative neighborhood also has excellent art museums, theaters and shopping.

Top San Isidro Hotel Reviews

Barceló Torre de Madrid

Barceló Torre de Madrid

10/10 Excellent
"Everything was really good we had a great experience. Very Professional staff Lucia and Williams at front desk were the best at check in, they really went above and beyond to make sure we had the best view and experience in our stay at this hotel, and the best part they had a great attitude and great smile at all times. Highly recommended."
Daniel 5-night trip
Posted 1 day ago
Barceló Torre de Madrid

Explore a world of travel with Expedia

Frequently asked questions

What is San Isidro like?
Travellers to the San Isidro neighbourhood in Madrid will be sure to enjoy their stay. Consider a visit to Ermita de San Isidro as part of your San Isidro travel plans.
How many hotels will I be able to find in the San Isidro area?
If you're searching for places to stay in Madrid, choose from one of Expedia's 13 hotels and other accommodation options in San Isidro.
If I need to cancel my hotel reservation in San Isidro, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer in San Isidro.
What is there to do in this Madrid neighbourhood?
Ermita de San Isidro is an attraction you might want to check out while you're in San Isidro. While you're out sightseeing in Madrid, make sure that you visit other sights such as Gran Via or Plaza Mayor.
How can I get around San Isidro and the greater Madrid area?
Ready to get out and explore the city? Marques de Vadillo Station is the closest metro station.