Sanibel Hotel Guide. Hotels in Sanctuary, Sanibel, United States of America

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Check prices for these dates

Tonight
24 Feb - 25 Feb
Tomorrow
25 Feb - 26 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

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Our top choices for Sanctuary hotels

Signature Cottage

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 12.8 km from Sanctuary
9.6 out of 10, Exceptional, (4 reviews)
"This hotel was perfect It was decorated beautifully and was so clean and the bed was so comfy and the rainfall shower was very nice, the room had everything you could need for a nice vacation there’s a market within walking distance which had everything you need to make your stay perfect highly recommend this hotel anytime we come back to Sanibel we will always stay here "
United States
Mary
The price is €263
includes taxes & fees
8 Mar - 9 Mar
The Anchor Inn
BBQ/picnic Area

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (238 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is €150
includes taxes & fees
24 Mar - 25 Mar
Matlacha on Shoreview
Suite, 2 Bedrooms, Marina View

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,006 reviews)
"Amazing room and view. Great place to stay/vacation. Would come back over and over again. "
United States
Frank
The price is €311
includes taxes & fees
15 Mar - 16 Mar
The Westin Cape Coral Resort At Marina Village
Lobby

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,004 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is €165
includes taxes & fees
1 Mar - 2 Mar
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Poolside bar

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,243 reviews)
"Nice room, great tiki bar and pool area, and friendly staff."
United States
Jason
The price is €122
includes taxes & fees
11 Mar - 12 Mar
Dolphin Key Resort
In-room safe, desk, laptop workspace, blackout curtains

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,258 reviews)
"Good place to stay"
United States
Rashad
The price is €143
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Balcony view

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,007 reviews)
"Great stay staff was great . Lake veiw was beautifully i definitely rerent rm 207. Has beautiful restaurant next door work price and ambience. "
United States
Rachel
The price is €88
includes taxes & fees
28 Feb - 1 Mar
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
Deluxe Suite (Second Floor Only) | Terrace/patio

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (152 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is €268
includes taxes & fees
4 Mar - 5 Mar
Off the Charts Inn & Out Island Resort
Deluxe Studio Suite | Terrace/patio

White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.2 out of 10, Very good, (51 reviews)
"Clean, easy access, quiet, best bed and sheets ever!!!"
United States
Brooke
The price is €140
includes taxes & fees
1 Mar - 2 Mar
White Orchid Apartments
Classic Studio | Living area

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very good, (12 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is €141
includes taxes & fees
3 Mar - 4 Mar
Summerwind Studios
Exterior

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.2 out of 10, Very good, (19 reviews)
"Great mattress, enjoyed the recliners, we prefer no doors on the closet making it fast & easy to access our wardrobe, liked the Roku TV, liked the induction stove top and drainer for washing our dishes daily as opposed to having a dishwasher. "
United States
Bobbi
The price is €137
includes taxes & fees
2 Mar - 3 Mar
TriLuxe Inn & Studios
Private beach nearby, motor boating, fishing

MALU LANI Inn & Marina

MALU LANI Inn & Marina
2.5 star property
24.7 km from Sanctuary
10.0 out of 10, Exceptional, (1 review)
"This is a great space. Quiet, serene, clean, comfortable and close to what you need. Our family of three had a great stay and highly recommend!"
United States
Taletha
The price is €264
includes taxes & fees
10 Mar - 11 Mar
MALU LANI Inn & Marina
On the beach, sun-loungers, beach towels

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,633 reviews)
"Staff is amazing, amenities are great and is so beautiful! "
United States
Erica
The price is €455
includes taxes & fees
5 Mar - 6 Mar
Sanibel Island Beach Resort
View from property

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1,011 reviews)
"Nice room and perfect location"
United States
Matthias
The price is €426
includes taxes & fees
26 Feb - 27 Feb
Marriott Sanibel Harbour Resort & Spa
Exterior

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.6 out of 10, Good, (1,003 reviews)
"Yes great place"
United States
Jason
The price is €113
includes taxes & fees
23 Mar - 24 Mar
Candlewood Suites Fort Myers Sanibel Gateway by IHG
Free daily buffet breakfast

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1,000 reviews)
"Clean room and friendly staff. "
United States
Cindy
The price is €192
includes taxes & fees
22 Mar - 23 Mar
Residence Inn by Marriott Fort Myers Sanibel
Terrace/patio

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,005 reviews)
"Great place"
United States
Brian
The price is €181
includes taxes & fees
22 Mar - 23 Mar
Hilton Garden Inn Ft Myers
Lobby lounge

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (831 reviews)
"Staff were great! "
United States
Karen
The price is €144
includes taxes & fees
8 Mar - 9 Mar
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Bar (on property)

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,006 reviews)
"Wonderful stay "
United States
Brandi
The price is €190
includes taxes & fees
22 Mar - 23 Mar
Doubletree by Hilton Fort Myers at Bell Tower Shops
Exterior

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Great room and the breakfast was delicious "
United States
Jackeline
The price is €170
includes taxes & fees
27 Mar - 28 Mar
Homewood Suites by Hilton - Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Periwinkle Way which includes cycling as well as an individual femail

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent
"Room was clean bed was comfortable breakfast was good. All the people were nice. "
John 1-night trip
Posted 1 day ago
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 10 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.