Sanibel Hotel Guide. Hotels in Sanctuary, Sanibel, United States of America

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Our top choices for Sanctuary hotels

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1093)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is €200
includes taxes & fees
11 Jan - 12 Jan
Lani Kai Beachfront Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1520)
"Great location. "
United States
Patricia
The price is €269
includes taxes & fees
11 Jan - 12 Jan
Sanibel Island Beach Resort

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1000)
"Spotless rooms , great breakfast , courteous staff ! Had a great time !"
United States
Arijit
The price is €140
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
21.5 km from Sanctuary
8.8 out of 10, Excellent, (1001)
"Great Place to Stay!"
United States
JUDY
The price is €125
includes taxes & fees
10 Jan - 11 Jan
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (914)
"Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. "
United States
Kimberly
Latitude 26 Waterfront Resort & Marina

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (799)
"Great price close to my amenities. "
Canada
Gerry
The price is €107
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1000)
"We absolutely love staying here. Everytime we visit florida we come to this hotel. They offer everything you need for a family of 6, makes vacationing alot easier for us parents!"
United States
Kassie
The price is €159
includes taxes & fees
20 Jan - 21 Jan
Residence Inn by Marriott Fort Myers Sanibel

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
20.4 km from Sanctuary
9.4 out of 10, Exceptional, (1225)
"Great place to stay"
United States
Robyn
The price is €282
includes taxes & fees
11 Jan - 12 Jan
Pink Shell Beach Resort and Marina

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
21.5 km from Sanctuary
8.6 out of 10, Excellent, (1594)
"Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach"
United States
Erika
The Lighthouse Resort Inn & Suites

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.0 out of 10, Very good, (1004)
"Nice pool area and hot tub. Nice breakfast and staff were polite and friendly. "
United Kingdom
Dennis
The price is €137
includes taxes & fees
19 Jan - 20 Jan
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1002)
"Great stay "
United States
Brandon
The price is €163
includes taxes & fees
11 Jan - 12 Jan
Doubletree by Hilton Fort Myers at Bell Tower Shops

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
21.6 km from Sanctuary
9.0 out of 10, Wonderful, (1772)
"Great vacation!"
United States
Sue
The price is €257
includes taxes & fees
11 Jan - 12 Jan
Margaritaville Beach Resort Fort Myers

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.4 out of 10, Exceptional, (1150)
"Is great place to stay."
United States
Anastassia
The price is €136
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Edison Beach House

Edison Beach House
3.5 star property
21.2 km from Sanctuary
9.4 out of 10, Exceptional, (1609)
"Location, staff, room with view…all were excellent. Will stay again!"
United States
Leah
Edison Beach House

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.6 out of 10, Excellent, (1018)
"Great stay"
United States
Erica
The price is €143
includes taxes & fees
15 Jan - 16 Jan
Hilton Garden Inn Ft Myers

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
18.8 km from Sanctuary
8.8 out of 10, Excellent, (271)
"Super clean! Super cute and easy for two. It is close to the road so we hear traffic, but the white noise helped with that. Communication was flawless! Would stay again. "
United States
Rhonda
The price is €177
includes taxes & fees
15 Jan - 16 Jan
Matlacha Tiny Village

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1220)
"Nice rooms, great having the bar onsite"
United States
Lee
The price is €145
includes taxes & fees
11 Jan - 12 Jan
Dolphin Key Resort

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1000)
"The staff were great, the hotel was excellent and we had a wonderful trip!"
United States
Dana
The price is €140
includes taxes & fees
11 Jan - 12 Jan
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Allure Suites

Allure Suites
3.0 star property
27.2 km from Sanctuary
7.6 out of 10, Good, (1000)
"Great service, location and facility "
United States
Franca
The price is €102
includes taxes & fees
11 Jan - 12 Jan
Allure Suites

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
22.3 km from Sanctuary
9.2 out of 10, Wonderful, (1015)
"Wonderful stay! "
United States
Brittany
DiamondHead Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.