Sanibel Hotel Guide. Hotels in Sanctuary, Sanibel, United States of America

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Our top choices for Sanctuary hotels

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (219 reviews)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is €120
includes taxes & fees
12 Jan - 13 Jan
Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is €272
includes taxes & fees
11 Jan - 12 Jan
The Westin Cape Coral Resort At Marina Village

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,003 reviews)
"Beautiful place "
United States
Blaine
The price is €82
includes taxes & fees
17 Jan - 18 Jan
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.4 out of 10, Exceptional, (1,151 reviews)
"Is great place to stay."
United States
Anastassia
The price is €136
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"The staff were great, the hotel was excellent and we had a wonderful trip!"
United States
Dana
The price is €148
includes taxes & fees
19 Jan - 20 Jan
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,220 reviews)
"Nice rooms, great having the bar onsite"
United States
Lee
The price is €145
includes taxes & fees
18 Jan - 19 Jan
Dolphin Key Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (149 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is €271
includes taxes & fees
22 Jan - 23 Jan
Off the Charts Inn & Out Island Resort

White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.0 out of 10, Very good, (49 reviews)
"Place was nice and private. "
United States
Dawn
The price is €115
includes taxes & fees
10 Jan - 11 Jan
White Orchid Apartments

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very good, (11 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is €106
includes taxes & fees
10 Jan - 11 Jan
Summerwind Studios

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,520 reviews)
"Great location. "
United States
Patricia
The price is €269
includes taxes & fees
11 Jan - 12 Jan
Sanibel Island Beach Resort

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.2 out of 10, Very good, (17 reviews)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is €116
includes taxes & fees
10 Jan - 11 Jan
TriLuxe Inn & Studios

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1,003 reviews)
"Great location "
United States
Lance
The price is €365
includes taxes & fees
10 Jan - 11 Jan
Marriott Sanibel Harbour Resort & Spa

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,002 reviews)
"Great place to stay."
United States
David
The price is €125
includes taxes & fees
20 Jan - 21 Jan
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay "
United States
Brandon
The price is €163
includes taxes & fees
11 Jan - 12 Jan
Doubletree by Hilton Fort Myers at Bell Tower Shops

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.6 out of 10, Excellent, (1,018 reviews)
"Great stay"
United States
Erica
The price is €143
includes taxes & fees
15 Jan - 16 Jan
Hilton Garden Inn Ft Myers

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location"
United States
Sandra
The price is €383
includes taxes & fees
1 Feb - 2 Feb
Sanibel Inn

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1,000 reviews)
"We absolutely love staying here. Everytime we visit florida we come to this hotel. They offer everything you need for a family of 6, makes vacationing alot easier for us parents!"
United States
Kassie
The price is €159
includes taxes & fees
22 Jan - 23 Jan
Residence Inn by Marriott Fort Myers Sanibel

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (799 reviews)
"Great price close to my amenities. "
Canada
Gerry
The price is €107
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Island Inn

Island Inn
3.5 star property
West End, 9.6 km from Sanctuary
9.4 out of 10, Exceptional, (1,124 reviews)
"Really nice, updated, and clean room with a screened waterfront balcony in a perfect place on the island (far enough away from the big resorts to be in a quieter area, but close enough to the center area of the island to be convenient). "
United States
Chris
The price is €276
includes taxes & fees
11 Jan - 12 Jan
Island Inn

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean and tidy hotel, friendly staff and the breakfast is excellent. 4th time we have stayed here in last 15 months"
United Kingdom
Adam
The price is €166
includes taxes & fees
11 Jan - 12 Jan
Homewood Suites by Hilton - Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.