Santa Cruz Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €900 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Flight + Hotel Deals in Santa Cruz

Price found within the past 48 hours. Click for updated prices.
Casa Decu

Casa Decu

La Condesa
€1,429
per person
9 Dec - 15 Dec
found 22 hours ago
Return direct flight included
Ankara (ESB) to Mexico City (MEX)
9.4/10 Exceptional! (1,007 reviews)
Hotel Luca

Hotel Luca

Roma Norte
€1,864
per person
9 Dec - 15 Dec
found 22 hours ago
Return direct flight included
Ankara (ESB) to Mexico City (MEX)
9.2/10 Wonderful! (436 reviews)
Gran Hotel Ciudad de Mexico Zocalo View

Gran Hotel Ciudad de Mexico Zocalo View

Historic Center
€1,865
per person
9 Dec - 15 Dec
found 22 hours ago
Return direct flight included
Ankara (ESB) to Mexico City (MEX)
9.6/10 Exceptional! (1,303 reviews)
I loved this Hotel The purpose of my trip was to visit the Basilica, I chose this hotel because it was at the zocalo , only 20 to 25 minutes driving distance. The surrounding areas are very walkable so many people just enjoying themselves and having a good time. The food in the hotel it was delicious., also we walk to a different restaurants around the corner and I have the same experience.

Reviewed on 25 Oct 2026

Alteza Polanco

Alteza Polanco

Polanco
€1,646
per person
9 Dec - 15 Dec
found 22 hours ago
Return direct flight included
Ankara (ESB) to Mexico City (MEX)
8.6/10 Excellent! (688 reviews)
The breakfast restaurant is excellent. The staff were very friendly and helpful. The accommodation was very nice, modern and clean.

Reviewed on 23 Oct 2026

Hotel Canada Central

Hotel Canada Central

Historic Center
€1,452
per person
9 Dec - 15 Dec
found 22 hours ago
Return direct flight included
Ankara (ESB) to Mexico City (MEX)
9.2/10 Wonderful! (1,300 reviews)
Great value, excellent location

Reviewed on 24 Oct 2026

Top hotels in Santa Cruz

InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

Campos Eliseos 218 Mexico City
€511
16 Nov - 17 Nov
includes taxes & fees
InterContinental Presidente Mexico City by IHG
Casa Olea

Casa Olea

C. de Francisco Díaz Covarrubias Mexico City CDMX
Fully refundableReserve now, pay when you stay
€58
24 Nov - 25 Nov
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
"It’s my second time booking this hotel. The staff is friendly and helpful. The beds are comfortable and you can actually sleep. Wish security and the staff made sure that quiet hours more closely observed. Other guests tend to not know how to handle themselves sometimes and they violate quiet hours. ..."

Reviewed on 24 Oct 2026

Casa Olea
Hyatt Regency Mexico City

Hyatt Regency Mexico City

Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
€366
23 Nov - 24 Nov
includes taxes & fees
Hyatt Regency Mexico City
See all 1,602 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa Cruz

Immerse in the Nature: Deep Connection through Forest Bathing

Immerse in the Nature: Deep Connection through Forest Bathing

€69
per adult
Immerse in the Nature: Deep Connection through Forest Bathing
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Offering excellent value package deals from €1,429 on Expedia, you'll be pleasantly surprised at how much a holiday to Santa Cruz costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa Cruz?
You can usually find reduced prices and better availability in January, February and June. Explore our cheap Santa Cruz holiday packages and you could score some great off-season discounts.
How many days is enough for Santa Cruz?
The ideal duration for your Santa Cruz holiday depends on what you'd like to see. Typically, a few days to a week will give you time to hit all the top attractions and discover some hidden treasures along the way.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is a breeze with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalise your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Santa Cruz holiday as a package?
Expedia holiday packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component individually. And you'll still enjoy the freedom to create a customised Santa Cruz holiday by choosing your preferred accommodation type, airline and car class.
When to book a holiday package to Santa Cruz?
If you're planning a spontaneous Santa Cruz trip, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can land incredible deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?
  1. Choose your dates: The things you want to do in Santa Cruz and your favourite season can help you decide when to go.
  2. Set a budget: Consider expenses such as flights, food and transportation when calculating how much to put aside for your trip to Santa Cruz. Then, pick a hotel that matches your budget, whether that's an economical stay or a swankier retreat.
  3. Decide your trip length: Consider how much time you want to spend exploring Santa Cruz. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing.
  4. Combine your accommodation and airfare: Once you've nailed down your travel dates and duration, book the ideal Santa Cruz holiday package for you.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.