Santa Cruz Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Hotel Finca Las Hortensias

Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very good, (188 reviews)
"Nice rooms and grounds."
United States
Raymond
Hotel Finca Las Hortensias

La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
8.0 out of 10, Very good, (40 reviews)
"na"
Mexico
Karina Ponce
La Morada Tepotzotlan Boutique & Spa

Villa Granada

Villa Granada
2.0 star property
Tecamac
9.0 out of 10, Wonderful, (57 reviews)
"One of the best Hotels for that area. "
United States
GUSTAVO
The price is €41
includes taxes & fees
9 Mar - 10 Mar
Villa Granada

Antigua Hotel Boutique

Antigua Hotel Boutique
3.5 star property
Ciudad López Mateos
9.4 out of 10, Exceptional, (116 reviews)
"Great location and service."
United States
Jorge Gabriel
Antigua Hotel Boutique

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
3.5 star property
Zumpango
9.4 out of 10, Exceptional, (1,080 reviews)
"Good, clean, close to airport "
United States
Darylle
The price is €135
includes taxes & fees
13 Mar - 14 Mar
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Verticca Hotel

Verticca Hotel
3.0 star property
Ojo de Agua
9.2 out of 10, Wonderful, (269 reviews)
"Everything was great we like the place."
United States
Gilberto
Verticca Hotel

KALI La Raza Mexico City

KALI La Raza Mexico City
2.5 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (275 reviews)
"This place was great. Super clean. Close to all attractions. "
United States
Luis Emanuel
KALI La Raza Mexico City

Hotel Único La Villa

Hotel Único La Villa
2.0 star property
Gustavo A. Madero
6.6 out of 10, (24 reviews)
"."
United States
Eduardo
The price is €53
includes taxes & fees
9 Mar - 10 Mar
Hotel Único La Villa

HOTEL CASA KAVIA

HOTEL CASA KAVIA
2.0 star property
Miguel Hidalgo
9.6 out of 10, Exceptional, (49 reviews)
"Beautiful place. Great location. Friendly staff. "
United States
Raul
The price is €136
includes taxes & fees
9 Mar - 10 Mar
HOTEL CASA KAVIA

Fiesta Inn Ecatepec

Fiesta Inn Ecatepec
3.5 star property
Ecatepec de Morelos
8.8 out of 10, Excellent, (903 reviews)
"Room was great service and clean and great staff"
United States
LUIS
The price is €103
includes taxes & fees
15 Mar - 16 Mar
Fiesta Inn Ecatepec

Hot Plaza del Rey | Love Hotel | Solo Adultos

Hot Plaza del Rey | Love Hotel | Solo Adultos
2.5 star property
Azcapotzalco
7.6 out of 10, Good, (82 reviews)
"everything was very good, thanks "
United States
Javier
Hot Plaza del Rey | Love Hotel | Solo Adultos

Hotel Brasilia

Hotel Brasilia
3.0 star property
Gustavo A. Madero
9.0 out of 10, Wonderful, (1,005 reviews)
"The room was very clean and spacious, and the staff was very friendly. I would stay there again."
United States
guillermo guerrero
The price is €77
includes taxes & fees
12 Mar - 13 Mar
Hotel Brasilia

City Express by Marriott Tepotzotlan

City Express by Marriott Tepotzotlan
3.5 star property
Tepotzotlán
8.6 out of 10, Excellent, (747 reviews)
"Just few yards before the Tepotzotlan toll booth. Great for overnight stay "
United States
VICTOR
The price is €57
includes taxes & fees
22 Mar - 23 Mar
City Express by Marriott Tepotzotlan

Kukun Homero Polanco

Kukun Homero Polanco
4.0 star property
Polanco
9.4 out of 10, Exceptional, (270 reviews)
"Amazing place near to everything with a lot of great amenities"
United States
Mauricio Meza
The price is €120
includes taxes & fees
9 Mar - 10 Mar
Kukun Homero Polanco

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG
3.0 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (1,099 reviews)
"Very quit and clean place to stay"
Canada
Mary Jane
The price is €70
includes taxes & fees
24 Mar - 25 Mar
Holiday Inn Express Mexico Basilica by IHG

Fairfield Inn & Suites Mexico City Vallejo

Fairfield Inn & Suites Mexico City Vallejo
3.0 star property
Azcapotzalco
9.2 out of 10, Wonderful, (1,004 reviews)
"The room was clean, employees very courteous."
United States
Miguel
The price is €98
includes taxes & fees
13 Mar - 14 Mar
Fairfield Inn & Suites Mexico City Vallejo

Hotel Vía la Villa

Hotel Vía la Villa
2.5 star property
Gustavo A. Madero
8.0 out of 10, Very good, (355 reviews)
"Yes"
United States
Naz George
Hotel Vía la Villa

One Cuautitlan

One Cuautitlan
3.0 star property
Cuautitlan Izcalli
8.8 out of 10, Excellent, (573 reviews)
"Exelente"
Mexico
Juan Tadeo
The price is €66
includes taxes & fees
16 Mar - 17 Mar
One Cuautitlan

Hot Elite | Love Hotel | Solo Adultos

Hot Elite | Love Hotel | Solo Adultos
3.0 star property
Miguel Hidalgo
8.0 out of 10, Very good, (14 reviews)
"Everything turned out great. We were attended by courteous staff, the room was in perfect shape and with a great view, all in all this was a fantastic stay. "
United States
alex
Hot Elite | Love Hotel | Solo Adultos

Real Inn Perinorte

Real Inn Perinorte
4.0 star property
Tlalnepantla de Baz
8.6 out of 10, Excellent, (1,011 reviews)
"Excelente "
Mexico
Ruben
The price is €71
includes taxes & fees
19 Mar - 20 Mar
Real Inn Perinorte
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

Where is the best place for a stay in Santa Cruz?
Located 18.9 mi (30.4 km) from the heart of Santa Cruz, Hyatt Regency Mexico City is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are InterContinental Presidente Mexico City by IHG and Downtown Treasure Place. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Polanco Stay: Outdoor Space & Explore Nearby: This holiday home rental outside of Santa Cruz offers a garden, a selection of games and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Those travelling to Santa Cruz will definitely enjoy the sights to see and things to do. In Santa Cruz, there are 2 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What are the top places to visit in Santa Cruz?
Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually April and May, with an average temperature of 18°C, while the coldest months are January and December, with an average of 14°C. The rainiest months in Santa Cruz are August, July, September and June, with each month seeing an average of 186 mm of rainfall.

Explore a world of travel with Expedia