
Santa Lucia Holidays
- Plan, book, travel with confidence
Better together
Save up to €185 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia

Ortigia
3 out of top 10 points of interest in this area
4.5/5(49 area reviews)
Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.
Top hotels in Santa Lucia

Grande Albergo Alfeo
Via Nino Bixio 5, Syracuse, SR
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (625 reviews)
Charming Sicilian Hotel near Ortiga & marina
"Charming Sicilian Hotel within walking distance to bustling Ortiga. Lots of restaurants and shops nearby. Friendly staff and delicious daily breakfast with made to order cafe. Bonus- complimentary granita provided to hotel guests daily in the lobby. A/C is a welcome respite to escape the hot summer ..."
Reviewed on 29 Jun 2025

Caportigia Boutique Hotel
Viale Montedoro 76, Syracuse, SR
Fully refundableReserve now, pay when you stay
The price is €215 per night from 21 Aug to 22 Aug
€215
21 Aug - 22 Aug
includes taxes & fees
9.2/10 Wonderful! (239 reviews)
"The hotel was truly lovely, clean and in a perfect location for all our jaunts; we were greeted warmly by all staff we encountered. The included Buffet Breakfast was varied and fresh. We did not try the in-house restaurant but the menu was very interesting snd upscale. I highly recommend the Caportigia ..."
Reviewed on 9 Aug 2025

Nostos rooms & Apartments
Corso Umberto I, 66, Syracuse, SR
Fully refundableReserve now, pay when you stay
The price is €102 per night from 9 Sept to 10 Sept
€102
9 Sept - 10 Sept
includes taxes & fees
9/10 Wonderful! (257 reviews)
"Very welcoming staff"
Reviewed on 14 May 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
Madonna delle Lacrime
You can study the exhibits at Madonna delle Lacrime, a museum with a story of its own, during your holiday in Syracuse. Wander the seaside in this culturally rich area.
Things to do

Tour of the island of Ortigia and exploration of sea caves with baths.
€25
per adult
100% of travellers recommend

Boat tour Ortigia, sea caves and Pillirina 2h
€40
per adult
100% of travellers recommend

Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
€40
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.